Moore T, Cheng L, Wolf D, Ngo J, Segawa M, Zhu X, et al. Parkin regulates adiposity by coordinating mitophagy with mitochondrial biogenesis in white adipocytes. Nat Commun. 2022;13:6661 pubmed 出版商

Ye G, Xu M, Shu Y, Sun X, Mai Y, Hong Y, et al. A Quassinoid Diterpenoid Eurycomanone from Eurycoma longifolia Jack Exerts Anti-Cancer Effect through Autophagy Inhibition. Molecules. 2022;27: pubmed 出版商

Sumi K, Hatanaka Y, Takahashi R, Wada N, Ono C, Sakamoto Y, et al. Citrate Synthase Insufficiency Leads to Specific Metabolic Adaptations in the Heart and Skeletal Muscles Upon Low-Carbohydrate Diet Feeding in Mice. Front Nutr. 2022;9:925908 pubmed 出版商

Yang C, Su C, Iyaswamy A, Krishnamoorthi S, Zhu Z, Yang S, et al. Celastrol enhances transcription factor EB (TFEB)-mediated autophagy and mitigates Tau pathology: Implications for Alzheimer's disease therapy. Acta Pharm Sin B. 2022;12:1707-1722 pubmed 出版商

Pillai S, Mahmud I, Mahar R, Griffith C, Langsen M, Nguyen J, et al. Lipogenesis mediated by OGR1 regulates metabolic adaptation to acid stress in cancer cells via autophagy. Cell Rep. 2022;39:110796 pubmed 出版商

Wu P, Li Y, Cai M, Ye B, Geng B, Li F, et al. Ubiquitin Carboxyl-Terminal Hydrolase L1 of Cardiomyocytes Promotes Macroautophagy and Proteostasis and Protects Against Post-myocardial Infarction Cardiac Remodeling and Heart Failure. Front Cardiovasc Med. 2022;9:866901 pubmed 出版商

Andr xe9 s Benito P, Carmona M, Jord xe1 n M, Fern xe1 ndez Irigoyen J, Santamar xed a E, Del Rio J, et al. Host Tau Genotype Specifically Designs and Regulates Tau Seeding and Spreading and Host Tau Transformation Following Intrahippocampal Injection of Identical Tau AD Inoculum. Int J Mol Sci. 2022;23: pubmed 出版商

Hu Y, Qian Y, Wei J, Jin T, Kong X, Cao H, et al. The Disulfiram/Copper Complex Induces Autophagic Cell Death in Colorectal Cancer by Targeting ULK1. Front Pharmacol. 2021;12:752825 pubmed 出版商

Li M, Shen Y, Xiong Y, Wang S, Li C, Bai J, et al. Loss of SMARCB1 promotes autophagy and facilitates tumour progression in chordoma by transcriptionally activating ATG5. Cell Prolif. 2021;54:e13136 pubmed 出版商

Minton D, Elliehausen C, Javors M, Santangello K, Konopka A. Rapamycin-induced hyperglycemia is associated with exacerbated age-related osteoarthritis. Arthritis Res Ther. 2021;23:253 pubmed 出版商

Li R, Hao Y, Wang Q, Meng Y, Wu K, Liu C, et al. ECHS1, an interacting protein of LASP1, induces sphingolipid-metabolism imbalance to promote colorectal cancer progression by regulating ceramide glycosylation. Cell Death Dis. 2021;12:911 pubmed 出版商

Cao Y, Li Q, Yang Y, Ke Z, Chen S, Li M, et al. Cardioprotective Effect of Stem-Leaf Saponins From Panax notoginseng on Mice With Sleep Derivation by Inhibiting Abnormal Autophagy Through PI3K/Akt/mTOR Pathway. Front Cardiovasc Med. 2021;8:694219 pubmed 出版商

Shyam R, Ogando D, Choi M, Liton P, Bonanno J. Mitochondrial ROS Induced Lysosomal Dysfunction and Autophagy Impairment in an Animal Model of Congenital Hereditary Endothelial Dystrophy. Invest Ophthalmol Vis Sci. 2021;62:15 pubmed 出版商

Zeng H, Chen H, Li M, Zhuang J, Peng Y, Zhou H, et al. Autophagy protein NRBF2 attenuates endoplasmic reticulum stress-associated neuroinflammation and oxidative stress via promoting autophagosome maturation by interacting with Rab7 after SAH. J Neuroinflammation. 2021;18:210 pubmed 出版商

Shi Y, Hu Y, Wang Y, Ma X, Tang L, Tao M, et al. Blockade of Autophagy Prevents the Development and Progression of Peritoneal Fibrosis. Front Pharmacol. 2021;12:724141 pubmed 出版商

Hu D, Sun X, Magpusao A, Fedorov Y, Thompson M, Wang B, et al. Small-molecule suppression of calpastatin degradation reduces neuropathology in models of Huntington's disease. Nat Commun. 2021;12:5305 pubmed 出版商

Ashok A, Chaudhary S, Wise A, Rana N, McDonald D, Kritikos A, et al. Release of Iron-Loaded Ferritin in Sodium Iodate-Induced Model of Age Related Macular Degeneration: An In-Vitro and In-Vivo Study. Antioxidants (Basel). 2021;10: pubmed 出版商

Lee S, Chen Y, Chien C, Yan Y, Chen H, Chuang H, et al. Three month inhalation exposure to low-level PM2.5 induced brain toxicity in an Alzheimer's disease mouse model. PLoS ONE. 2021;16:e0254587 pubmed 出版商

Liu M, Shan M, Zhang Y, Guo Z. Progranulin Protects Against Airway Remodeling Through the Modulation of Autophagy via HMGB1 Suppression in House Dust Mite-Induced Chronic Asthma. J Inflamm Res. 2021;14:3891-3904 pubmed 出版商

Yuan T, Annamalai K, Naik S, Lupse B, Geravandi S, Pal A, et al. The Hippo kinase LATS2 impairs pancreatic β-cell survival in diabetes through the mTORC1-autophagy axis. Nat Commun. 2021;12:4928 pubmed 出版商

Silva Rojas R, Charles A, Djeddi S, Geny B, Laporte J, Böhm J. Pathophysiological Effects of Overactive STIM1 on Murine Muscle Function and Structure. Cells. 2021;10: pubmed 出版商

Yoon Y, Go G, Yoon S, Lim J, Lee G, Lee J, et al. Melatonin Treatment Improves Renal Fibrosis via miR-4516/SIAH3/PINK1 Axis. Cells. 2021;10: pubmed 出版商

Chen C, Wang S, Yu L, Mueller J, Fortunato F, Rausch V, et al. H2O2-mediated autophagy during ethanol metabolism. Redox Biol. 2021;46:102081 pubmed 出版商

Coudert L, Osseni A, Gangloff Y, Schaeffer L, Leblanc P. The ESCRT-0 subcomplex component Hrs/Hgs is a master regulator of myogenesis via modulation of signaling and degradation pathways. BMC Biol. 2021;19:153 pubmed 出版商

Liu H, Zang P, Lee I, Anderson B, Christiani A, Strait Bodey L, et al. Growth hormone secretagogue receptor-1a mediates ghrelin's effects on attenuating tumour-induced loss of muscle strength but not muscle mass. J Cachexia Sarcopenia Muscle. 2021;12:1280-1295 pubmed 出版商

Ding B, Bao C, Jin L, Xu L, Fan W, Lou W. CASK Silence Overcomes Sorafenib Resistance of Hepatocellular Carcinoma Through Activating Apoptosis and Autophagic Cell Death. Front Oncol. 2021;11:681683 pubmed 出版商

Amegandjin C, Choudhury M, Jadhav V, Carriço J, Quintal A, Berryer M, et al. Sensitive period for rescuing parvalbumin interneurons connectivity and social behavior deficits caused by TSC1 loss. Nat Commun. 2021;12:3653 pubmed 出版商

Hu F, Song D, Yan Y, Huang C, Shen C, Lan J, et al. IL-6 regulates autophagy and chemotherapy resistance by promoting BECN1 phosphorylation. Nat Commun. 2021;12:3651 pubmed 出版商

Wu Q, Tian A, Li B, Leduc M, Forveille S, Hamley P, et al. IGF1 receptor inhibition amplifies the effects of cancer drugs by autophagy and immune-dependent mechanisms. J Immunother Cancer. 2021;9: pubmed 出版商

