抗体

Tau 13 (Microtubule-associated Protein tau, Neurofibrillary Tangle Protein, Paired Helical Filament-tau, PHF-tau, MAPTL, MTBT1, TAU, MAPT)

T1030-10G

100微升

595美元

单克隆

小鼠

未共轭

13A272

Tau 13 (Microtubule-associated Protein tau, Neurofibrillary Tangle Protein, Paired Helical Filament-tau, PHF-tau, MAPTL, MTBT1, TAU, MAPT)

小鼠

单克隆抗体

抗体

100微升

595美元

13A272

IgG1

Tau, a microtubule-binding protein which serves to stabilize microtubules in growing axons, is found to be hyperphosphorylated in paired helical filaments (PHF), the major fibrous component of neurofibrillary lesions associated with Alzheimer's disease. Hyperphosphorylation of Tau is thought to be the critical event leading to the assembly of PHF. Six Tau protein isoforms have been identified, all of which are phosphorylated by GSK3. This presents the possibility that miscues in GSK3 signaling contribute to the onset of Alzheimer's disease. Applications: Suitable for use in Western Blot, Immunoprecipitation and Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: 1:1000 Immunoprecipitation: 1:500 Immunohistochemistry: 1:100 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Hu

Synthetic peptide corresponding to the longest isoform of human Tau at N-terminus.

Recognizes human Tau-13 at ~45-60kD.

腹水

以溶解在PBS液体方式提供, 1% BSA, 0.02% 硫柳汞, 50% 甘油

未确定

Product Type: Mab Isotype: IgG1 Clone No: 13A272 Host: mouse Source: human Concentration: Not determined Form: Supplied as a liquid in PBS, 1% BSA, 0.02% thimerosal, 50% glycerol. Purity: Ascites Immunogen: Synthetic peptide corresponding to the longest isoform of human Tau at N-terminus. Specificity: Recognizes human Tau-13 at ~45-60kD. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

免疫组化免疫沉淀免疫印迹

-20°C