抗体

SNAP23, CT (SNAP23, Synaptosomal-associated protein 23, Vesicle-membrane fusion protein SNAP-23)

042075

200微升

569美元

多克隆

domestic rabbit

未共轭

SNAP23, CT (SNAP23, Synaptosomal-associated protein 23, Vesicle-membrane fusion protein SNAP-23)

兔

多克隆抗体

抗体

200微升

569美元

IgG

Specificity of vesicular transport is regulated, in part, by the interaction of a vesicle-associated membrane protein termed synaptobrevin/VAMP with a target compartment membrane protein termed syntaxin. These proteins, together with SNAP25 (synaptosome-associated protein of 25 kDa), form a complex which serves as a binding site for the general membrane fusion machinery. Synaptobrevin/VAMP and syntaxin are believed to be involved in vesicular transport in most, if not all cells, while SNAP25 is present almost exclusively in the brain, suggesting that a ubiquitously expressed homolog of SNAP25 exists to facilitate transport vesicle/target membrane fusion in other tissues. The protein encoded by this gene is structurally and functionally similar to SNAP25 and binds tightly to multiple syntaxins and synaptobrevins/VAMPs. It is an essential component of the high affinity receptor for the general membrane fusion machinery and is an important regulator of transport vesicle docking and fusion. Two alternative transcript variants encoding different protein isoforms have been described for this gene. Applications: Suitable for use in Western Blot, Immunohistochemistry, ELISA Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:10-50 Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Hu

SNAP23, Synaptosomal-associated protein 23, Vesicle-membrane fusion protein SNAP-23

SNAP23 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 169-199 amino acids from the C-terminal region of human SNAP23.

人类

Purified by Protein A affinity chromatography.

以溶解在PBS液体方式提供, pH值7.2, 0.09% 叠氮化钠

As reported

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. Purity: Purified by Protein A affinity chromatography. Immunogen: SNAP23 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 169-199 amino acids from the C-terminal region of human SNAP23. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

E免疫组化免疫印迹

-20°C

Greaves, J., et al. J. Biol. Chem. 285(32):24629-24638(2010) Bostrom, P., et al. Diabetes 59(8):1870-1878(2010) Ban, H.J., et al. BMC Genet. 11, 26 (2010) : Kean, M.J., et al. J. Cell. Sci. 122 (PT 22), 4089-4098 (2009) : Gratacos, M., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 150B (6), 808-816 (2009) :

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