抗体

NDRG1 (Protein NDRG1, Differentiation-related Gene 1 Protein, DRG-1, N-myc Downstream-regulated Gene 1 Protein, Nickel-specific Induction Protein Cap43, Reducing Agents and Tunicamycin-responsive Protein, RTP, Rit42, CAP43, DRG1)

N2915-52E

100微克

521美元

多克隆

domestic goat

未共轭

NDRG1 (Protein NDRG1, Differentiation-related Gene 1 Protein, DRG-1, N-myc Downstream-regulated Gene 1 Protein, Nickel-specific Induction Protein Cap43, Reducing Agents and Tunicamycin-responsive Protein, RTP, Rit42, CAP43, DRG1)

www.usbio.net/antibodies/N2915-52E/NDRG1-Protein-NDRG1-Differentiationrelated-Gene-1-Protein-DRG1-Nmyc-Downstreamregulated-Gene-1-Protein-Nickelspecific-Induction-Protein-Cap43-Reducing-Agents-and-Tunicamycinresponsive-Protein-RTP-Rit42-CAP43-DRG1

山羊

多克隆抗体

抗体

100微克

521美元

IgG

NDRG1 is a member of the emerging NDRG family involved in stress responses, hormone responses, cell growth, and differentiation. The NDRG1 gene is mapped to human chromosome 8q24.2 and encodes a cytosolic protein containing three unique tandem repeats of 10 hydrophilic aa near the C-terminus. Expression of NDRG1 is markedly upregulated in various cells under such conditions as cell differentiation, hypoxia and exposure to heavy metals. However, its expression is repressed by the Myc family transcription factors and after cellular transformation. Mutations in the NDRG1 gene are linked to the hereditary motor and sensory neuropathy. The protein is ubiquitously expressed in human and rat heart, brain, kidney, placenta, lung, liver, skeletal muscle, and pancreas. Applications:. Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution:. ELISA: 1:32,000. Western Blot: 0.1-0.3ug/ml, observed in lysates of human brain, kidney and testis on ~48kD bands. Immunohistochemistry (Paraffin): 2-5ug/ml. Optimal dilutions to be determined by the researcher. Storage and Stability:. May be stored at 4 C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Ca Hu Mo Rt

Synthetic peptide corresponding to GNSAGPKSMEVSC, from human NDRG1, at C-terminal (NP_006087.2, NP_001128714.1).

Recognizes human NDRG1. Species sequence homology: Canine, mouse and rat.

经免疫亲和层析纯化

Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.

~0.5毫克/毫升

Product Type: Pab. Host: goat. Source: human. Concentration: ~0.5mg/ml. Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA. Purity: Purified by immunoaffinity chromatography. Immunogen: Synthetic peptide corresponding to GNSAGPKSMEVSC, from human NDRG1, at C-terminal (NP_006087.2, NP_001128714.1). Specificity: Recognizes human NDRG1. Species sequence homology: Canine, mouse and rat. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

E免疫组化免疫印迹

-20 C

1. Zhou D, Salnikow K, Costa M. Cap43, a novel gene specifically induced by Ni2+ compounds. Cancer Res. 1998 May 15;58(10):2182-9.

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