Anti-IL-6 In Vivo Antibody - Low Endotoxin (MP5-20F3) [ICH1126] ichorbio

产品简要

公司名称 :

ichorbio

产品类型 :

抗体

产品名称 :

Anti-IL-6 In Vivo Antibody - Low Endotoxin (MP5-20F3) [ICH1126] ichorbio

ICH1126

规格 :

0.5毫克

价格 :

160 GBP

克隆性 :

单克隆

宿主 :

大鼠

共轭标签 :

未共轭

克隆名称 :

MP5-20F3

反应物种 :

小鼠

应用 :

酶联免疫吸附测定, 中和反应

更多信息或购买 :

ichorbio 产品网页

产品信息

产品类型 :

低内毒素

ichorbio Cat Number :

ICH1126

Page Title :

Anti-IL-6 In Vivo Antibody - Low Endotoxin (MP5-20F3) [ICH1126] ichorbio

Page Heading :

Anti-IL-6 In Vivo Antibody - Low Endotoxin (MP5-20F3) [ICH1126]

Page Heading :

Bulk anti-IL-6 In Vivo Antibody - Low Endotoxin (MP5-20F3)

Product Benefits :

ichorbio's anti-IL-6 In Vivo Antibody - Low Endotoxin (MP5-20F3) is manufactured in a cGMP compliant, ISO Quality Standard 9001:2015 facility. ichorbio's low endotoxin antibodies have half the endotoxin of comparable antibodies from our competitors at less than 1.0 EU/mg. If ichorbio's low endotoxin antibodies are not low enough we also offer ultra low endotoxin antibodies which have even less endotoxin ( here for more information. ichorbio: the best antibodies for in vivo research.

靶标 :

IL-6

克隆 :

MP5-20F3

尺寸1 :

0.5毫克

Academic Price1 :

160 GBP

抗体亚型 :

大鼠IgG1

其他名称 :

白细胞介素6, IL-6, B细胞杂交瘤细胞生长因子, 白细胞介素HP-1

UniProt数据库 :

P08505

宿主 :

大鼠

物种活性 :

小鼠

特异性 :

Anti-IL-6 In Vivo Antibody - Low Endotoxin (MP5-20F3) recognizes an epitope on Mouse IL-6

纯化方法 :

This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

背景 :

Interleukin-6 (IL-6) is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine. It is secreted by T cells and macrophages to stimulate immune response to trauma, especially burns or other tissue damage leading to inflammation. IL-6 is also a "myokine," a cytokine produced from muscle, and is elevated in response to muscle contraction. It is significantly elevated with exercise, and precedes the appearance of other cytokines in the circulation. Additionally, osteoblasts secrete IL-6 to stimulate osteoclast formation. Smooth muscle cells in the tunica media of many blood vessels also produce IL-6 as a pro-inflammatory cytokine. IL-6's role as an anti-inflammatory cytokine is mediated through its inhibitory effects on TNF-alpha and IL-1, and activation of IL-1ra and IL-10. IL16 has been shown to suppress the replication of HIV and SIV.

浓度 :

1.0毫克/毫升

配方 :

0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added. BSA and Azide free.

纯度 :

>95% by SDS-PAGE and HPLC

内毒素 :

<0.1 EU/mg as determined by the LAL method

Aggregation :

Aggregation level ≤ 5%

储存 :

anti-IL-6 In Vivo Antibody - Low Endotoxin (MP5-20F3) is stable when stored at 2-8°C. Do not freeze. For long term storage, aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.

应用 :

ELISA Capture, ELISPOT, Neutralization, Functional Assays

应用注释 :

ELISA Sandwich: This antibody is useful as the capture antibody in a sandwich ELISA. A suitable detection antibody is at a concentration of approximately 0.5-2 ug/mL µg/ml. Each investigator should determine their own optimal working dilution for specific applications.

Isotype Control :

Rat IgG1 Isotype Control for In Vivo - Low Endotoxin [GL113] (ICH2246)

Use :

Products are for research use only. Not for use in diagnostic or therapeutic procedures.

价格说明 :

Contact for industrial pricing

更多信息或购买 :

ichorbio 产品网页

公司信息