Anti-IL-4 In Vivo Antibody - Low Endotoxin (11B11) [ICH1087] ichorbio

产品简要

公司名称 :

ichorbio

产品类型 :

抗体

产品名称 :

Anti-IL-4 In Vivo Antibody - Low Endotoxin (11B11) [ICH1087] ichorbio

ICH1087

规格 :

0.5毫克

价格 :

160 GBP

克隆性 :

单克隆

宿主 :

大鼠

共轭标签 :

未共轭

克隆名称 :

11B11

反应物种 :

小鼠

应用 :

酶联免疫吸附测定, 中和反应, 免疫沉淀, 流式细胞仪

更多信息或购买 :

ichorbio 产品网页

产品信息

产品类型 :

低内毒素

ichorbio Cat Number :

ICH1087

Page Title :

Anti-IL-4 In Vivo Antibody - Low Endotoxin (11B11) [ICH1087] ichorbio

Page Heading :

Anti-IL-4 In Vivo Antibody - Low Endotoxin (11B11) [ICH1087]

Page Heading :

Bulk anti-IL-4 In Vivo Antibody - Low Endotoxin (11B11)

Product Benefits :

ichorbio's anti-IL-4 In Vivo Antibody - Low Endotoxin (11B11) is manufactured in a cGMP compliant, ISO Quality Standard 9001:2015 facility. ichorbio's low endotoxin antibodies have half the endotoxin of comparable antibodies from our competitors at less than 1.0 EU/mg. If ichorbio's low endotoxin antibodies are not low enough we also offer ultra low endotoxin antibodies which have even less endotoxin ( here for more information. ichorbio: the best antibodies for in vivo research.

靶标 :

IL-4

克隆 :

11B11

尺寸1 :

0.5毫克

Academic Price1 :

160 GBP

抗体亚型 :

大鼠IgG1

其他名称 :

Interleukin-4, Il-4, B-cell IgG differentiation factor, B-cell growth factor 1, B-cell stimulatory factor 1, BSF-1, IGG1 induction factor, Lymphocyte stimulatory factor 1

UniProt数据库 :

P07750

宿主 :

大鼠

物种活性 :

小鼠

特异性 :

Anti-IL-4 In Vivo Antibody - Low Endotoxin (11B11) recognizes an epitope on Mouse IL-4

纯化方法 :

This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

背景 :

Interleukin-4 (IL-4) is a pleiotropic immune cytokine secreted by activated TH2 cells that inhibits bone resorption. IL-4 is critical for inducing allergic responses. It has many biological roles, including the stimulation of activated B-cell and T-cell proliferation, and the differentiation of CD4+ T-cells into Th2 cells. It is also a key regulator in humoral and adaptive immunity. IL-4 is required for the pathogenesis of atopic diseases and immune regulation.

免疫原 :

Purified Recombinant Mouse IL-4 (>98%)

浓度 :

1.0-5.0毫克/毫升

配方 :

0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added. BSA and Azide free.

纯度 :

>95% by SDS-PAGE and HPLC

内毒素 :

<0.5 EU/mg as determined by the LAL method

Aggregation :

Aggregation level ≤ 5%

储存 :

anti-IL-4 In Vivo Antibody - Low Endotoxin (11B11) is stable when stored at 2-8°C for 1 week. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.

应用 :

ELISA Capture, ELISPOT, Flow Cytometry, Neutralization, Immunoprecipitation, Functional Assays

应用注释 :

ELISA Sandwich: This antibody is useful as the capture antibody in a sandwich ELISA. The suggested coating concentration is 0.5-2.0 µg/ml. ELISPOT Capture: This Low Endotoxin Functional Formulation antibody has been reported for use as the capture antibody in a sandwich ELISPOT assay. Aseptically coat plates at a concentration of 2-6 µg/ml is recommended. Neutralization: Anti-Mouse IL-4 (clone 11B11) antibody can neutralize the bioactivity of natural or recombinant IL-4. The Low Endotoxin Functional Formulation purified antibody (Endotoxin <0.1 EU/μg, Azide-Free, 0.2 μm filtered) is recommended for neutralization of mouse IL-4 bioactivity in vivo. Each investigator should determine their own optimal working dilution for specific applications.

Isotype Control :

Rat IgG1 Isotype Control for In Vivo - Low Endotoxin [GL113] (ICH2246)

Antibodies against the same target :

Anti-IL-4 In Vivo Antibody - Low Endotoxin [BVD6-24G2] (ICH1102) , Anti-IL-4 In Vivo Antibody - Low Endotoxin [MP4-25D2] (ICH1030)

Use :

Products are for research use only. Not for use in diagnostic or therapeutic procedures.

价格说明 :

Contact for industrial pricing

更多信息或购买 :

ichorbio 产品网页

公司信息