Basse A, Agerholm M, Farup J, Dalbram E, Nielsen J, Ørtenblad N, et al. Nampt controls skeletal muscle development by maintaining Ca2+ homeostasis and mitochondrial integrity. Mol Metab. 2021;53:101271 pubmed 出版商

Ray U, Roy D, Jin L, Thirusangu P, Staub J, Xiao Y, et al. Group III phospholipase A2 downregulation attenuated survival and metastasis in ovarian cancer and promotes chemo-sensitization. J Exp Clin Cancer Res. 2021;40:182 pubmed 出版商

Urdiciain A, Erausquin E, Zelaya M, Zazpe I, Lanciego J, Melendez B, et al. Silencing of Histone Deacetylase 6 Decreases Cellular Malignancy and Contributes to Primary Cilium Restoration, Epithelial-to-Mesenchymal Transition Reversion, and Autophagy Inhibition in Glioblastoma Cell Lines. Biology (Basel). 2021;10: pubmed 出版商

Zhang L, He J, Wang J, Liu J, Chen Z, Deng B, et al. Knockout RAGE alleviates cardiac fibrosis through repressing endothelial-to-mesenchymal transition (EndMT) mediated by autophagy. Cell Death Dis. 2021;12:470 pubmed 出版商

Sighel D, Notarangelo M, Aibara S, Re A, Ricci G, Guida M, et al. Inhibition of mitochondrial translation suppresses glioblastoma stem cell growth. Cell Rep. 2021;35:109024 pubmed 出版商

Martínez Gutiérrez A, Fernández Duran I, Marazuela Duque A, Simonet N, Yousef I, Martínez Rovira I, et al. Shikimic acid protects skin cells from UV-induced senescence through activation of the NAD+-dependent deacetylase SIRT1. Aging (Albany NY). 2021;13:12308-12333 pubmed 出版商

Dong W, Zhang H, Zhao C, Luo Y, Chen Y. Silencing of miR-150-5p Ameliorates Diabetic Nephropathy by Targeting SIRT1/p53/AMPK Pathway. Front Physiol. 2021;12:624989 pubmed 出版商

Poon A, Saini H, Sethi S, O Sullivan G, Plun Favreau H, Wray S, et al. The role of SQSTM1 (p62) in mitochondrial function and clearance in human cortical neurons. Stem Cell Reports. 2021;16:1276-1289 pubmed 出版商

Caballero B, Bourdenx M, Luengo E, Díaz A, Sohn P, Chen X, et al. Acetylated tau inhibits chaperone-mediated autophagy and promotes tau pathology propagation in mice. Nat Commun. 2021;12:2238 pubmed 出版商

Chen Y, Wang R, Huang S, Henson E, Bi J, Gibson S. Erb-b2 Receptor Tyrosine Kinase 2 (ERBB2) Promotes ATG12-Dependent Autophagy Contributing to Treatment Resistance of Breast Cancer Cells. Cancers (Basel). 2021;13: pubmed 出版商

Van Alstyne M, Tattoli I, Delestrée N, Recinos Y, Workman E, Shihabuddin L, et al. Gain of toxic function by long-term AAV9-mediated SMN overexpression in the sensorimotor circuit. Nat Neurosci. 2021;24:930-940 pubmed 出版商

Tamargo Gómez I, Martínez García G, Suarez M, Rey V, Fueyo A, Codina Martínez H, et al. ATG4D is the main ATG8 delipidating enzyme in mammalian cells and protects against cerebellar neurodegeneration. Cell Death Differ. 2021;: pubmed 出版商

Tan A, PRASAD R, Jho E. TFEB regulates pluripotency transcriptional network in mouse embryonic stem cells independent of autophagy-lysosomal biogenesis. Cell Death Dis. 2021;12:343 pubmed 出版商

Frew J, Nygaard H. Neuropathological and behavioral characterization of aged Grn R493X progranulin-deficient frontotemporal dementia knockin mice. Acta Neuropathol Commun. 2021;9:57 pubmed 出版商

Liu X, Jiang J, Liao Y, Tang I, Zheng E, Qiu W, et al. Combination Chemo-Immunotherapy for Pancreatic Cancer Using the Immunogenic Effects of an Irinotecan Silicasome Nanocarrier Plus Anti-PD-1. Adv Sci (Weinh). 2021;8:2002147 pubmed 出版商

Shen Z, Ji K, Cai Z, Huang C, He X, Xu H, et al. Inhibition of HDAC6 by Tubastatin A reduces chondrocyte oxidative stress in chondrocytes and ameliorates mouse osteoarthritis by activating autophagy. Aging (Albany NY). 2021;13:9820-9837 pubmed 出版商

Cockey S, McFarland K, Koller E, Brooks M, Gonzalez De La Cruz E, Cruz P, et al. Il-10 signaling reduces survival in mouse models of synucleinopathy. NPJ Parkinsons Dis. 2021;7:30 pubmed 出版商

Zhang Y, Swanda R, Nie L, Liu X, Wang C, Lee H, et al. mTORC1 couples cyst(e)ine availability with GPX4 protein synthesis and ferroptosis regulation. Nat Commun. 2021;12:1589 pubmed 出版商

Wallace M, Aguirre N, Marcotte G, Marshall A, Baehr L, Hughes D, et al. The ketogenic diet preserves skeletal muscle with aging in mice. Aging Cell. 2021;20:e13322 pubmed 出版商

Li T, Yin Y, Mu N, Wang Y, Liu M, Chen M, et al. Metformin-Enhanced Cardiac AMP-Activated Protein Kinase/Atrogin-1 Pathways Inhibit Charged Multivesicular Body Protein 2B Accumulation in Ischemia-Reperfusion Injury. Front Cell Dev Biol. 2020;8:621509 pubmed 出版商

Ryan B, Bengoa Vergniory N, Williamson M, Kirkiz E, Roberts R, Corda G, et al. REST protects dopaminergic neurons from mitochondrial and α-synuclein oligomer pathology in an alpha synuclein overexpressing BAC-transgenic mouse model. J Neurosci. 2021;: pubmed 出版商

Xu S, Tao H, Cao W, Cao L, Lin Y, Zhao S, et al. Ketogenic diets inhibit mitochondrial biogenesis and induce cardiac fibrosis. Signal Transduct Target Ther. 2021;6:54 pubmed 出版商

Sweat M, Sweat Y, Yu W, Su D, Leonard R, Eliason S, et al. The miR-200 family is required for ectodermal organ development through the regulation of the epithelial stem cell niche. Stem Cells. 2021;39:761-775 pubmed 出版商

Affortit C, Casas F, Ladrech S, Ceccato J, Bourien J, Coyat C, et al. Exacerbated age-related hearing loss in mice lacking the p43 mitochondrial T3 receptor. BMC Biol. 2021;19:18 pubmed 出版商

Kong Y, Zhao X, Qiu M, Lin Y, Feng P, Li S, et al. Tubular Mas receptor mediates lipid-induced kidney injury. Cell Death Dis. 2021;12:110 pubmed 出版商

Choi G, Lee H, Chae C, Cho J, Jung Y, Kim J, et al. BNIP3L/NIX-mediated mitophagy protects against glucocorticoid-induced synapse defects. Nat Commun. 2021;12:487 pubmed 出版商

Schlein C, Fischer A, Sass F, Worthmann A, Tödter K, Jaeckstein M, et al. Endogenous Fatty Acid Synthesis Drives Brown Adipose Tissue Involution. Cell Rep. 2021;34:108624 pubmed 出版商

Stojakovic A, Trushin S, Sheu A, Khalili L, Chang S, Li X, et al. Partial inhibition of mitochondrial complex I ameliorates Alzheimer's disease pathology and cognition in APP/PS1 female mice. Commun Biol. 2021;4:61 pubmed 出版商

Polanco J, Hand G, Briner A, Li C, Götz J. Exosomes induce endolysosomal permeabilization as a gateway by which exosomal tau seeds escape into the cytosol. Acta Neuropathol. 2021;141:235-256 pubmed 出版商

Ao H, Li H, Zhao X, Liu B, Lu L. TXNIP positively regulates the autophagy and apoptosis in the rat müller cell of diabetic retinopathy. Life Sci. 2021;267:118988 pubmed 出版商

Zhou L, He R, Fang P, Li M, Yu H, Wang Q, et al. Hepatitis B virus rigs the cellular metabolome to avoid innate immune recognition. Nat Commun. 2021;12:98 pubmed 出版商

