产品简要
公司名称 :
ichorbio
产品类型 :
抗体
产品名称 :
Anti-CD278 In Vivo Antibody - Low Endotoxin (7E.17G9) [ICH1082] ichorbio
目录 :
ICH1082
规格 :
1毫克
价格 :
80 GBP
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
未共轭
克隆名称 :
7E.17G9
反应物种 :
小鼠
应用 :
免疫印迹, 中和反应
更多信息或购买 :
产品信息
产品类型 :
低内毒素
ichorbio Cat Number :
ICH1082
Page Title :
Anti-CD278 In Vivo Antibody - Low Endotoxin (7E.17G9) [ICH1082] ichorbio
Page Heading :
Anti-CD278 In Vivo Antibody - Low Endotoxin (7E.17G9) [ICH1082]
Page Heading :
Bulk anti-CD278 In Vivo Antibody - Low Endotoxin (7E.17G9)
Product Benefits :
ichorbio's anti-CD278 In Vivo Antibody - Low Endotoxin (7E.17G9) is manufactured in a cGMP compliant, ISO Quality Standard 9001:2015 facility. ichorbio's low endotoxin antibodies have half the endotoxin of comparable antibodies from our competitors at less than 1.0 EU/mg. If ichorbio's low endotoxin antibodies are not low enough we also offer ultra low endotoxin antibodies which have even less endotoxin ( here for more information. ichorbio: the best antibodies for in vivo research.
靶标 :
CD278
克隆 :
7E.17G9
尺寸1 :
1毫克
Academic Price1 :
80 GBP
尺寸2 :
5mg
Academic Price2 :
240
Size3 :
25mg
Academic Price3 :
640
Size4 :
50mg
Academic Price4 :
1040
Size5 :
100mg
Academic Price5 :
1600
抗体亚型 :
大鼠IgG2b
其他名称 :
Inducible T-cell costimulator, Icos, Activation-inducible lymphocyte immunomediatory molecule, CD28 and CTLA-4-like protein, CCLP, CD28-related protein 1, CRP-1, Ailim
UniProt数据库 :
Q9WVS0
宿主 :
大鼠
物种活性 :
小鼠
特异性 :
Anti-CD278 In Vivo Antibody - Low Endotoxin (7E.17G9) recognizes an epitope on Mouse ICOS
纯化方法 :
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
背景 :
Inducible co-stimulator (ICOS), also called ALIM and H4, is a homodimeric protein and member of the CD28 family of immune co-stimulatory receptors. Other family members are CD28, CTLA-4 and PD-1. ICOS enhances all basic T cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B cells. Unlike the constitutively expressed CD28, ICOS has to be de novo induced on the T cell surface, does not up-regulate the production of IL-2, but superinduces the synthesis of IL-10, a B cell-differentiation factor. In vivo, ICOS is highly expressed on tonsillar T cells, which are closely associated with B cells in the apical light zone of germinal centres, the site of terminal B cell maturation. ICOS regulates CD28-dependent and CD28-independent CD4 (+) subset (Th1 and Th2) responses. It is a major regulator of the adaptive immune system and therefore, has a protective role in inflammatory autoimmune diseases.
浓度 :
1.0-5.0毫克/毫升
配方 :
0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added. BSA and Azide free.
纯度 :
>95% by SDS-PAGE and HPLC
内毒素 :
≤ 1.0 EU/mg as determined by the LAL method
Aggregation :
Aggregation level ≤ 5%
储存 :
anti-CD278 In Vivo Antibody - Low Endotoxin (7E.17G9) is stable when stored at 2-8°C. Do not freeze. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
应用 :
Western Blot, Blocking, Functional Assays
应用注释 :
Each investigator should determine their own optimal working dilution for specific applications.
Isotype Control :
Rat IgG2b In Vivo Isotype Control - Low Endotoxin [1-2] (ICH2243)
Related Antibody :
Anti-CD278 In Vivo Antibody - Ultra Low Endotoxin [7E.17G9] (ICH1082UL)
Use :
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
价格说明 :
Contact for industrial pricing
更多信息或购买 :
公司信息
ichorbio
Grove Business Park
Downsview Road
Wantage OX12 9FF
hello@ichor.bio
https://www.ichor.bio
公司总部: 英国