抗体

泛肽, CT(UBC, 多聚泛肽C, 泛肽)(AP)

043544-AP

200微升

711美元

多克隆

domestic rabbit

AP

泛肽, CT(UBC, 多聚泛肽C, 泛肽)(AP)

兔

多克隆抗体

AP

抗体

200微升

711美元

IgG

This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin is required for ATP-dependent, nonlysosomal intracellular protein degradation of abnormal proteins and normal proteins with a rapid turnover. Ubiquitin is covalently bound to proteins to be degraded, and presumably labels these proteins for degradation. Ubiquitin also binds to histone H2A in actively transcribed regions but does not cause histone H2A degradation, suggesting that ubiquitin is also involved in regulation of gene expression. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. Aberrant form of this protein has been noticed in patients with Alzheimer's and Down syndrome. Applications: Suitable for use in Western Blot, Immunohistochemistry and ELISA. Other applications have not been tested. Recommended Dilutions: Immunohistochemistry: Formalin fixed and paraffin embedded tissues Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.

Hu

UBC, 多聚泛肽C, 泛肽

KLH-conjugated synthetic peptide mapping to a fragment of residues within aa36-66 of human Ubiquitin. Species Sequence Homology: yeast, bovine, C. elegans, Drosophila, monkey, mouse, porcine, rat, sheep, chicken equine, hamster, Xenopus and rabbit

识别人的泛素

Purified by Protein A/G affinity chromatography.

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP).

As Reported

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As Reported Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP). Purity: Purified by Protein A/G affinity chromatography. Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within aa36-66 of human Ubiquitin. Species Sequence Homology: yeast, bovine, C. elegans, Drosophila, monkey, mouse, porcine, rat, sheep, chicken equine, hamster, Xenopus and rabbit Specificity: Recognizes human Ubiquitin. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

E免疫组化免疫印迹

4°C不冻结

1. Chan, Y.L., et al., Biochem. Biophys. Res. Commun. 215(2):682-690 (1995). 2. Cook, W.J., et al., J. Mol. Biol. 236(2):601-609 (1994). 3. Hubbard, M.J., et al., Biochim. Biophys. Acta 1200(2):191-196 (1994). 4. Wajih, N., et al., Protein Seq. Data Anal. 5(1):31-32 (1992). 5. Cook, W.J., et al., J. Biol. Chem. 267(23):16467-16471 (1992).

https://usbio-images.r.worldssl.net/prodimages/44/043544-AP_1.jpg