抗体

VASP, CT (VASP, Vasodilator-stimulated phosphoprotein)

043720

200微升

569美元

多克隆

domestic rabbit

未共轭

VASP, CT (VASP, Vasodilator-stimulated phosphoprotein)

兔

多克隆抗体

抗体

200微升

569美元

IgG

Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG. Applications: Suitable for use in Western Blot, Immunohistochemistry and ELISA. Other applications have not been tested. Recommended Dilution: Western Blot: 1:2000 Immunohistochemistry (FFPE): 1:10-1:50 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Hu

VASP, Vasodilator-stimulated phosphoprotein

KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 267-296 in the C-terminal region of human VASP, UniProt Accession #P50552.

识别人类VASP

Purified by Protein A and peptide affinity chromatography.

以溶解在PBS液体方式提供, pH值7.2, 0.09% 叠氮化钠

As reported

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. Purity: Purified by Protein A and peptide affinity chromatography. Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 267-296 in the C-terminal region of human VASP, UniProt Accession #P50552. Specificity: Recognizes human VASP. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

E免疫组化免疫印迹

-20°C

1. Barragan, P., et al. Thromb. Haemost. 104(2):410-411(2010) 2. Dittrich, M., et al. Arterioscler. Thromb. Vasc. Biol. 30(4):843-850(2010) 3. Gan, L., et al. Mol. Immunol. 47(6):1278-1282(2010) 4. Osmancik, P., et al. Catheter Cardiovasc Interv 75(2):158-166(2010) 5. Siller-Matula, J.M., et al. J. Thromb. Haemost. 8(2):351-359(2010)

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