抗体

NF-E2相关因子2, NFE2L2兔多克隆

FNab05855

100微克

275USD

多克隆

domestic rabbit

未共轭

免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫沉淀, 流式细胞仪

NF-E2相关因子2, NFE2L2兔多克隆

抗体

兔

多克隆

未共轭

IgG

100微克

275USD

NRF2, also named as NFE2L2, belongs to the bZIP family and CNC subfamily. It is a transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. NRF2 is important for the coordinated up-regulation of genes in response to oxidative stress. It may be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region.Nrf2 is a key player in the regulation of genes encoding for many antioxidative response enzymes.The expression of NRF2 may be induced under oxidative stress (PMID:14567983).In lung cancer, Nrf2 activation in malignant cells has been associated with tumor progression and chemotherapy resistance(PMID:20534738). Identifying patients with abnormal NRF2 expression may be important for selection for chemotherapy in NSCLC.

NF-E2相关因子2, NFE2L2抗体

NRF2, NFE2L2 antibody: Rabbit Polyclonal antibody to NRF2, NFE2L2

nuclear factor (erythroid-derived 2)-like 2

Human, Mouse , Rat，zebrafish

≥95% as determined by SDS-PAGE

酶联免疫吸附测定, 免疫沉淀, 免疫印迹, 免疫组化, FC

PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)