Tan C, Chang H, Zhou Q, Yu C, Fu N, Sabapathy K, et al. MOAP-1-mediated dissociation of p62/SQSTM1 bodies releases Keap1 and suppresses Nrf2 signaling. EMBO Rep. 2021;:e50854 pubmed 出版商

Zheng Q, Shen H, Tong Z, Cheng L, Xu Y, Feng Z, et al. A thermosensitive, reactive oxygen species-responsive, MR409-encapsulated hydrogel ameliorates disc degeneration in rats by inhibiting the secretory autophagy pathway. Theranostics. 2021;11:147-163 pubmed 出版商

Dong X, Yang Y, Zou Z, Zhao Y, Ci B, Zhong L, et al. Sorting nexin 5 mediates virus-induced autophagy and immunity. Nature. 2021;589:456-461 pubmed 出版商

Chung L, Liu S, Huang S, Salter D, Lee H, Hsu Y. High phosphate induces skeletal muscle atrophy and suppresses myogenic differentiation by increasing oxidative stress and activating Nrf2 signaling. Aging (Albany NY). 2020;12:21446-21468 pubmed 出版商

Zhang Y, Xu X, Hu M, Wang X, Cheng H, Zhou R. SPATA33 is an autophagy mediator for cargo selectivity in germline mitophagy. Cell Death Differ. 2021;28:1076-1090 pubmed 出版商

Tiwari S, Dang J, Lin N, Qin Y, Wang S, Rana T. Zika virus depletes neural stem cells and evades selective autophagy by suppressing the Fanconi anemia protein FANCC. EMBO Rep. 2020;:e49183 pubmed 出版商

Li Y, Ivica N, Dong T, Papageorgiou D, He Y, Brown D, et al. MFSD7C switches mitochondrial ATP synthesis to thermogenesis in response to heme. Nat Commun. 2020;11:4837 pubmed 出版商

Ogasawara Y, Cheng J, Tatematsu T, Uchida M, Murase O, Yoshikawa S, et al. Long-term autophagy is sustained by activation of CCTβ3 on lipid droplets. Nat Commun. 2020;11:4480 pubmed 出版商

Li Z, Zhang H, Huang Y, Huang J, Sun P, Zhou N, et al. Autophagy deficiency promotes triple-negative breast cancer resistance to T cell-mediated cytotoxicity by blocking tenascin-C degradation. Nat Commun. 2020;11:3806 pubmed 出版商

Lanzillotta C, Zuliani I, Vasavda C, Snyder S, Paul B, Perluigi M, et al. BVR-A Deficiency Leads to Autophagy Impairment through the Dysregulation of AMPK/mTOR Axis in the Brain-Implications for Neurodegeneration. Antioxidants (Basel). 2020;9: pubmed 出版商

Silva M, Nandi G, Tentarelli S, Gurrell I, Jamier T, Lucente D, et al. Prolonged tau clearance and stress vulnerability rescue by pharmacological activation of autophagy in tauopathy neurons. Nat Commun. 2020;11:3258 pubmed 出版商

Shen S, Li B, Dai J, Wu Z, He Y, Wen L, et al. BRD4 Inhibition Protects Against Acute Pancreatitis Through Restoring Impaired Autophagic Flux. Front Pharmacol. 2020;11:618 pubmed 出版商

Brattås P, Hersbach B, Madsen S, Petri R, Jakobsson J, Pircs K. Impact of differential and time-dependent autophagy activation on therapeutic efficacy in a model of Huntington disease. Autophagy. 2021;17:1316-1329 pubmed 出版商

Sozen E, Yazgan B, Tok O, Demirel T, Ercan F, Proto J, et al. Cholesterol induced autophagy via IRE1/JNK pathway promotes autophagic cell death in heart tissue. Metabolism. 2020;106:154205 pubmed 出版商

Mahameed M, Boukeileh S, Obiedat A, Darawshi O, Dipta P, Rimon A, et al. Pharmacological induction of selective endoplasmic reticulum retention as a strategy for cancer therapy. Nat Commun. 2020;11:1304 pubmed 出版商

Yan S, Ding H, Peng J, Wang X, Pang C, Wei J, et al. Down-regulation of protease-activated receptor 2 ameliorated osteoarthritis in rats through regulation of MAPK/NF-κB signaling pathway in vivo and in vitro. Biosci Rep. 2020;40: pubmed 出版商

Zhuang X, Wang S, Tan Y, Song J, Zhu Z, Wang Z, et al. Pharmacological enhancement of TFEB-mediated autophagy alleviated neuronal death in oxidative stress-induced Parkinson's disease models. Cell Death Dis. 2020;11:128 pubmed 出版商

Chávez M, Morales R, Lopez Crisosto C, Roa J, Allende M, Lavandero S. Autophagy Activation in Zebrafish Heart Regeneration. Sci Rep. 2020;10:2191 pubmed 出版商

Li J, Zhang W, Zhu S, Shi F. Nitric Oxide Synthase Is Involved in Follicular Development via the PI3K/AKT/FoxO3a Pathway in Neonatal and Immature Rats. Animals (Basel). 2020;10: pubmed 出版商

Nixon C, Mavigner M, Sampey G, Brooks A, Spagnuolo R, Irlbeck D, et al. Systemic HIV and SIV latency reversal via non-canonical NF-κB signalling in vivo. Nature. 2020;578:160-165 pubmed 出版商

Jo D, Park S, Kim A, Park N, Kim J, Bae J, et al. Loss of HSPA9 induces peroxisomal degradation by increasing pexophagy. Autophagy. 2020;:1-15 pubmed 出版商

Dai E, Han L, Liu J, Xie Y, Kroemer G, Klionsky D, et al. Autophagy-dependent ferroptosis drives tumor-associated macrophage polarization via release and uptake of oncogenic KRAS protein. Autophagy. 2020;:1-15 pubmed 出版商

Lieberman O, Frier M, McGuirt A, Griffey C, Rafikian E, Yang M, et al. Cell-type-specific regulation of neuronal intrinsic excitability by macroautophagy. elife. 2020;9: pubmed 出版商

Quach C, Song Y, Guo H, Li S, Maazi H, Fung M, et al. A truncating mutation in the autophagy gene UVRAG drives inflammation and tumorigenesis in mice. Nat Commun. 2019;10:5681 pubmed 出版商

Wu Y, Chen K, Xing G, Li L, Ma B, Hu Z, et al. Phospholipid remodeling is critical for stem cell pluripotency by facilitating mesenchymal-to-epithelial transition. Sci Adv. 2019;5:eaax7525 pubmed 出版商

Park S, Jeon P, Jun Y, Park J, Lee S, Lee S, et al. Monitoring LC3- or GABARAP-positive autophagic membranes using modified RavZ-based probes. Sci Rep. 2019;9:16593 pubmed 出版商

Shin H, Park H, Shin N, Kwon H, Yin Y, Hwang J, et al. Pink1-Mediated Chondrocytic Mitophagy Contributes to Cartilage Degeneration in Osteoarthritis. J Clin Med. 2019;8: pubmed 出版商

Chen G, Xie W, Nah J, Sauvat A, Liu P, Pietrocola F, et al. 3,4-Dimethoxychalcone induces autophagy through activation of the transcription factors TFE3 and TFEB. EMBO Mol Med. 2019;11:e10469 pubmed 出版商

Zhao X, Nedvetsky P, Stanchi F, Vion A, Popp O, Zühlke K, et al. Endothelial PKA activity regulates angiogenesis by limiting autophagy through phosphorylation of ATG16L1. elife. 2019;8: pubmed 出版商

di Meco A, Pratico D. Early-life exposure to high-fat diet influences brain health in aging mice. Aging Cell. 2019;18:e13040 pubmed 出版商

Martin Hurtado A, Martin Morales R, Robledinos Antón N, Blanco R, Palacios Blanco I, Lastres Becker I, et al. NRF2-dependent gene expression promotes ciliogenesis and Hedgehog signaling. Sci Rep. 2019;9:13896 pubmed 出版商

Oleinik N, Kim J, Roth B, Selvam S, Gooz M, Johnson R, et al. Mitochondrial protein import is regulated by p17/PERMIT to mediate lipid metabolism and cellular stress. Sci Adv. 2019;5:eaax1978 pubmed 出版商

Li J, Shi K, Sabet Z, Fu W, Zhou H, Xu S, et al. New power of self-assembling carbonic anhydrase inhibitor: Short peptide-constructed nanofibers inspire hypoxic cancer therapy. Sci Adv. 2019;5:eaax0937 pubmed 出版商

