抗体

PAK1(丝氨酸/苏氨酸蛋白激酶PAK 1, 甲PAK, p21激活的激酶1, PAK-1, p65-PAK)

P2488-05F

100微克

493美元

多克隆

domestic rabbit

未共轭

PAK1(丝氨酸/苏氨酸蛋白激酶PAK 1, 甲PAK, p21激活的激酶1, PAK-1, p65-PAK)

兔

多克隆抗体

抗体

100微克

493美元

IgG

Human p21-GTPase-activated protein kinase 1 (PAK1) is a functional homolog of STE20 of Saccharomyces cerevisiae. PAK1 is a downstream effector of the Rho-family small GTPases Rac and Cdc42. A serine/threonine kinase, PAK1 induces the formation of filopodia and lamellipodia in Swiss 3T3 cells. PAK1 inhibits myosin light chain kinase, and appears to play a role in the regulation of apoptosis by phosphorylating the death agonist Bad. Membrane targeting of PAK1 induces neurite outgrowth. PAK1 may also regulate NFkB activation. Applications: Suitable for use in Western Blot and Immunoprecipitation. Other applications not tested. Recommended Dilution: Western Blot: 0.5-4ug/ml Immunoprecipitation: 10-20ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Hu

Recombinant protein corresponding to human PAK1.

识别人类PAK1

Purified by Protein A affinity chromatography.

以溶解在PBS液体方式提供, pH值7.2, 1% BSA, 0.02% 硫柳汞, 50% 甘油

~0.1毫克/毫升

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: ~0.1mg/ml Form: Supplied as a liquid in PBS, pH 7.2, 1% BSA, 0.02% thimerosal, 50% glycerol. Purity: Purified by Protein A affinity chromatography. Immunogen: Recombinant protein corresponding to human PAK1. Specificity: Recognizes human PAK1. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

免疫沉淀免疫印迹

-20°C

https://usbio-images.r.worldssl.net/prodimages/0/P2488-05F_1.jpg