产品简要
公司名称 :
ichorbio
产品类型 :
抗体
产品名称 :
Anti-CD20 In Vivo Antibody - Low Endotoxin (2H7) [ICH1012] ichorbio
目录 :
ICH1012
规格 :
1毫克
价格 :
80 GBP
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
2H7
反应物种 :
人类
应用 :
免疫印迹
更多信息或购买 :
ichorbio 产品网页
产品信息
产品类型 :
低内毒素
ichorbio Cat Number :
ICH1012
Page Title :
Anti-CD20 In Vivo Antibody - Low Endotoxin (2H7) [ICH1012] ichorbio
Page Heading :
Anti-CD20 In Vivo Antibody - Low Endotoxin (2H7) [ICH1012]
Page Heading :
Bulk anti-CD20 In Vivo Antibody - Low Endotoxin (2H7)
Product Benefits :
ichorbio's anti-CD20 In Vivo Antibody - Low Endotoxin (2H7) is manufactured in a cGMP compliant, ISO Quality Standard 9001:2015 facility. ichorbio's low endotoxin antibodies have half the endotoxin of comparable antibodies from our competitors at less than 1.0 EU/mg. If ichorbio's low endotoxin antibodies are not low enough we also offer ultra low endotoxin antibodies which have even less endotoxin ( here for more information. ichorbio: the best antibodies for in vivo research.
靶标 :
CD20
克隆 :
2H7
尺寸1 :
1毫克
Academic Price1 :
80 GBP
尺寸2 :
5mg
Academic Price2 :
240
Size3 :
25mg
Academic Price3 :
640
Size4 :
50mg
Academic Price4 :
1040
Size5 :
100mg
Academic Price5 :
1600
抗体亚型 :
小鼠IgG2b
其他名称 :
B-lymphocyte surface antigen B1, Bp35, Leukocyte surface antigen Leu-16, Membrane-spanning 4-domains subfamily A member 1, MS4A1
UniProt数据库 :
P11836
宿主 :
小鼠
物种活性 :
人类
特异性 :
Anti-CD20 In Vivo Antibody - Low Endotoxin (2H7) recognizes an epitope on Human CD20
纯化方法 :
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
背景 :
The CD20 antigen, also called MS4A1, B1 and Bp35, is a non-glycosylated, transmembrane spanning, phosphoprotein. The CD20 protein is present on human pre B lymphocytes and on B lymphocytes at all stages of maturation, except on plasma cells, and is synchronous with the expression of surface IgM. It is also expressed in some follicular dendritic cells and at low levels on a T cell subset. CD20 has been shown to be heavily phosphorylated in activated B cells and malignant B cells. Homo-oligomeric complexes of CD20 are thought to form Ca2+ conductive ion channels in the plasma membrane of B cells. The CD20 molecule is involved in B cell activation and is associated with various Src family kinases (Lyn, Lck, Fyn), and exists in a complex with MHC class I and II, CD53, CD81, and CD82. Extensive CD20 cross-linking may also influence cell death by apoptosis. Therapy with antibodies against CD20 is a widely used regimen in the treatment of all B cell lymphomas and leukemias.
浓度 :
1.0-5.0毫克/毫升
配方 :
0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added. BSA and Azide free.
纯度 :
>95% by SDS-PAGE and HPLC
内毒素 :
≤ 1.0 EU/mg as determined by the LAL method
Aggregation :
Aggregation level ≤ 5%
储存 :
anti-CD20 In Vivo Antibody - Low Endotoxin (2H7) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
应用 :
Western Blot, Functional Assays
应用注释 :
Each investigator should determine their own optimal working dilution for specific applications.
Isotype Control :
Mouse IgG2b Isotype Control for In Vivo - Low Endotoxin [MPC-11] (ICH2250)
Related Antibody :
Anti-CD20 In Vivo Antibody - Ultra Low Endotoxin [2H7] (ICH1012UL)
Use :
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
价格说明 :
Contact for industrial pricing
更多信息或购买 :
ichorbio 产品网页
公司信息
ichorbio
Grove Business Park
Downsview Road
Wantage OX12 9FF
hello@ichor.bio
https://www.ichor.bio
公司总部: 英国