产品简要
公司名称 :
ichorbio
产品类型 :
抗体
产品名称 :
Anti-CD11a In Vivo Antibody - Low Endotoxin (38) [ICH1006] ichorbio
目录 :
ICH1006
规格 :
1毫克
价格 :
80 GBP
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
38
反应物种 :
人类
应用 :
免疫印迹, 流式细胞仪
更多信息或购买 :
产品信息
产品类型 :
低内毒素
ichorbio Cat Number :
ICH1006
Page Title :
Anti-CD11a In Vivo Antibody - Low Endotoxin (38) [ICH1006] ichorbio
Page Heading :
Anti-CD11a In Vivo Antibody - Low Endotoxin (38) [ICH1006]
Page Heading :
Bulk anti-CD11a In Vivo Antibody - Low Endotoxin (38)
Product Benefits :
ichorbio's anti-CD11a In Vivo Antibody - Low Endotoxin (38) is manufactured in a cGMP compliant, ISO Quality Standard 9001:2015 facility. ichorbio's low endotoxin antibodies have half the endotoxin of comparable antibodies from our competitors at less than 1.0 EU/mg. If ichorbio's low endotoxin antibodies are not low enough we also offer ultra low endotoxin antibodies which have even less endotoxin ( here for more information. ichorbio: the best antibodies for in vivo research.
靶标 :
CD11a
克隆 :
38
尺寸1 :
1毫克
Academic Price1 :
80 GBP
尺寸2 :
5mg
Academic Price2 :
240
Size3 :
25mg
Academic Price3 :
640
Size4 :
50mg
Academic Price4 :
1040
Size5 :
100mg
Academic Price5 :
1600
抗体亚型 :
小鼠IgG2a
其他名称 :
LFA-1甲, LFA-1A, 整合素甲L, ITGAL
UniProt数据库 :
P20701
宿主 :
小鼠
物种活性 :
人类
特异性 :
Anti-CD11a In Vivo Antibody - Low Endotoxin (38) recognizes Human CD11a. Anti-Human CD11a (Anti-LFA-1a) recognizes the (Mr 175 kDa) a chain of the leukocyte function associated antigen-1 (LFA-1). The leukocyte integrin LFA-1 is a member of a family of heterodimeric receptors that mediate divalent cation-dependent cellular adhesion reactions. LFA-1A binds to domain 1 of an intercellular adhesion molecule (ICAM) on target tissues.
纯化方法 :
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Antigen Distribution :
The CD11a antigen is present on most leukocytes and plays a vital role in cellular immune responses which require adhesion. Lymphocyte activation via the T-cell antigen receptor (TCR) up-regulates LFA-1 function. The absence of LFA-1A or B may induce the disease state known as leukocyte adhesion deficiency (LAD). Tumor cells which do not express LFA-1 may have avoided cellular immune-responses such as those carried out by natural killer cells (NK).
背景 :
Anti-CD11a may be used to study a variety of biological phenomena related to the function of cell adhesion molecules. This antibody may be used to study transplantation rejections and to assist in characterizing lymphomas and leukemias.
免疫原 :
未知
浓度 :
1.0-5.0毫克/毫升
配方 :
0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added. BSA and Azide free.
纯度 :
>95% by SDS-PAGE and HPLC
内毒素 :
≤ 1.0 EU/mg as determined by the LAL method
Aggregation :
Aggregation level ≤ 5%
储存 :
anti-CD11a In Vivo Antibody - Low Endotoxin (38) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
应用 :
流式细胞仪, 免疫印迹
应用注释 :
Each investigator should determine their own optimal working dilution for specific applications.
Isotype Control :
Mouse IgG2a In Vivo Isotype Control - Low Endotoxin [C1.18.4] (ICH2245)
Antibodies against the same target :
Anti-CD11a In Vivo Antibody - Low Endotoxin [FD441.8] (ICH1047) , Anti-CD11a In Vivo Antibody - Low Endotoxin [I21/7] (ICH1048)
Use :
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
价格说明 :
Contact for industrial pricing
更多信息或购买 :
公司信息
ichorbio
Grove Business Park
Downsview Road
Wantage OX12 9FF
hello@ichor.bio
https://www.ichor.bio
公司总部: 英国