Tang C, Han H, Liu Z, Liu Y, Yin L, Cai J, et al. Activation of BNIP3-mediated mitophagy protects against renal ischemia-reperfusion injury. Cell Death Dis. 2019;10:677 pubmed 出版商

Zhang B, Chen H, Ouyang J, Xie Y, Chen L, Tan Q, et al. SQSTM1-dependent autophagic degradation of PKM2 inhibits the production of mature IL1B/IL-1β and contributes to LIPUS-mediated anti-inflammatory effect. Autophagy. 2019;:1-17 pubmed 出版商

Liu H, Feng X, Yang B, Tong R, Lu Y, Chen D, et al. Dimethyl fumarate suppresses hepatocellular carcinoma progression via activating SOCS3/JAK1/STAT3 signaling pathway. Am J Transl Res. 2019;11:4713-4725 pubmed

He R, Wang M, Zhao C, Shen M, Yu Y, He L, et al. TFEB-driven autophagy potentiates TGF-β induced migration in pancreatic cancer cells. J Exp Clin Cancer Res. 2019;38:340 pubmed 出版商

Yang M, Chen P, Liu J, Zhu S, Kroemer G, Klionsky D, et al. Clockophagy is a novel selective autophagy process favoring ferroptosis. Sci Adv. 2019;5:eaaw2238 pubmed 出版商

Dorsch L, Schuldt M, dos Remedios C, Schinkel A, de Jong P, Michels M, et al. Protein Quality Control Activation and Microtubule Remodeling in Hypertrophic Cardiomyopathy. Cells. 2019;8: pubmed 出版商

Grossmann D, Berenguer Escuder C, Bellet M, Scheibner D, Bohler J, Massart F, et al. Mutations in RHOT1 Disrupt Endoplasmic Reticulum-Mitochondria Contact Sites Interfering with Calcium Homeostasis and Mitochondrial Dynamics in Parkinson's Disease. Antioxid Redox Signal. 2019;31:1213-1234 pubmed 出版商

Ni Z, Kuang L, Chen H, Xie Y, Zhang B, Ouyang J, et al. The exosome-like vesicles from osteoarthritic chondrocyte enhanced mature IL-1β production of macrophages and aggravated synovitis in osteoarthritis. Cell Death Dis. 2019;10:522 pubmed 出版商

Jung S, Choe S, Woo H, Jeong H, An H, Moon H, et al. Autophagic death of neural stem cells mediates chronic stress-induced decline of adult hippocampal neurogenesis and cognitive deficits. Autophagy. 2019;:1-19 pubmed 出版商

Kumar V, Ayasolla K, Jha A, Mishra A, Vashistha H, Lan X, et al. Disrupted APOL1-miR193a Axis Dedifferentiates Podocytes through Autophagy Blockade in APOL1 Risk Milieu. Am J Physiol Cell Physiol. 2019;: pubmed 出版商

Xu D, Li X, Shao F, Lv G, Lv H, Lee J, et al. The protein kinase activity of fructokinase A specifies the antioxidant responses of tumor cells by phosphorylating p62. Sci Adv. 2019;5:eaav4570 pubmed 出版商

Zheng J, Croteau D, Bohr V, Akbari M. Diminished OPA1 expression and impaired mitochondrial morphology and homeostasis in Aprataxin-deficient cells. Nucleic Acids Res. 2019;: pubmed 出版商

Saito T, Kuma A, Sugiura Y, Ichimura Y, Obata M, Kitamura H, et al. Autophagy regulates lipid metabolism through selective turnover of NCoR1. Nat Commun. 2019;10:1567 pubmed 出版商

Li L, Kang H, Zhang Q, D Agati V, Al Awqati Q, Lin F. FoxO3 activation in hypoxic tubules prevents chronic kidney disease. J Clin Invest. 2019;129:2374-2389 pubmed 出版商

Li Z, Tian Y, Qu L, Mao J, Zhong H. AAV-Mig-6 Increase the Efficacy of TAE in VX2 Rabbit Model, Is Associated With JNK Mediated Autophagy. J Cancer. 2019;10:1060-1069 pubmed 出版商

Park H, Chung K, An H, Gim J, Hong J, Woo H, et al. Parkin Promotes Mitophagic Cell Death in Adult Hippocampal Neural Stem Cells Following Insulin Withdrawal. Front Mol Neurosci. 2019;12:46 pubmed 出版商

Carballo Carbajal I, Laguna A, Romero Gimenez J, Cuadros T, Bove J, Martinez Vicente M, et al. Brain tyrosinase overexpression implicates age-dependent neuromelanin production in Parkinson's disease pathogenesis. Nat Commun. 2019;10:973 pubmed 出版商

Hass D, Barnstable C. Mitochondrial Uncoupling Protein 2 Knock-out Promotes Mitophagy to Decrease Retinal Ganglion Cell Death in a Mouse Model of Glaucoma. J Neurosci. 2019;39:3582-3596 pubmed 出版商

Huang X, Gan G, Wang X, Xu T, Xie W. The HGF-MET axis coordinates liver cancer metabolism and autophagy for chemotherapeutic resistance. Autophagy. 2019;15:1258-1279 pubmed 出版商

Yambire K, Fernández Mosquera L, Steinfeld R, Mühle C, Ikonen E, Milosevic I, et al. Mitochondrial biogenesis is transcriptionally repressed in lysosomal lipid storage diseases. elife. 2019;8: pubmed 出版商

Zhang J, He J, Johnson J, Rahman F, Gavathiotis E, Cuervo A, et al. Chaperone-Mediated Autophagy Upregulation Rescues Megalin Expression and Localization in Cystinotic Proximal Tubule Cells. Front Endocrinol (Lausanne). 2019;10:21 pubmed 出版商

Zhang Y, Jiang Q, Xie S, Wu X, Zhou J, Sun H. Lead Induced Ototoxicity and Neurotoxicity in Adult Guinea Pig. Biomed Res Int. 2019;2019:3626032 pubmed 出版商

Dong X, Yang Y, Zhou Y, Bi X, Zhao N, Zhang Z, et al. Glutathione S-transferases P1 protects breast cancer cell from adriamycin-induced cell death through promoting autophagy. Cell Death Differ. 2019;: pubmed 出版商

Nassour J, Radford R, Correia A, Fusté J, Schoell B, Jauch A, et al. Autophagic cell death restricts chromosomal instability during replicative crisis. Nature. 2019;565:659-663 pubmed 出版商

Wang D, Xu Q, Yuan Q, Jia M, Niu H, Liu X, et al. Proteasome inhibition boosts autophagic degradation of ubiquitinated-AGR2 and enhances the antitumor efficiency of bevacizumab. Oncogene. 2019;38:3458-3474 pubmed 出版商

Chao H, Lin C, Zuo Q, Liu Y, Xiao M, Xu X, et al. Cardiolipin-Dependent Mitophagy Guides Outcome after Traumatic Brain Injury. J Neurosci. 2019;39:1930-1943 pubmed 出版商

Cui Y, Carosi J, Yang Z, Ariotti N, Kerr M, Parton R, et al. Retromer has a selective function in cargo sorting via endosome transport carriers. J Cell Biol. 2019;218:615-631 pubmed 出版商

Nitta A, Hori K, Tanida I, Igarashi A, Deyama Y, Ueno T, et al. Blocking LC3 lipidation and ATG12 conjugation reactions by ATG7 mutant protein containing C572S. Biochem Biophys Res Commun. 2019;508:521-526 pubmed 出版商

Cheruiyot A, Li S, Nickless A, Roth R, Fitzpatrick J, You Z. Compound C inhibits nonsense-mediated RNA decay independently of AMPK. PLoS ONE. 2018;13:e0204978 pubmed 出版商

Huang X, Wang X, Yuan X, Wu W, Lobie P, Wu Z. XIAP facilitates breast and colon carcinoma growth via promotion of p62 depletion through ubiquitination-dependent proteasomal degradation. Oncogene. 2019;38:1448-1460 pubmed 出版商

Gallot Y, Bohnert K, Straughn A, Xiong G, Hindi S, Kumar A. PERK regulates skeletal muscle mass and contractile function in adult mice. FASEB J. 2019;33:1946-1962 pubmed 出版商

Song K, Kim J, Lee Y, Bae H, Lee H, Woo S, et al. Mitochondrial reprogramming via ATP5H loss promotes multimodal cancer therapy resistance. J Clin Invest. 2018;128:4098-4114 pubmed 出版商

