产品简要
公司名称 :
武汉菲恩生物科技
产品类型 :
抗体
产品名称 :
HER2/v-erb-b2成红细胞白血病病毒致瘤基因2兔多克隆
目录 :
FNab03833
规格 :
100微克
价格 :
275USD
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
man
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫沉淀, 流式细胞仪
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产品信息
目录代码 :
FNab03833
产品名称 :
HER2/v-erb-b2成红细胞白血病病毒致瘤基因2兔多克隆
产品类型 :
抗体
宿主物种 :
兔
克隆性 :
多克隆
共轭 :
未共轭
抗体亚型 :
IgG
规格 :
100微克
标价 :
275USD
背景 :
HER2, also known as ErbB2 and Neu, is a 185-kDa transmembrane glycoprotein that is a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. It has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase- mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Amplification and/or overexpression of HER2 have been reported in numerous cancers, including breast and ovarian tumors. HER2 is a therapeutic target for the treatment of breast cancer and other carcinomas. This antibody raised against a synthesized peptide corresponding to 1237-1255aa of human HER2 recognizes the 185-kDa full-length glycosylated form and other lower molecular-mass forms of HER2, including the truncated form.
别名 :
HER2/v-erb-b2成红细胞白血病病毒致瘤基因2抗体
产品描述 :
HER2/ErbB2 antibody: Rabbit Polyclonal antibody to HER2/ErbB2
免疫原 :
v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)
特异性 :
人类
纯度 :
≥95% as determined by SDS-PAGE
应用摘要 :
酶联免疫吸附测定, 免疫印迹, 免疫组化, FC, 免疫沉淀
储存 :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
更多信息或购买 :
公司信息
武汉菲恩生物科技