产品简要
公司名称 :
ichorbio
产品类型 :
抗体
产品名称 :
Anti-IFN beta In Vivo Antibody - Ultra Low Endotoxin (HDB-4A7) [ICH1110UL] ichorbio
目录 :
ICH1110UL
规格 :
5毫克
价格 :
312 GBP
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
HDB-4A7
应用 :
免疫印迹, 中和反应
更多信息或购买 :
ichorbio 产品网页
产品信息
产品类型 :
Ultra Low Endotoxin
ichorbio Cat Number :
ICH1110UL
Page Title :
Anti-IFN beta In Vivo Antibody - Ultra Low Endotoxin (HDB-4A7) [ICH1110UL] ichorbio
Page Heading :
Anti-IFN beta In Vivo Antibody - Ultra Low Endotoxin (HDB-4A7) [ICH1110UL]
Page Heading :
Bulk anti-IFN beta In Vivo Antibody - Ultra Low Endotoxin (HDB-4A7)
Product Benefits :
ichorbio's anti-IFN beta In Vivo Antibody - Ultra Low Endotoxin (HDB-4A7) is manufactured in a cGMP compliant, ISO Quality Standard 9001:2015 facility. This means that ichorbio's ultra low-endoxin antibodies have the lowest endotoxin in the industry at less than 0.75 EU/mg. The purity of ichorbio's ultra low endotoxin antibodies are unsurpassed at >98% and they are all pathogen tested and third-party certified by IDEXX BioReseach of meet the lowest mycoplasma specification and free of any viral pathogens of concern. ichorbio offers Amazon vouchers or donations to the NC3Rs for reviews of this product: click here for more information. ichorbio: the best antibodies for in vivo research.
靶标 :
IFN乙
克隆 :
HDB-4A7
尺寸1 :
5毫克
Academic Price1 :
312 GBP
尺寸2 :
25mg
Academic Price2 :
832
Size3 :
50mg
Academic Price3 :
1352
Size4 :
100mg
Academic Price4 :
2080
抗体亚型 :
小鼠IgG2a
其他名称 :
IFN-b, IFN乙, 类型1干扰素, 干扰素β
宿主 :
小鼠
物种活性 :
小鼠
特异性 :
Anti-IFN beta In Vivo Antibody - Ultra Low Endotoxin (HDB-4A7) recognizes an epitope on Mouse IFN-beta and binds specifically to murine IFNbeta and does not bind murine IFNg or several different IFNa species (a-1,4,5 or 13); HDb-4A7 binds both recombinant and natural forms
纯化方法 :
This antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
免疫原 :
Plasmid DNA encoding murine IFNb
浓度 :
1.0-5.0毫克/毫升
配方 :
0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added. BSA and Azide free.
纯度 :
>98% by SDS-PAGE and HPLC
内毒素 :
≤ 0.75 EU/mg as determined by the LAL method
Aggregation :
Aggregation level ≤ 1%
IMPACT Pathogen Test :
We use the IMPACT test generated by IDEXX Laboratories to guarantee our Ultra Low Endotoxin antibodies are pathogen free. Our mouse antibodies are tested for: Mycoplasma spp. Mycoplasma pulmonis Sendai virus Mouse hepatitis virus Pneumonia virus of mice Minute virus of mice Mouse parvovirus (MPV1-5) Theiler's murine encephalomyelitis virus Murine norovirus Reovirus 3 Mouse rotavirus Ectromelia virus Lymphocytic choriomeningitis virus Polyoma virus Lactate dehydrogenase-elevating virus Mouse adenovirus (MAD1, MAD2) Mouse cytomegalovirus K virus Mouse thymic virus Hantaan virus Corynebacterium bovis Corynebacterium spp. (HAC2)
储存 :
anti-IFN beta In Vivo Antibody - Ultra Low Endotoxin (HDB-4A7) is stable when stored at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
应用 :
Western Blot, Blocking, Functional Assays
应用注释 :
Functional Assay: In Vitro Activity of HDB-4A7 - inhibits IFNb-induced Stat1 phosphorylation (level of inhibition is similar to that seen using anti-IFNAR1 mAb (MAR1-5A3). - blocks IFNb induction of MHC-I expression (H2-Kb) using L929 or fibrosarcoma cell lines. - neutralizes IFNb-induced antiviral activity in vitro following infection of L929 cells with VSV In Vivo Activity of HDB-4A7 - circulates with a half-life of ~ 14 days. - blocks in vivo IFNb leading to increased the lethality of mice infected with West Nile Virus (WNV), similar to susceptibility of IFNb-/- mice. Each investigator should determine their own optimal working dilution for specific applications.
Isotype Control :
Mouse IgG2a In Vivo Isotype Control - Ultra Low Endotoxin [C1.18.4] (ICH2245UL)
Related Antibody :
Anti-IFN beta In Vivo Antibody - Low Endotoxin [HDB-4A7] (ICH1110)
Use :
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
价格说明 :
Contact for industrial pricing
更多信息或购买 :
ichorbio 产品网页
公司信息
ichorbio
Grove Business Park
Downsview Road
Wantage OX12 9FF
hello@ichor.bio
https://www.ichor.bio
公司总部: 英国