Pajares M, Rojo A, Arias E, Díaz Carretero A, Cuervo A, Cuadrado A. Transcription factor NFE2L2/NRF2 modulates chaperone-mediated autophagy through the regulation of LAMP2A. Autophagy. 2018;14:1310-1322 pubmed 出版商

Wang W, Xia Z, Farre J, Subramani S. TRIM37 deficiency induces autophagy through deregulating the MTORC1-TFEB axis. Autophagy. 2018;14:1574-1585 pubmed 出版商

Rapino F, Delaunay S, Rambow F, Zhou Z, Tharun L, de Tullio P, et al. Codon-specific translation reprogramming promotes resistance to targeted therapy. Nature. 2018;558:605-609 pubmed 出版商

Li F, Li Y, Liang H, Xu T, Kong Y, Huang M, et al. HECTD3 mediates TRAF3 polyubiquitination and type I interferon induction during bacterial infection. J Clin Invest. 2018;128:4148-4162 pubmed 出版商

Chhipa R, Fan Q, Anderson J, Muraleedharan R, Huang Y, Ciraolo G, et al. AMP kinase promotes glioblastoma bioenergetics and tumour growth. Nat Cell Biol. 2018;20:823-835 pubmed 出版商

Yang M, Li C, Zhu S, Cao L, Kroemer G, Zeh H, et al. TFAM is a novel mediator of immunogenic cancer cell death. Oncoimmunology. 2018;7:e1431086 pubmed 出版商

Perot B, Boussier J, Yatim N, Rossman J, Ingersoll M, Albert M. Autophagy diminishes the early interferon-? response to influenza A virus resulting in differential expression of interferon-stimulated genes. Cell Death Dis. 2018;9:539 pubmed 出版商

Leeman D, Hebestreit K, Ruetz T, Webb A, McKay A, Pollina E, et al. Lysosome activation clears aggregates and enhances quiescent neural stem cell activation during aging. Science. 2018;359:1277-1283 pubmed 出版商

Marrone L, Bus C, Schöndorf D, Fitzgerald J, Kübler M, Schmid B, et al. Generation of iPSCs carrying a common LRRK2 risk allele for in vitro modeling of idiopathic Parkinson's disease. PLoS ONE. 2018;13:e0192497 pubmed 出版商

Hsu C, Lee E, Gordon K, Paz E, Shen W, Ohnishi K, et al. MAP4K3 mediates amino acid-dependent regulation of autophagy via phosphorylation of TFEB. Nat Commun. 2018;9:942 pubmed 出版商

Agod Z, Pazmandi K, Bencze D, Vereb G, Biro T, Szabo A, et al. Signaling Lymphocyte Activation Molecule Family 5 Enhances Autophagy and Fine-Tunes Cytokine Response in Monocyte-Derived Dendritic Cells via Stabilization of Interferon Regulatory Factor 8. Front Immunol. 2018;9:62 pubmed 出版商

Goiran T, Duplan E, Rouland L, El Manaa W, Lauritzen I, Dunys J, et al. Nuclear p53-mediated repression of autophagy involves PINK1 transcriptional down-regulation. Cell Death Differ. 2018;25:873-884 pubmed 出版商

Shroff A, Sequeira R, Patel V, Reddy K. Knockout of autophagy gene, ATG5 in mice vaginal cells abrogates cytokine response and pathogen clearance during vaginal infection of Candida albicans. Cell Immunol. 2018;324:59-73 pubmed 出版商

Smith M, Harley M, Kemp A, Wills J, Lee M, Arends M, et al. CCPG1 Is a Non-canonical Autophagy Cargo Receptor Essential for ER-Phagy and Pancreatic ER Proteostasis. Dev Cell. 2018;44:217-232.e11 pubmed 出版商

Lee S, Bazick H, Chittoor Vinod V, Al Salihi M, Xia G, Notterpek L. Elevated Peripheral Myelin Protein 22, Reduced Mitotic Potential, and Proteasome Impairment in Dermal Fibroblasts from Charcot-Marie-Tooth Disease Type 1A Patients. Am J Pathol. 2018;188:728-738 pubmed 出版商

Sun H, Krauss R, Chang J, Teng B. PCSK9 deficiency reduces atherosclerosis, apolipoprotein B secretion, and endothelial dysfunction. J Lipid Res. 2018;59:207-223 pubmed 出版商

Ni Z, HE J, Wu Y, Hu C, Dai X, Yan X, et al. AKT-mediated phosphorylation of ATG4B impairs mitochondrial activity and enhances the Warburg effect in hepatocellular carcinoma cells. Autophagy. 2018;14:685-701 pubmed 出版商

Jimenez Orgaz A, Kvainickas A, Nägele H, Denner J, Eimer S, Dengjel J, et al. Control of RAB7 activity and localization through the retromer-TBC1D5 complex enables RAB7-dependent mitophagy. EMBO J. 2018;37:235-254 pubmed 出版商

Bansal M, Moharir S, Sailasree S, Sirohi K, Sudhakar C, Sarathi D, et al. Optineurin promotes autophagosome formation by recruiting the autophagy-related Atg12-5-16L1 complex to phagophores containing the Wipi2 protein. J Biol Chem. 2018;293:132-147 pubmed 出版商

Lüningschrör P, Binotti B, Dombert B, Heimann P, Pérez Lara A, Slotta C, et al. Plekhg5-regulated autophagy of synaptic vesicles reveals a pathogenic mechanism in motoneuron disease. Nat Commun. 2017;8:678 pubmed 出版商

Xu Y, Wang Y, Yao A, Xu Z, Dou H, Shen S, et al. Low Frequency Magnetic Fields Induce Autophagy-associated Cell Death in Lung Cancer through miR-486-mediated Inhibition of Akt/mTOR Signaling Pathway. Sci Rep. 2017;7:11776 pubmed 出版商

Ruan H, Ma Y, Torres S, Zhang B, Feriod C, Heck R, et al. Calcium-dependent O-GlcNAc signaling drives liver autophagy in adaptation to starvation. Genes Dev. 2017;31:1655-1665 pubmed 出版商

Bartolomeo R, Cinque L, De Leonibus C, Forrester A, Salzano A, Monfregola J, et al. mTORC1 hyperactivation arrests bone growth in lysosomal storage disorders by suppressing autophagy. J Clin Invest. 2017;127:3717-3729 pubmed 出版商

Tseng J, Xie L, Song S, Xie Y, Allen L, Ajit D, et al. The Deacetylase HDAC6 Mediates Endogenous Neuritic Tau Pathology. Cell Rep. 2017;20:2169-2183 pubmed 出版商

Rocchi A, Yamamoto S, Ting T, Fan Y, SADLEIR K, Wang Y, et al. A Becn1 mutation mediates hyperactive autophagic sequestration of amyloid oligomers and improved cognition in Alzheimer's disease. PLoS Genet. 2017;13:e1006962 pubmed 出版商

Button R, Roberts S, Willis T, Hanemann C, Luo S. Accumulation of autophagosomes confers cytotoxicity. J Biol Chem. 2017;292:13599-13614 pubmed 出版商

Dai S, Dulcey A, Hu X, Wassif C, Porter F, Austin C, et al. Methyl-β-cyclodextrin restores impaired autophagy flux in Niemann-Pick C1-deficient cells through activation of AMPK. Autophagy. 2017;13:1435-1451 pubmed 出版商

Tan Y, Ci Y, Dai X, Wu F, Guo J, Liu D, et al. Cullin 3SPOP ubiquitin E3 ligase promotes the poly-ubiquitination and degradation of HDAC6. Oncotarget. 2017;8:47890-47901 pubmed 出版商

Tan S, Chadha S, Liu Y, Gabasova E, Perera D, Ahmed K, et al. A Class of Environmental and Endogenous Toxins Induces BRCA2 Haploinsufficiency and Genome Instability. Cell. 2017;169:1105-1118.e15 pubmed 出版商

Wang G, Zhou H, Strulovici Barel Y, Al Hijji M, Ou X, Salit J, et al. Role of OSGIN1 in mediating smoking-induced autophagy in the human airway epithelium. Autophagy. 2017;13:1205-1220 pubmed 出版商

Sakamaki J, Wilkinson S, Hahn M, Tasdemir N, O Prey J, Clark W, et al. Bromodomain Protein BRD4 Is a Transcriptional Repressor of Autophagy and Lysosomal Function. Mol Cell. 2017;66:517-532.e9 pubmed 出版商

