产品简要
公司名称 :
ichorbio
产品类型 :
抗体
产品名称 :
Anti-PD-1 In Vivo Antibody - Low Endotoxin (RMP1-14) [ICH1132] ichorbio
目录 :
ICH1132
规格 :
1毫克
价格 :
80 GBP
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
未共轭
克隆名称 :
RMP1-14
反应物种 :
小鼠
应用 :
免疫印迹, 中和反应
更多信息或购买 :
产品信息
产品类型 :
低内毒素
ichorbio Cat Number :
ICH1132
Page Title :
Anti-PD-1 In Vivo Antibody - Low Endotoxin (RMP1-14) [ICH1132] ichorbio
Page Heading :
Anti-PD-1 In Vivo Antibody - Low Endotoxin (RMP1-14) [ICH1132]
Page Heading :
Bulk anti-PD-1 In Vivo Antibody - Low Endotoxin (RMP1-14)
Product Benefits :
ichorbio's anti-PD-1 In Vivo Antibody - Low Endotoxin (RMP1-14) is manufactured in a cGMP compliant, ISO Quality Standard 9001:2015 facility. ichorbio's low endotoxin antibodies have half the endotoxin of comparable antibodies from our competitors at less than 1.0 EU/mg. If ichorbio's low endotoxin antibodies are not low enough we also offer ultra low endotoxin antibodies which have even less endotoxin ( here for more information. ichorbio: the best antibodies for in vivo research.
靶标 :
PD-1
克隆 :
RMP1-14
尺寸1 :
1毫克
Academic Price1 :
80 GBP
尺寸2 :
5mg
Academic Price2 :
240
Size3 :
25mg
Academic Price3 :
640
Size4 :
50mg
Academic Price4 :
1040
Size5 :
100mg
Academic Price5 :
1600
抗体亚型 :
大鼠IgG2a
其他名称 :
Programmed cell death protein 1, Pdcd1, CD279
UniProt数据库 :
Q02242
宿主 :
大鼠
物种活性 :
小鼠
特异性 :
Anti-PD-1 In Vivo Antibody - Low Endotoxin (RMP1-14) recognizes an epitope on Mouse PD-1
纯化方法 :
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Antigen Distribution :
Subset of double negative thymocytes, activated T and B cells
背景 :
CD279, also known as programmed death-1 (PD-1) is a 50-55 kD immunoglobulin superfamily member. PD-1 is expressed on a subset of CD4-CD8- thymocytes, and on activated T and B cells. The PD-1 ligands, PD-L1 (also known as B7-H1) and PD-L2 (B7-DC), are members of the B7 immunoglobulin superfamily. This RMP1-14 antibody has been reported to block the binding of PD-1 to its ligands (B7-H1 and B7-DC) and to inhibit T cell proliferation and cytokine production.
免疫原 :
Mouse PD-1 transfected BHK cells
浓度 :
1.0-5.0毫克/毫升
配方 :
0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added. BSA and Azide free.
纯度 :
>95% by SDS-PAGE and HPLC
内毒素 :
≤ 1.0 EU/mg as determined by the LAL method
Aggregation :
Aggregation level ≤ 5%
储存 :
anti-PD-1 In Vivo Antibody - Low Endotoxin (RMP1-14) is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -70oC.
应用 :
免疫印迹, 中和
应用注释 :
Blocking: Clone RMP1-14 antibody has been shown to block the binding of both mouse PD-L1-Ig and mouse PD-L2-Ig to PD-1. For immune checkpoint antibodies 200 ug per mouse per injection is the standard dosage in the literature. For this anti-PD-1 (clone RMP1-14), we suggest to inject 200 ug/mouse ip generally on days 3, 6 and 9, post injection of tumor. Sometime up to six injections depending on the length of the experiment may be required. Each investigator should determine their own optimal working dilution for specific applications.
Isotype Control :
Rat IgG2a In Vivo Isotype Control - Low Endotoxin [1-1] (ICH2244)
Related Antibody :
Anti-PD-1 In Vivo Antibody - Ultra Low Endotoxin [RMP1-14] (ICH1132UL)
Antibodies against the same target :
Anti-PD-1 In Vivo Antibody - Low Endotoxin [J43] (ICH1116) , Anti-PD-1 In Vivo Antibody - Low Endotoxin [29F.1A12] (ICH1091) , Anti-PD-1 In Vivo Antibody - Ultra Low Endotoxin [29F.1A12] (ICH1091UL)
Use :
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
价格说明 :
Contact for industrial pricing
更多信息或购买 :
公司信息
ichorbio
Grove Business Park
Downsview Road
Wantage OX12 9FF
hello@ichor.bio
https://www.ichor.bio
公司总部: 英国