抗体

PTPN22, CT (PTPN22, PTPN8, Tyrosine-protein phosphatase non-receptor type 22, Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP, Lymphoid phosphatase, PEST-domain phosphatase)

040664

200微升

569美元

多克隆

domestic rabbit

未共轭

PTPN22, CT (PTPN22, PTPN8, Tyrosine-protein phosphatase non-receptor type 22, Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP, Lymphoid phosphatase, PEST-domain phosphatase)

兔

多克隆抗体

抗体

200微升

569美元

IgG

This gene encodes of member of the non-receptor class 4 subfamily of the protein-tyrosine phosphatase family. The encoded protein is a lymphoid-specific intracellular phosphatase that associates with the molecular adapter protein CBL and may be involved in regulating CBL function in the T-cell receptor signaling pathway. Mutations in this gene may be associated with a range of autoimmune disorders including Type 1 Diabetes, rheumatoid arthritis, systemic lupus erythematosus and Graves' disease. Alternatively spliced transcript variants encoding distinct isoforms have been described. Applications: Suitable for use in Western Blot and ELISA. Other applications have not been tested. Recommended Dilution: Western Blot: 1:1000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Hu

PTPN22, PTPN8, Tyrosine-protein phosphatase non-receptor type 22, Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP, Lymphoid phosphatase, PEST-domain phosphatase

KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 663-691 in the C-terminal region of human PTPN22, UniProt Accession #Q9Y2R2.

识别人类PTPN22

Purified by Protein A affinity chromatography.

以溶解在PBS液体方式提供, pH值7.2, 0.09% 叠氮化钠

As reported

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. Purity: Purified by Protein A affinity chromatography. Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 663-691 in the C-terminal region of human PTPN22, UniProt Accession #Q9Y2R2. Specificity: Recognizes human PTPN22. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

E免疫印迹

-20°C

Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Andersen, M.K., et al. Diabetes Care 33(9):2062-2064(2010) Bianco, B., et al. Scand. J. Immunol. 72(3):256-259(2010) Pradhan, V., et al. J Postgrad Med 56(3):239-242(2010) Sfar, I., et al. Arch Inst Pasteur Tunis 86 (1-4), 51-62 (2009) :

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