产品简要
公司名称 :
US Biological
产品类型 :
抗体
产品名称 :
NOD2 (CARD15, Nucleotide-binding Oligomerization Domain-containing Protein 2, Caspase Recruitment Domain-containing Protein 15, Inflammatory Bowel Disease Protein 1, IBD1)
目录 :
N3006-14N
规格 :
100微克
价格 :
532美元
克隆性 :
多克隆
宿主 :
domestic goat
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠
更多信息或购买 :
产品信息
目录号 :
N3006-14N
Product wo Prefix :
NOD2 (CARD15, Nucleotide-binding Oligomerization Domain-containing Protein 2, Caspase Recruitment Domain-containing Protein 15, Inflammatory Bowel Disease Protein 1, IBD1)
宿主 :
山羊
产品类型 :
多克隆抗体
类别 :
抗体
尺寸1 :
100微克
Size1 List :
532美元
抗体亚型 :
IgG
Desc1 :
NOD2 is an intracellular protein of 100kD, which belongs to the NOD (nucleotide binding oligomerisation domain) family. The NOD family comprises at present more than 20 different mammalian NOD-LRR (leucine-rich repeat) proteins, which are involved in the regulation of apoptosis and the immune response. NOD2 has been shown to be constitutively or inducibly expressed in monocytes, macrophages, T and B cells, dendritic cells, as well as intestinal epithelial cells. A specific motif of peptidoglycan (PGN), muramyl dipeptide (MDP), has been identified as the sole ligand of NOD2. NOD2 and Toll-like receptors (TLR) are emerging as key mediators of innate host defence in the intestinal mucosa, crucially involved in maintaining mucosal and commensal homeostasis. Mutations in the gene encoding NOD2 are a major susceptibility factor underlying a significant subgroup of patients with Crohn's disease. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:64,000 Western Blot: 0.1-0.3ug/ml, observed in lysates of human peripheral blood mononucleocytes on ~100kD bands Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Calc Crossreactivity :
Hu Mo Rt
免疫原 :
Synthetic peptide corresponding to KFRFTDRERHCSPTD, from human CARD15, at the internal region of the protein (NP_071445.1).
特异性 :
Recognizes human CARD15. Species sequence homology: Mouse and rat.
纯度 :
经免疫亲和层析纯化
形式 :
Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
浓度 :
~0.5毫克/毫升
Desc2 :
Product Type: Pab Host: goat Source: human Concentration: ~0.5mg/ml Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA. Purity: Purified by immunoaffinity chromatography. Immunogen: Synthetic peptide corresponding to KFRFTDRERHCSPTD, from human CARD15, at the internal region of the protein (NP_071445.1). Specificity: Recognizes human CARD15. Species sequence homology: Mouse and rat. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Calc Applications Abbrev :
E免疫印迹
储存温度 :
-20°C
Picture 1 File Name :
https://usbio-images.r.worldssl.net/prodimages/17/N3006-14N_1.jpg
更多信息或购买 :
公司信息
US Biological
4 Technology Way
Salem, MA01970
tech@usbio.net
https://www.usbio.net
800-520-3011 781-639-5092
公司总部: 美国
United States Biological是生命科学领域的知名品牌,致力于用真实、有价值的个性化采购经验降低研究用成本。