抗体

TIMP1, CT (TIMP1, CLGI, TIMP, Metalloproteinase inhibitor 1, Erythroid-potentiating activity, Fibroblast collagenase inhibitor, Tissue inhibitor of metalloproteinases 1)

042849

200微升

569美元

多克隆

domestic rabbit

未共轭

TIMP1, CT (TIMP1, CLGI, TIMP, Metalloproteinase inhibitor 1, Erythroid-potentiating activity, Fibroblast collagenase inhibitor, Tissue inhibitor of metalloproteinases 1)

兔

多克隆抗体

抗体

200微升

569美元

IgG

This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. Applications: Suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence, Flow Cytometry, ELISA Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:50-100 Immunohistochemistry: 1:50-100 Immunofluorescence: 1:10-50 Flow Cytometry: 1:10-50 Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Hu

TIMP1, CLGI, TIMP, Metalloproteinase inhibitor 1, Erythroid-potentiating activity, Fibroblast collagenase inhibitor, Tissue inhibitor of metalloproteinases 1

TIMP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 164-195 amino acids from the C-terminal region of human TIMP1.

人类

Purified by saturated ammonium sulfate precipitation followed by dialysis against PBS.

以溶解在PBS液体方式提供, pH值7.2, 0.09% 叠氮化钠

As reported

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. Purity: Purified by saturated ammonium sulfate precipitation followed by dialysis against PBS. Immunogen: TIMP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 164-195 amino acids from the C-terminal region of human TIMP1. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

E FC IF免疫组化免疫印迹

-20°C

Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) : Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Lin, C.C., et al. Clin J Am Soc Nephrol 5(10):1805-1814(2010) Yeh, Y.C., et al. BMC Microbiol. 10, 218 (2010) : Johnatty, S.E., et al. PLoS Genet. 6 (7), E1001016 (2010) :

https://usbio-images.r.worldssl.net/prodimages/28/042849_1.jpg

Confocal immunofluorescent analysis of TIMP1 Antibody (C-term) with A2058 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red).

https://usbio-images.r.worldssl.net/prodimages/28/042849_5.jpg

TIMP1 Antibody (C-term) flow cytometric analysis of A2058 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.