产品简要
公司名称 :
ichorbio
产品类型 :
抗体
产品名称 :
Anti-IL-1b In Vivo Antibody - Low Endotoxin (B122) [ICH1100] ichorbio
目录 :
ICH1100
规格 :
1毫克
价格 :
80 GBP
克隆性 :
单克隆
宿主 :
仓鼠
共轭标签 :
未共轭
克隆名称 :
B122
反应物种 :
小鼠
应用 :
免疫印迹, 中和反应, 免疫沉淀
更多信息或购买 :
ichorbio 产品网页
产品信息
产品类型 :
低内毒素
ichorbio Cat Number :
ICH1100
Page Title :
Anti-IL-1b In Vivo Antibody - Low Endotoxin (B122) [ICH1100] ichorbio
Page Heading :
Anti-IL-1b In Vivo Antibody - Low Endotoxin (B122) [ICH1100]
Page Heading :
Bulk anti-IL-1b In Vivo Antibody - Low Endotoxin (B122)
Product Benefits :
ichorbio's anti-IL-1b In Vivo Antibody - Low Endotoxin (B122) is manufactured in a cGMP compliant, ISO Quality Standard 9001:2015 facility. ichorbio's low endotoxin antibodies have half the endotoxin of comparable antibodies from our competitors at less than 1.0 EU/mg. If ichorbio's low endotoxin antibodies are not low enough we also offer ultra low endotoxin antibodies which have even less endotoxin ( here for more information. ichorbio: the best antibodies for in vivo research.
靶标 :
IL-1b
克隆 :
B122
尺寸1 :
1毫克
Academic Price1 :
80 GBP
尺寸2 :
5mg
Academic Price2 :
240
Size3 :
25mg
Academic Price3 :
640
Size4 :
50mg
Academic Price4 :
1040
Size5 :
100mg
Academic Price5 :
1600
抗体亚型 :
亚美尼亚仓鼠IgG
其他名称 :
白细胞介素1β, IL-1B
UniProt数据库 :
P10749
宿主 :
亚美尼亚仓鼠
物种活性 :
小鼠
特异性 :
Anti-IL-1b In Vivo Antibody - Low Endotoxin (B122) recognizes Mouse IL-1B
纯化方法 :
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Antigen Distribution :
Monocytes, tissue macrophages, Langerhan cells, dendritic cells, T lymphocytes, B lymphocytes, natural killer (NK) cells and many other B cells, T cells, related monocytes
背景 :
Interleukin 1 beta (IL1 beta) is a proinflammatory cytokine belonging to IL1 family that is synthesized as a precursor. The IL1 beta precursor form is not biologically active. It is expressed mainly by stimulated macrophages and monocytes. IL1 beta is known to be a mediator in inflammatory response and to be involved in a variety of cellular activities, proliferation, differentiation and apoptosis. It has been recently found that IL1 beta is a major cause of severe inflammation in the mouse model of Crohns disease which makes IL1 beta an important target for this disease. The B122 antibody has been reported to neutralize the bioactivity of natural or recombinant IL-1β.
免疫原 :
E. coli -expressed, recombinant mouse IL-1β
浓度 :
1.0毫克/毫升
配方 :
0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added. BSA and Azide free.
纯度 :
>95% by SDS-PAGE and HPLC
内毒素 :
≤ 1.0 EU/mg as determined by the LAL method
Aggregation :
Aggregation level ≤ 5%
储存 :
anti-IL-1b In Vivo Antibody - Low Endotoxin (B122) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
应用 :
中和反应, 免疫沉淀, 免疫印迹
应用注释 :
Each investigator should determine their own optimal working dilution for specific applications.
Isotype Control :
Armenian Hamster IgG Isotype Control for In Vivo - Low Endotoxin [PIP] (ICH2251)
Use :
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
价格说明 :
Contact for industrial pricing
更多信息或购买 :
ichorbio 产品网页
公司信息
ichorbio
Grove Business Park
Downsview Road
Wantage OX12 9FF
hello@ichor.bio
https://www.ichor.bio
公司总部: 英国