抗体

Hsp27(HSPB1, 热休克蛋白乙1, HspB1, 加热休克27kD蛋白, HSP 27)

H1830-59

100微克

472美元

多克隆

domestic rabbit

未共轭

Hsp27(HSPB1, 热休克蛋白乙1, HspB1, 加热休克27kD蛋白, HSP 27)

兔

多克隆抗体

抗体

100微克

472美元

IgG

Hsp27 exhibits a chaperone-like activity by serving as a site where unfolding proteins may bind until ATP and Hsp70-dependent refolding can occur. Hsp27 is believed to protect cells by enhancing cellular glutathione levels and elevated glutathione levels have been measured in cells overexpressing Hsp27. Data from studies using wild-type Hsp27 and mutant forms in which the serine phosphorylation sites were mutated to alanines, glycines or aspartates, have shown that cellular glutathione levels depend on the oligomerization of Hsp27. Recent findings indicate that Hsp27 is also a negative regulator of cytochrome c-dependent activation of procaspase-3. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 0.5-4ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Rt

合成多肽对应于aa193来自大鼠Hsp2

Recognizes rat Hsp27 at ~27kD.

Purified by affinity chromatography.

以溶解在PBS液体方式提供, pH值7.2, 0.5% BSA, 0.01% 硫柳汞, 30% 甘油

~0.5毫克/毫升

Product Type: Pab Isotype: IgG Host: rabbit Source: rat Concentration: ~0.5mg/ml Form: Supplied as a liquid in PBS, pH 7.2, 0.5% BSA, 0.01% thimerosal, 30% glycerol. Purity: Purified by affinity chromatography. Immunogen: Synthetic peptide corresponding to aa193 from rat Hsp2. Specificity: Recognizes rat Hsp27 at ~27kD. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

免疫印迹

-20°C

https://usbio-images.r.worldssl.net/prodimages/29/H1830-59_1.jpg