抗体

NFKBIB, CT (NFKBIB, IKBB, TRIP9, NF-kappa-B inhibitor beta, I-kappa-B-beta, Thyroid receptor-interacting protein 9) (APC)

038941-APC

200微升

711美元

多克隆

domestic rabbit

APC

NFKBIB, CT (NFKBIB, IKBB, TRIP9, NF-kappa-B inhibitor beta, I-kappa-B-beta, Thyroid receptor-interacting protein 9) (APC)

兔

多克隆抗体

APC

抗体

200微升

711美元

IgG

NFKB1 (MIM 164011) or NFKB2 (MIM 164012) is bound to REL (MIM 164910), RELA (MIM 164014), or RELB (MIM 604758) to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA, MIM 164008, or NFKBIB), which inactivate NF-kappa-B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, MIM 600664 or IKBKB, MIM 603258) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T; R is an A or G purine; and Y is a C or T pyrimidine). Applications: Suitable for use in Western Blot, Immunohistochemistry, FLISA Recommended Dilution: FLISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:10-50 Storage and Stability: Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.

Hu

NFKBIB, IKBB, TRIP9, NF-kappa-B inhibitor beta, I-kappa-B-beta, Thyroid receptor-interacting protein 9

NFKBIB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 325-355 amino acids from the C-terminal region of human NFKBIB.

人类

Purified by Protein A affinity chromatography.

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).

As reported

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC). Purity: Purified by Protein A affinity chromatography. Immunogen: NFKBIB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 325-355 amino acids from the C-terminal region of human NFKBIB. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

FL免疫组化免疫印迹

4°C不冻结

Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Potter, C., et al. Ann. Rheum. Dis. 69(7):1315-1320(2010) Segat, L., et al. Vaccine 28(10):2201-2206(2010) McGeachie, M., et al. Circulation 120(24):2448-2454(2009) Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)

https://usbio-images.r.worldssl.net/prodimages/25/038941-APC_1.jpg