Nayar U, Sadek J, Reichel J, Hernandez Hopkins D, Akar G, Barelli P, et al. Identification of a nucleoside analog active against adenosine kinase-expressing plasma cell malignancies. J Clin Invest. 2017;127:2066-2080 pubmed 出版商

Wu D, Adamopoulos I. Loss of WDFY3 ameliorates severity of serum transfer-induced arthritis independently of autophagy. Cell Immunol. 2017;316:61-69 pubmed 出版商

Ashkenazi A, Bento C, Ricketts T, Vicinanza M, Siddiqi F, Pavel M, et al. Polyglutamine tracts regulate beclin 1-dependent autophagy. Nature. 2017;545:108-111 pubmed 出版商

Banerjee B, Koner D, Lal P, Saha N. Unique mitochondrial localization of arginase 1 and 2 in hepatocytes of air-breathing walking catfish, Clarias batrachus and their differential expression patterns under hyper-ammonia stress. Gene. 2017;622:13-22 pubmed 出版商

Kaufman D, Papillon J, Larose L, Iwawaki T, Cybulsky A. Deletion of inositol-requiring enzyme-1? in podocytes disrupts glomerular capillary integrity and autophagy. Mol Biol Cell. 2017;28:1636-1651 pubmed 出版商

Xiao Z, Gaertner S, Morresi Hauf A, Genzel R, Duell T, Ullrich A, et al. Metformin Triggers Autophagy to Attenuate Drug-Induced Apoptosis in NSCLC Cells, with Minor Effects on Tumors of Diabetic Patients. Neoplasia. 2017;19:385-395 pubmed 出版商

Gao Y, Zhuang Z, Gao S, Li X, Zhang Z, Ye Z, et al. Tetrahydrocurcumin reduces oxidative stress-induced apoptosis via the mitochondrial apoptotic pathway by modulating autophagy in rats after traumatic brain injury. Am J Transl Res. 2017;9:887-899 pubmed

Zhang Y, Nguyen D, Olzomer E, Poon G, Cole N, Puvanendran A, et al. Rescue of Pink1 Deficiency by Stress-Dependent Activation of Autophagy. Cell Chem Biol. 2017;24:471-480.e4 pubmed 出版商

Zhang X, Fan J, Wang S, Li Y, Wang Y, Li S, et al. Targeting CD47 and Autophagy Elicited Enhanced Antitumor Effects in Non-Small Cell Lung Cancer. Cancer Immunol Res. 2017;5:363-375 pubmed 出版商

Xu Q, Zhu N, Chen S, Zhao P, Ren H, Zhu S, et al. E3 Ubiquitin Ligase Nedd4 Promotes Japanese Encephalitis Virus Replication by Suppressing Autophagy in Human Neuroblastoma Cells. Sci Rep. 2017;7:45375 pubmed 出版商

Kang H, Park J, Choi K, Kim Y, Choi H, Jung C, et al. Chemical screening identifies ATM as a target for alleviating senescence. Nat Chem Biol. 2017;13:616-623 pubmed 出版商

Marwaha R, Arya S, Jagga D, Kaur H, Tuli A, Sharma M. The Rab7 effector PLEKHM1 binds Arl8b to promote cargo traffic to lysosomes. J Cell Biol. 2017;216:1051-1070 pubmed 出版商

Fajardo V, Gamu D, Mitchell A, Bloemberg D, Bombardier E, Chambers P, et al. Sarcolipin deletion exacerbates soleus muscle atrophy and weakness in phospholamban overexpressing mice. PLoS ONE. 2017;12:e0173708 pubmed 出版商

Kim J, Hyun H, Min S, Kang T. Sustained HSP25 Expression Induces Clasmatodendrosis via ER Stress in the Rat Hippocampus. Front Cell Neurosci. 2017;11:47 pubmed 出版商

Samuel S, Ghosh S, Majeed Y, Arunachalam G, Emara M, Ding H, et al. Metformin represses glucose starvation induced autophagic response in microvascular endothelial cells and promotes cell death. Biochem Pharmacol. 2017;132:118-132 pubmed 出版商

Møller A, Kampmann U, Hedegaard J, Thorsen K, Nordentoft I, Vendelbo M, et al. Altered gene expression and repressed markers of autophagy in skeletal muscle of insulin resistant patients with type 2 diabetes. Sci Rep. 2017;7:43775 pubmed 出版商

Datta S, Choudhury D, Das A, Das Mukherjee D, Das N, Roy S, et al. Paclitaxel resistance development is associated with biphasic changes in reactive oxygen species, mitochondrial membrane potential and autophagy with elevated energy production capacity in lung cancer cells: A chronological study. Tumour Biol. 2017;39:1010428317694314 pubmed 出版商

Kemter E, Frohlich T, Arnold G, Wolf E, Wanke R. Mitochondrial Dysregulation Secondary to Endoplasmic Reticulum Stress in Autosomal Dominant Tubulointerstitial Kidney Disease - UMOD (ADTKD-UMOD). Sci Rep. 2017;7:42970 pubmed 出版商

Kovacs T, Billes V, Komlos M, Hotzi B, Manzéger A, Tarnóci A, et al. The small molecule AUTEN-99 (autophagy enhancer-99) prevents the progression of neurodegenerative symptoms. Sci Rep. 2017;7:42014 pubmed 出版商

Wolfson R, Chantranupong L, Wyant G, Gu X, Orozco J, Shen K, et al. KICSTOR recruits GATOR1 to the lysosome and is necessary for nutrients to regulate mTORC1. Nature. 2017;543:438-442 pubmed 出版商

Delaney J, Patel C, Willis K, Haghighiabyaneh M, Axelrod J, Tancioni I, et al. Haploinsufficiency networks identify targetable patterns of allelic deficiency in low mutation ovarian cancer. Nat Commun. 2017;8:14423 pubmed 出版商

Jung J, Nayak A, Schaeffer V, Starzetz T, Kirsch A, Muller S, et al. Multiplex image-based autophagy RNAi screening identifies SMCR8 as ULK1 kinase activity and gene expression regulator. elife. 2017;6: pubmed 出版商

Chen S, Jing Y, Kang X, Yang L, Wang D, Zhang W, et al. Histone H2B monoubiquitination is a critical epigenetic switch for the regulation of autophagy. Nucleic Acids Res. 2017;45:1144-1158 pubmed 出版商

Roy D, Mondal S, Khurana A, Jung D, Hoffmann R, He X, et al. Loss of HSulf-1: The Missing Link between Autophagy and Lipid Droplets in Ovarian Cancer. Sci Rep. 2017;7:41977 pubmed 出版商

Russo V, Inglese C, Avallone L, Roperto F, Abate C, Zizzo N, et al. Sigma 2 receptor expression levels in blood and bladder from healthy and bladder cancer cattle. Vet Comp Oncol. 2017;15:1503-1512 pubmed 出版商

Kim M, Deng H, Wong Y, Siddique T, Krainc D. The Parkinson's disease-linked protein TMEM230 is required for Rab8a-mediated secretory vesicle trafficking and retromer trafficking. Hum Mol Genet. 2017;26:729-741 pubmed 出版商

Ma K, Fu W, Tang M, Zhang C, Hou T, Li R, et al. PTK2-mediated degradation of ATG3 impedes cancer cells susceptible to DNA damage treatment. Autophagy. 2017;13:579-591 pubmed 出版商

Ruf S, Heberle A, Langelaar Makkinje M, Gelino S, Wilkinson D, Gerbeth C, et al. PLK1 (polo like kinase 1) inhibits MTOR complex 1 and promotes autophagy. Autophagy. 2017;13:486-505 pubmed 出版商

Coccia M, Rossi A, Riccio A, Trotta E, Santoro M. Human NF-κB repressing factor acts as a stress-regulated switch for ribosomal RNA processing and nucleolar homeostasis surveillance. Proc Natl Acad Sci U S A. 2017;114:1045-1050 pubmed 出版商

Granato M, Rizzello C, Gilardini Montani M, Cuomo L, Vitillo M, Santarelli R, et al. Quercetin induces apoptosis and autophagy in primary effusion lymphoma cells by inhibiting PI3K/AKT/mTOR and STAT3 signaling pathways. J Nutr Biochem. 2017;41:124-136 pubmed 出版商

Borgia D, Malena A, Spinazzi M, Desbats M, Salviati L, Russell A, et al. Increased mitophagy in the skeletal muscle of spinal and bulbar muscular atrophy patients. Hum Mol Genet. 2017;26:1087-1103 pubmed 出版商

