产品简要
公司名称 :
US Biological
产品类型 :
抗体
产品名称 :
蛋白酪氨酸磷酸酶受体C, NT(蛋白酪氨酸磷酸酶受体C, CD45, 受体类型酪氨酸蛋白磷酸酶C, 白细胞共同抗原, T200, CD45)
目录 :
040667
规格 :
200微升
价格 :
569美元
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类
更多信息或购买 :
产品信息
目录号 :
040667
Product wo Prefix :
蛋白酪氨酸磷酸酶受体C, NT(蛋白酪氨酸磷酸酶受体C, CD45, 受体类型酪氨酸蛋白磷酸酶C, 白细胞共同抗原, T200, CD45)
宿主 :
产品类型 :
多克隆抗体
类别 :
抗体
尺寸1 :
200微升
Size1 List :
569美元
抗体亚型 :
IgG
Desc1 :
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus belongs to receptor type PTP. This gene is specifically expressed in hematopoietic cells. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Four alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq]. Applications: Suitable for use in Western Blot, Flow Cytometry and ELISA. Other applications have not been tested. Recommended Dilution: Western Blot: 1:1000 Flow Cytometry: 1:10-1:50 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Calc Crossreactivity :
Hu
又名 :
蛋白酪氨酸磷酸酶受体C, CD45, 受体类型酪氨酸蛋白磷酸酶C, 白细胞共同抗原, T200, CD45
免疫原 :
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 336-364 of human PTPRC.
特异性 :
识别人类蛋白酪氨酸磷酸酶受体C
纯度 :
Purified by Protein A and peptide affinity chromatography.
形式 :
以溶解在PBS液体方式提供, pH值7.2, 0.09% 叠氮化钠
浓度 :
As reported
Desc2 :
Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. Purity: Purified by Protein A and peptide affinity chromatography. Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 336-364 of human PTPRC. Specificity: Recognizes human PTPRC. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Calc Applications Abbrev :
E FC免疫印迹
储存温度 :
-20°C
参考文献 :
1. Heyd, F., et al. Mol. Cell 40(1):126-137(2010) 2. Wu, Z., et al. J. Immunol. 185(1):231-238(2010) 3. Cui, J., et al. Arthritis Rheum. 62(7):1849-1861(2010) 4. Booth, N.J., et al. J. Immunol. 184(8):4317-4326(2010) 5. Capitanescu, B., et al. Rom J Morphol Embryol 51(1):49-54(2010)
Picture 1 File Name :
https://usbio-images.r.worldssl.net/prodimages/12/040667_1.png
更多信息或购买 :
公司信息
US Biological
4 Technology Way
Salem, MA01970
tech@usbio.net
https://www.usbio.net
800-520-3011 781-639-5092
公司总部: 美国
United States Biological是生命科学领域的知名品牌,致力于用真实、有价值的个性化采购经验降低研究用成本。