产品简要
公司名称 :
US Biological
产品类型 :
抗体
产品名称 :
ARP2 (Actin Like Protein 2, Actin-related Protein 2, ACTR2)
目录 :
A3574-91
规格 :
20微升
价格 :
342美元
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类
更多信息或购买 :
产品信息
目录号 :
A3574-91
Product wo Prefix :
ARP2 (Actin Like Protein 2, Actin-related Protein 2, ACTR2)
宿主 :
产品类型 :
多克隆抗体
类别 :
抗体
尺寸1 :
20微升
Size1 List :
342美元
抗体亚型 :
IgG
Desc1 :
Actin nucleation, the formation of new actin filaments from existing filaments, affects actin filament structure during cell motility, division and intracellular trafficking. An important actin nucleation protein complex is the highly conserved ARP2/3 complex, consisting of ARP2, ARP3 and ARPC1-5. The ARP2/3 complex promotes branching of an existing actin filament and formation of a daughter filament following activation by nucleation-promoting factors, such as WASP/WAVE or cortactin (1). The formation of podosomes, small cellular projections that degrade the extracellular matrix, is enhanced by ARP2/3 complex action. ARP2/3 competes with caldesmon, an actin binding protein shown to negatively affect podosome formation (2). The ARP2/3 complex (along with N-WASP) regulates nuclear actin filament nucleation and controls actin polymerization during transcription (3). Applications: Suitable for use in Western Blot. Other applications have not been tested. Recommended Dilutions: Western Blot: 1:1000, incubate membrane with diluted antibody in 5% BSA, 1X TBS, 0.1% Tween-20 at 4°C with gentle shaking, overnight. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Calc Crossreactivity :
Dr Hm Hu Mk Mo Rt
免疫原 :
合成多肽对应于序列人的ARP2
特异性 :
Recognizes endogenous levels of total human ARP2 protein. Species crossreactivity: mouse, rat, monkey, hamster and D. melanogaster.
纯度 :
血清
形式 :
Supplied as a liquid in 10mM sodium HEPES, pH 7.5, 150mM sodium chloride, 0.1mg/ml BSA, 50% glycerol.
浓度 :
未确定
Desc2 :
Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: Not determined Form: Supplied as a liquid in 10mM sodium HEPES, pH 7.5, 150mM sodium chloride, 0.1mg/ml BSA, 50% glycerol. Purity: Serum Immunogen: Synthetic peptide corresponding to the sequence of human ARP2. Specificity: Recognizes endogenous levels of total human ARP2 protein. Species crossreactivity: mouse, rat, monkey, hamster and D. melanogaster. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Calc Applications Abbrev :
免疫印迹
储存温度 :
-20°C
参考文献 :
1. Goley, E.D. and Welch, M.D. (2006) Nat. Rev. Mol. Cell Biol. 7, 713-726. 2. Morita, T. et al. (2007) J. Biol. Chem. 282, 8454-8463. 3. Yoo, Y. et al. (2007) J. Biol. Chem. 282, 7616-7623.
Picture 1 File Name :
https://usbio-images.r.worldssl.net/prodimages/17/A3574-91_1.jpg
更多信息或购买 :
公司信息
US Biological
4 Technology Way
Salem, MA01970
tech@usbio.net
https://www.usbio.net
800-520-3011 781-639-5092
公司总部: 美国
United States Biological是生命科学领域的知名品牌,致力于用真实、有价值的个性化采购经验降低研究用成本。