Sun A, Wei J, Childress C, Shaw J, Peng K, Shao G, et al. The E3 ubiquitin ligase NEDD4 is an LC3-interactive protein and regulates autophagy. Autophagy. 2017;13:522-537 pubmed 出版商

Pietrocola F, Demont Y, Castoldi F, Enot D, Durand S, Semeraro M, et al. Metabolic effects of fasting on human and mouse blood in vivo. Autophagy. 2017;13:567-578 pubmed 出版商

Capizzi M, Strappazzon F, Cianfanelli V, Papaleo E, Cecconi F. MIR7-3HG, a MYC-dependent modulator of cell proliferation, inhibits autophagy by a regulatory loop involving AMBRA1. Autophagy. 2017;13:554-566 pubmed 出版商

Laporte A, Barrott J, Yao R, Poulin N, Brodin B, Jones K, et al. HDAC and Proteasome Inhibitors Synergize to Activate Pro-Apoptotic Factors in Synovial Sarcoma. PLoS ONE. 2017;12:e0169407 pubmed 出版商

Hosoya M, Fujioka M, Sone T, Okamoto S, Akamatsu W, Ukai H, et al. Cochlear Cell Modeling Using Disease-Specific iPSCs Unveils a Degenerative Phenotype and Suggests Treatments for Congenital Progressive Hearing Loss. Cell Rep. 2017;18:68-81 pubmed 出版商

Wei Y, Chiang W, Sumpter R, Mishra P, Levine B. Prohibitin 2 Is an Inner Mitochondrial Membrane Mitophagy Receptor. Cell. 2017;168:224-238.e10 pubmed 出版商

Yeung P, Lai A, Son H, Zhang X, Hwang O, Chung S, et al. Aldose reductase deficiency leads to oxidative stress-induced dopaminergic neuronal loss and autophagic abnormality in an animal model of Parkinson's disease. Neurobiol Aging. 2017;50:119-133 pubmed 出版商

Da Ros M, Lehtiniemi T, Olotu O, Fischer D, Zhang F, Vihinen H, et al. FYCO1 and autophagy control the integrity of the haploid male germ cell-specific RNP granules. Autophagy. 2017;13:302-321 pubmed 出版商

Shi B, Huang Q, Birkett R, Doyle R, Dorfleutner A, Stehlik C, et al. SNAPIN is critical for lysosomal acidification and autophagosome maturation in macrophages. Autophagy. 2017;13:285-301 pubmed 出版商

Pavel M, Imarisio S, Menzies F, Jimenez Sanchez M, Siddiqi F, Wu X, et al. CCT complex restricts neuropathogenic protein aggregation via autophagy. Nat Commun. 2016;7:13821 pubmed 出版商

Su F, Myers V, Knezevic T, Wang J, Gao E, Madesh M, et al. Bcl-2-associated athanogene 3 protects the heart from ischemia/reperfusion injury. JCI Insight. 2016;1:e90931 pubmed 出版商

Li J, Chen T, Xiao M, Li N, Wang S, Su H, et al. Mouse Sirt3 promotes autophagy in AngII-induced myocardial hypertrophy through the deacetylation of FoxO1. Oncotarget. 2016;7:86648-86659 pubmed 出版商

Cramer S, Saha A, Liu J, Tadi S, Tiziani S, Yan W, et al. Systemic depletion of L-cyst(e)ine with cyst(e)inase increases reactive oxygen species and suppresses tumor growth. Nat Med. 2017;23:120-127 pubmed 出版商

Tábara L, Escalante R. VMP1 Establishes ER-Microdomains that Regulate Membrane Contact Sites and Autophagy. PLoS ONE. 2016;11:e0166499 pubmed 出版商

Sakata K, Araki K, Nakano H, Nishina T, Komazawa Sakon S, Murai S, et al. Novel method to rescue a lethal phenotype through integration of target gene onto the X-chromosome. Sci Rep. 2016;6:37200 pubmed 出版商

Cao L, Riascos Bernal D, Chinnasamy P, Dunaway C, Hou R, Pujato M, et al. Control of mitochondrial function and cell growth by the atypical cadherin Fat1. Nature. 2016;539:575-578 pubmed 出版商

Lee M, Sumpter R, Zou Z, Sirasanagandla S, Wei Y, Mishra P, et al. Peroxisomal protein PEX13 functions in selective autophagy. EMBO Rep. 2017;18:48-60 pubmed 出版商

Li D, Xie B, Wu X, Li J, Ding Y, Wen X, et al. Late-stage inhibition of autophagy enhances calreticulin surface exposure. Oncotarget. 2016;7:80842-80854 pubmed 出版商

Cai Y, Yang L, Hu G, Chen X, Niu F, Yuan L, et al. Regulation of morphine-induced synaptic alterations: Role of oxidative stress, ER stress, and autophagy. J Cell Biol. 2016;215:245-258 pubmed

Lim J, Kim H, Nguyen K, Cho K. The role of TLR9 in stress-dependent autophagy formation. Biochem Biophys Res Commun. 2016;481:219-226 pubmed 出版商

Fan Y, Wang N, Rocchi A, Zhang W, Vassar R, Zhou Y, et al. Identification of natural products with neuronal and metabolic benefits through autophagy induction. Autophagy. 2017;13:41-56 pubmed 出版商

Han J, Bae J, Choi C, Choi S, Kang H, Jo E, et al. Autophagy induced by AXL receptor tyrosine kinase alleviates acute liver injury via inhibition of NLRP3 inflammasome activation in mice. Autophagy. 2016;12:2326-2343 pubmed

Liu L, Tao Z, Zheng L, Brooke J, Smith C, Liu D, et al. FoxO1 interacts with transcription factor EB and differentially regulates mitochondrial uncoupling proteins via autophagy in adipocytes. Cell Death Discov. 2016;2:16066 pubmed

Yang M, Wang B, Miao L, Xu X, He X. Autophagy is involved in aldosterone‑induced mesangial cell proliferation. Mol Med Rep. 2016;14:4638-4642 pubmed 出版商

Wang H, Chen S, Lo W. Identification of Cofilin-1 Induces G0/G1 Arrest and Autophagy in Angiotensin-(1-7)-treated Human Aortic Endothelial Cells from iTRAQ Quantitative Proteomics. Sci Rep. 2016;6:35372 pubmed 出版商

Figueroa González G, García Castillo V, Coronel Hernández J, López Urrutia E, León Cabrera S, Arias Romero L, et al. Anti-inflammatory and Antitumor Activity of a Triple Therapy for a Colitis-Related Colorectal Cancer. J Cancer. 2016;7:1632-1644 pubmed

Vodicka P, Chase K, Iuliano M, Tousley A, Valentine D, Sapp E, et al. Autophagy Activation by Transcription Factor EB (TFEB) in Striatum of HDQ175/Q7 Mice. J Huntingtons Dis. 2016;5:249-260 pubmed

White S, McDermott M, Sufit R, Kosmac K, Bugg A, Gonzalez Freire M, et al. Walking performance is positively correlated to calf muscle fiber size in peripheral artery disease subjects, but fibers show aberrant mitophagy: an observational study. J Transl Med. 2016;14:284 pubmed 出版商

Wei R, Lin S, Wu W, Chen L, Li C, Chen H, et al. A microtubule inhibitor, ABT-751, induces autophagy and delays apoptosis in Huh-7 cells. Toxicol Appl Pharmacol. 2016;311:88-98 pubmed 出版商

Mercado Pimentel M, Igarashi S, Dunn A, Behbahani M, Miller C, Read C, et al. The Novel Small Molecule Inhibitor, OSU-T315, Suppresses Vestibular Schwannoma and Meningioma Growth by Inhibiting PDK2 Function in the AKT Pathway Activation. Austin J Med Oncol. 2016;3: pubmed

Hubert V, Peschel A, Langer B, Groger M, Rees A, Kain R. LAMP-2 is required for incorporating syntaxin-17 into autophagosomes and for their fusion with lysosomes. Biol Open. 2016;5:1516-1529 pubmed 出版商

Teo W, Kerr M, Teasdale R. MTMR4 Is Required for the Stability of the Salmonella-Containing Vacuole. Front Cell Infect Microbiol. 2016;6:91 pubmed 出版商

Qin Y, Liu Y, Hao W, Decker Y, Tomic I, Menger M, et al. Stimulation of TLR4 Attenuates Alzheimer's Disease-Related Symptoms and Pathology in Tau-Transgenic Mice. J Immunol. 2016;197:3281-3292 pubmed

