抗体

乙酰化微管蛋白(Lys40)小鼠单克隆

FNab00082

100微克

275USD

单克隆

小鼠

未共轭

免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学

乙酰化微管蛋白(Lys40)小鼠单克隆

抗体

小鼠

单克隆

未共轭

IgG1

100微克

275USD

Tubulin, composed of heterodimers of alpha and beta tubulin, is the mainly component of microtubules which play important roles in cell motility, mitosis, and intracellular vesicle transport. Both alpha and beta tubulin undergo several posttranslational modifications such as polyglutamylation and acetylation/deacetylation. Tubulin acetylation occurs on lysine-40 at the N-terminal of alpha tubulin and is conserved across species. The histone deacetylase HDAC6 and SIRT2 has been identified as tubulin deacetylases. Reversible acetylation of alpha tubulin may be implicated in regulating microtubule stability, cell motility, and axon regeneration. The level of acetylated tubulin has been linked to epithelial malignancies and sensitivity to chemotherapy. In addition, acetylated tubulin has been widely used as a marker for primary cilia. This antibody is specific to the acetylated tubulin; it does not recognize non-acetylated tubulin.

乙酰化α微管蛋白抗体, 乙酰化微管蛋白抗体, 乙酰化a抗体, 乙酰a抗体, α微管蛋白抗体, α微管蛋白3抗体, 微管蛋白抗体, TUBA1A抗体, 乙酰化微管蛋白(Lys40)抗体

Acetylated tubulin (Lys40) antibody: Mouse Monoclonal antibody to Acetylated tubulin (Lys40)

微管蛋白, 甲1a

人类, 小鼠, 大鼠, 狗

≥95% as determined by SDS-PAGE

酶联免疫吸附测定, 免疫印迹, 免疫组化, IF

PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)