抗体

TLR6, CT(TLR6, Toll样受体6, CD286)(AP)

042880-AP

200微升

711美元

多克隆

domestic rabbit

AP

TLR6, CT(TLR6, Toll样受体6, CD286)(AP)

兔

多克隆抗体

AP

抗体

200微升

711美元

IgG

TLR6, a Type I membrane protein that belongs to the Toll-like rceptor family, participates in the innate immune response to Gram-positive bacteria and fungi. It acts via MyD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. The protein recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR2. It binds to TLR2 via their respective extracellular domains, and to MyD88 via their respective TIR domains. TLR6 is detected in monocytes, CD11c+ immature dendritic cells, plasmacytoid pre-dendritic cells and dermal microvessel endothelial cells. Applications: Suitable for use in Western Blot, Immunohistochemistry, ELISA Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:50-100 1:10-50 Storage and Stability: Store product at 4°C. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.

Hu

TLR6, Toll样受体6, CD286

TLR6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 401~431 amino acids from C-terminal region of human TLR6.

人类

Purified by Protein G affinity chromatography.

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP).

As reported

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP). Purity: Purified by Protein G affinity chromatography. Immunogen: TLR6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 401~431 amino acids from C-terminal region of human TLR6. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

E免疫组化免疫印迹

4°C不冻结

Bulut, Y., et al., J. Immunol. 167(2):987-994 (2001). Takeuchi, O., et al., Gene 231 (1-2), 59-65 (1999).

https://usbio-images.r.worldssl.net/prodimages/49/042880-AP_1.jpg

Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with TLR6 antibody (C-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.