产品简要
公司名称 :
ichorbio
产品类型 :
抗体
产品名称 :
Anti-EGFR In Vivo Antibody - Ultra Low Endotoxin (EGFR.1) [ICH1021UL] ichorbio
目录 :
ICH1021UL
规格 :
5毫克
价格 :
312 GBP
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
表皮生长因子受体.1
反应物种 :
人类
应用 :
免疫印迹
更多信息或购买 :
产品信息
产品类型 :
Ultra Low Endotoxin
ichorbio Cat Number :
ICH1021UL
Page Title :
Anti-EGFR In Vivo Antibody - Ultra Low Endotoxin (EGFR.1) [ICH1021UL] ichorbio
Page Heading :
Anti-EGFR In Vivo Antibody - Ultra Low Endotoxin (EGFR.1) [ICH1021UL]
Page Heading :
Bulk anti-EGFR In Vivo Antibody - Ultra Low Endotoxin (EGFR.1)
Product Benefits :
ichorbio's anti-EGFR In Vivo Antibody - Ultra Low Endotoxin (EGFR.1) is manufactured in a cGMP compliant, ISO Quality Standard 9001:2015 facility. This means that ichorbio's ultra low-endoxin antibodies have the lowest endotoxin in the industry at less than 0.75 EU/mg. The purity of ichorbio's ultra low endotoxin antibodies are unsurpassed at >98% and they are all pathogen tested and third-party certified by IDEXX BioReseach of meet the lowest mycoplasma specification and free of any viral pathogens of concern. ichorbio offers Amazon vouchers or donations to the NC3Rs for reviews of this product: click here for more information. ichorbio: the best antibodies for in vivo research.
靶标 :
表皮生长因子受体
克隆 :
表皮生长因子受体.1
尺寸1 :
5毫克
Academic Price1 :
312 GBP
尺寸2 :
25mg
Academic Price2 :
832
Size3 :
50mg
Academic Price3 :
1352
Size4 :
100mg
Academic Price4 :
2080
抗体亚型 :
小鼠IgG2b
其他名称 :
Epidermal growth factor receptor, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1, ERBB, ERBB1, HER1
UniProt数据库 :
P00533
宿主 :
小鼠
物种活性 :
人类
特异性 :
Anti-EGFR In Vivo Antibody - Ultra Low Endotoxin (EGFR.1) recognizes an epitope on Human EGFR
纯化方法 :
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
背景 :
The epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR (ErbB-1), HER2/c-neu (ErbB-2), Her 3 (ErbB-3) and Her 4 (ErbB-4). Mutations affecting EGFR expression or activity could result in cancer. EGFR (epidermal growth factor receptor) exists on the cell surface and is activated by binding of its specific ligands, including epidermal growth factor and transforming growth factor A (TGFA) (note, a full list of the ligands able to activate EGFR and other members of the ErbB family is given in the ErbB article). ErbB2 has no known direct activating ligand, and may be in an activated state constitutively or become active upon heterodimerization with other family members such as EGFR. Upon activation by its growth factor ligands, EGFR undergoes a transition from an inactive monomeric form to an active homodimer - although there is some evidence that preformed inactive dimers may also exist before ligand binding. In addition to forming homodimers after ligand binding, EGFR may pair with another member of the ErbB receptor family, such as ErbB2/Her2/neu, to create an activated heterodimer. There is also evidence to suggest that clusters of activated EGFRs form, although it remains unclear whether this clustering is important for activation itself or occurs subsequent to activation of individual dimers.
免疫原 :
A431培养细胞
浓度 :
1.0-5.0毫克/毫升
配方 :
0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added. BSA and Azide free.
纯度 :
>98% by SDS-PAGE and HPLC
内毒素 :
≤ 0.75 EU/mg as determined by the LAL method
Aggregation :
Aggregation level ≤ 1%
IMPACT Pathogen Test :
We use the IMPACT test generated by IDEXX Laboratories to guarantee our Ultra Low Endotoxin antibodies are pathogen free. Our mouse antibodies are tested for: Mycoplasma spp. Mycoplasma pulmonis Sendai virus Mouse hepatitis virus Pneumonia virus of mice Minute virus of mice Mouse parvovirus (MPV1-5) Theiler's murine encephalomyelitis virus Murine norovirus Reovirus 3 Mouse rotavirus Ectromelia virus Lymphocytic choriomeningitis virus Polyoma virus Lactate dehydrogenase-elevating virus Mouse adenovirus (MAD1, MAD2) Mouse cytomegalovirus K virus Mouse thymic virus Hantaan virus Corynebacterium bovis Corynebacterium spp. (HAC2)
储存 :
anti-EGFR In Vivo Antibody - Ultra Low Endotoxin (EGFR.1) is stable when stored at 2-8°C. Do not freeze.
应用 :
免疫印迹
应用注释 :
Each investigator should determine their own optimal working dilution for specific applications.
Isotype Control :
Mouse IgG2b Isotype Control for In Vivo - Ultra Low Endotoxin [MPC-11] (ICH2250UL)
Related Antibody :
Anti-EGFR In Vivo Antibody - Low Endotoxin [EGFR.1] (ICH1021)
Use :
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
价格说明 :
Contact for industrial pricing
更多信息或购买 :
公司信息
ichorbio
Grove Business Park
Downsview Road
Wantage OX12 9FF
hello@ichor.bio
https://www.ichor.bio
公司总部: 英国