抗体

CD34 (Hematopoietic Progenitor Cell Antigen, HPCA1, Mucosialin)

138511

20微克

353美元

单克隆

小鼠

未共轭

ICO-115

CD34 (Hematopoietic Progenitor Cell Antigen, HPCA1, Mucosialin)

小鼠

单克隆抗体

抗体

20微克

353美元

ICO-115

IgG1, k

This antibody recognizes a single chain, transmembrane, heavily glycosylated protein of 90-120kD, which is identified as CD34. Its expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, it is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. CD34 expression is also found in vascular endothelium. Additionally, it appears that proliferating endothelial cells overexpress this molecule than the non-proliferating endothelial cells. Anti-CD34 labels >85% of angiosarcoma and Kaposi's sarcoma, but shows low specificity. Applications: Suitable for use in Flow Cytometry, Western Blot and Immunofluorescence. Other applications not tested. Recommended Dilution: Flow Cytometry: 0.5-1ug/10e6 cells Western Blot: 0.5-1ug/ml Immunofluorescence: 0.5-1ug/ml Optimal dilutions to be determined by the researcher. Positive Control: KG-1 cells, tonsil, or angiosarcoma Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Hu Rt

Blast cells of a chronic myeloid leukemia patient

Recognizes human CD34. Species Crossreactivity: rat.

Purified by Protein A/G affinity chromatography.

Supplied as a liquid in PBS, 0.05% BSA, 0.05% sodium azide. Also available without BSA and azide, see 138511-AF.

~0.2毫克/毫升

Product Type: Mab Isotype: IgG1,k Clone No: ICO-115 Host: mouse Source: human Concentration: ~0.2mg/ml Form: Supplied as a liquid in PBS, 0.05% BSA, 0.05% sodium azide. Also available without BSA and azide, see 138511-AF. Purity: Purified by Protein A/G affinity chromatography. Immunogen: Blast cells of a chronic myeloid leukemia patient Specificity: Recognizes human CD34. Species Crossreactivity: rat. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

FC IF免疫印迹

-20°C

1. Felshow DM et al. Blood 97:3768-3775 (2001). 2. Sato T et al. Blood 94:2548-2554 (1999).

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