产品简要
公司名称 :
ichorbio
产品类型 :
抗体
产品名称 :
Anti-CD119 In Vivo Antibody - Low Endotoxin (GIR 208) [ICH1028] ichorbio
目录 :
ICH1028
规格 :
1毫克
价格 :
80 GBP
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
GIR 208
反应物种 :
人类
应用 :
免疫印迹, 免疫沉淀
更多信息或购买 :
ichorbio 产品网页
产品信息
产品类型 :
低内毒素
ichorbio Cat Number :
ICH1028
Page Title :
Anti-CD119 In Vivo Antibody - Low Endotoxin (GIR 208) [ICH1028] ichorbio
Page Heading :
Anti-CD119 In Vivo Antibody - Low Endotoxin (GIR 208) [ICH1028]
Page Heading :
Bulk anti-CD119 In Vivo Antibody - Low Endotoxin (GIR 208)
Product Benefits :
ichorbio's anti-CD119 In Vivo Antibody - Low Endotoxin (GIR 208) is manufactured in a cGMP compliant, ISO Quality Standard 9001:2015 facility. ichorbio's low endotoxin antibodies have half the endotoxin of comparable antibodies from our competitors at less than 1.0 EU/mg. If ichorbio's low endotoxin antibodies are not low enough we also offer ultra low endotoxin antibodies which have even less endotoxin ( here for more information. ichorbio: the best antibodies for in vivo research.
靶标 :
CD119
克隆 :
GIR 208
尺寸1 :
1毫克
Academic Price1 :
80 GBP
尺寸2 :
5mg
Academic Price2 :
240
Size3 :
25mg
Academic Price3 :
640
Size4 :
50mg
Academic Price4 :
1040
Size5 :
100mg
Academic Price5 :
1600
抗体亚型 :
小鼠IgG1
其他名称 :
干扰素丙受体1, IFN丙受体1, IFN丙, CDw119, 干扰素丙受体甲chain2, IFN丙
UniProt数据库 :
P15260
宿主 :
小鼠
物种活性 :
人类
特异性 :
Anti-CD119 In Vivo Antibody - Low Endotoxin (GIR 208) recognizes Human IFN gamma R alpha
纯化方法 :
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Antigen Distribution :
The IFN-gamma receptor is expressed at moderate levels on virtually every cell with the exception of erythrocytes.
背景 :
Interferon-gamma (IFN-gamma) exerts its biologic effects by interacting with a single high affinity receptor, IFN-gamma receptor. This receptor is present on almost all cell types except mature erythrocytes. The IFN-gamma receptor consists of two polypeptide chains alpha and beta and requires association of JAK1, JAK2 and Stat1 for IFN-gamma signal transduction. In signal transduction, IFN-gamma induces tyrosine phosphorylation of IFN-gamma receptor alpha (IFNGR1) leading to the formation of a docking site on the activated receptor for Stat1, which specifically activates IFN-gamma induced gene transcription. The IFN-gamma receptor is structurally related to the recently cloned IL-10 receptor. GIR 208 binds IFNGR1 and blocks binding of IFN-gamma to the receptor.
免疫原 :
人类IFN丙R甲, 纯化来自人类胎盘
浓度 :
1.0-5.0毫克/毫升
配方 :
0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added. BSA and Azide free.
纯度 :
>95% by SDS-PAGE and HPLC
内毒素 :
≤ 1.0 EU/mg as determined by the LAL method
Aggregation :
Aggregation level ≤ 5%
储存 :
anti-CD119 In Vivo Antibody - Low Endotoxin (GIR 208) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
应用 :
免疫沉淀, 免疫印迹
应用注释 :
Each investigator should determine their own optimal working dilution for specific applications.
Isotype Control :
Mouse IgG1 Isotype Control for In Vivo - Low Endotoxin [HKSP] (ICH2247)
Related Antibody :
Anti-CD119 In Vivo Antibody - Ultra Low Endotoxin [GIR 208] (ICH1028UL)
Use :
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
价格说明 :
Contact for industrial pricing
更多信息或购买 :
ichorbio 产品网页
公司信息
ichorbio
Grove Business Park
Downsview Road
Wantage OX12 9FF
hello@ichor.bio
https://www.ichor.bio
公司总部: 英国