Heulot M, Chevalier N, Puyal J, Margue C, Michel S, Kreis S, et al. The TAT-RasGAP317-326 anti-cancer peptide can kill in a caspase-, apoptosis-, and necroptosis-independent manner. Oncotarget. 2016;7:64342-64359 pubmed 出版商

Cudré Cung H, Zavadakova P, Do Vale Pereira S, Remacle N, Henry H, Ivanisevic J, et al. Ammonium accumulation is a primary effect of 2-methylcitrate exposure in an in vitro model for brain damage in methylmalonic aciduria. Mol Genet Metab. 2016;119:57-67 pubmed 出版商

Conlon D, Thomas T, Fedotova T, Hernandez Ono A, Di Paolo G, Chan R, et al. Inhibition of apolipoprotein B synthesis stimulates endoplasmic reticulum autophagy that prevents steatosis. J Clin Invest. 2016;126:3852-3867 pubmed 出版商

Mirkheshti N, Park S, Jiang S, Cropper J, Werner S, Song C, et al. Dual targeting of androgen receptor and mTORC1 by salinomycin in prostate cancer. Oncotarget. 2016;7:62240-62254 pubmed 出版商

Lin M, Liu H, Xiong Q, Niu H, Cheng Z, Yamamoto A, et al. Ehrlichia secretes Etf-1 to induce autophagy and capture nutrients for its growth through RAB5 and class III phosphatidylinositol 3-kinase. Autophagy. 2016;12:2145-2166 pubmed

Ratovitski E. Tumor Protein (TP)-p53 Members as Regulators of Autophagy in Tumor Cells upon Marine Drug Exposure. Mar Drugs. 2016;14: pubmed 出版商

Weikel K, Cacicedo J, Ruderman N, Ido Y. Knockdown of GSK3β increases basal autophagy and AMPK signalling in nutrient-laden human aortic endothelial cells. Biosci Rep. 2016;36: pubmed 出版商

Jo Y, Park N, Park S, Kim B, Shin J, Jo D, et al. O-GlcNAcylation of ATG4B positively regulates autophagy by increasing its hydroxylase activity. Oncotarget. 2016;7:57186-57196 pubmed 出版商

Ogasawara R, Fujita S, Hornberger T, Kitaoka Y, Makanae Y, Nakazato K, et al. The role of mTOR signalling in the regulation of skeletal muscle mass in a rodent model of resistance exercise. Sci Rep. 2016;6:31142 pubmed 出版商

Xu S, Law B, Mok S, Leung E, Fan X, Coghi P, et al. Autophagic degradation of epidermal growth factor receptor in gefitinib-resistant lung cancer by celastrol. Int J Oncol. 2016;49:1576-88 pubmed 出版商

Xing Y, Cao R, Hu H. TLR and NLRP3 inflammasome-dependent innate immune responses to tumor-derived autophagosomes (DRibbles). Cell Death Dis. 2016;7:e2322 pubmed 出版商

Bartlett J, Trivedi P, Yeung P, Kienesberger P, Pulinilkunnil T. Doxorubicin impairs cardiomyocyte viability by suppressing transcription factor EB expression and disrupting autophagy. Biochem J. 2016;473:3769-3789 pubmed

Wang J, Zhou J, Kho D, Reiners J, Wu G. Role for DUSP1 (dual-specificity protein phosphatase 1) in the regulation of autophagy. Autophagy. 2016;12:1791-1803 pubmed

Grinshtein N, Rioseco C, Marcellus R, UEHLING D, Aman A, Lun X, et al. Small molecule epigenetic screen identifies novel EZH2 and HDAC inhibitors that target glioblastoma brain tumor-initiating cells. Oncotarget. 2016;7:59360-59376 pubmed 出版商

Buckingham E, Jarosinski K, Jackson W, Carpenter J, Grose C. Exocytosis of Varicella-Zoster Virus Virions Involves a Convergence of Endosomal and Autophagy Pathways. J Virol. 2016;90:8673-85 pubmed 出版商

Geng J, Li J, Huang T, Zhao K, Chen Q, Guo W, et al. A novel manganese complex selectively induces malignant glioma cell death by targeting mitochondria. Mol Med Rep. 2016;14:1970-8 pubmed 出版商

Pajares M, Jiménez Moreno N, García Yagüe A, Escoll M, De Ceballos M, Van Leuven F, et al. Transcription factor NFE2L2/NRF2 is a regulator of macroautophagy genes. Autophagy. 2016;12:1902-1916 pubmed

Hewitt G, Carroll B, Sarallah R, Correia Melo C, Ogrodnik M, Nelson G, et al. SQSTM1/p62 mediates crosstalk between autophagy and the UPS in DNA repair. Autophagy. 2016;12:1917-1930 pubmed

Zea A, Stewart T, Ascani J, Tate D, Finkel Jimenez B, Wilk A, et al. Activation of the IL-2 Receptor in Podocytes: A Potential Mechanism for Podocyte Injury in Idiopathic Nephrotic Syndrome?. PLoS ONE. 2016;11:e0157907 pubmed 出版商

Pan H, Zhong X, Lee S. Sustained activation of mTORC1 in macrophages increases AMPKα-dependent autophagy to maintain cellular homeostasis. BMC Biochem. 2016;17:14 pubmed 出版商

Bramini M, Sacchetti S, Armirotti A, Rocchi A, Vazquez E, León Castellanos V, et al. Graphene Oxide Nanosheets Disrupt Lipid Composition, Ca(2+) Homeostasis, and Synaptic Transmission in Primary Cortical Neurons. ACS Nano. 2016;10:7154-71 pubmed 出版商

Dejesus R, Moretti F, McAllister G, Wang Z, Bergman P, Liu S, et al. Functional CRISPR screening identifies the ufmylation pathway as a regulator of SQSTM1/p62. elife. 2016;5: pubmed 出版商

Davis M, Delaney J, Patel C, Storgard R, Stupack D. Nelfinavir is effective against human cervical cancer cells in vivo: a potential treatment modality in resource-limited settings. Drug Des Devel Ther. 2016;10:1837-46 pubmed 出版商

Hamlin A, Basford J, Jaeschke A, Hui D. LRP1 Protein Deficiency Exacerbates Palmitate-induced Steatosis and Toxicity in Hepatocytes. J Biol Chem. 2016;291:16610-9 pubmed 出版商

Shin H, Kim H, Oh S, Lee J, Kee M, Ko H, et al. AMPK-SKP2-CARM1 signalling cascade in transcriptional regulation of autophagy. Nature. 2016;534:553-7 pubmed 出版商

Gómez Sánchez R, Yakhine Diop S, Bravo San Pedro J, Pizarro Estrella E, Rodríguez Arribas M, Climent V, et al. PINK1 deficiency enhances autophagy and mitophagy induction. Mol Cell Oncol. 2016;3:e1046579 pubmed 出版商

Kuramoto K, Wang N, Fan Y, Zhang W, Schoenen F, Frankowski K, et al. Autophagy activation by novel inducers prevents BECN2-mediated drug tolerance to cannabinoids. Autophagy. 2016;12:1460-71 pubmed 出版商

Andersson A, Andersson B, Lorell C, Raffetseder J, Larsson M, Blomgran R. Autophagy induction targeting mTORC1 enhances Mycobacterium tuberculosis replication in HIV co-infected human macrophages. Sci Rep. 2016;6:28171 pubmed 出版商

Wijdeven R, Janssen H, Nahidiazar L, Janssen L, Jalink K, Berlin I, et al. Cholesterol and ORP1L-mediated ER contact sites control autophagosome transport and fusion with the endocytic pathway. Nat Commun. 2016;7:11808 pubmed 出版商

Kobayashi K, Araya J, Minagawa S, Hara H, Saito N, Kadota T, et al. Involvement of PARK2-Mediated Mitophagy in Idiopathic Pulmonary Fibrosis Pathogenesis. J Immunol. 2016;197:504-16 pubmed 出版商

Ando K, Tomimura K, Sazdovitch V, Suain V, Yilmaz Z, Authelet M, et al. Level of PICALM, a key component of clathrin-mediated endocytosis, is correlated with levels of phosphotau and autophagy-related proteins and is associated with tau inclusions in AD, PSP and Pick disease. Neurobiol Dis. 2016;94:32-43 pubmed 出版商

Foltz S, Luan J, Call J, Patel A, Peissig K, Fortunato M, et al. Four-week rapamycin treatment improves muscular dystrophy in a fukutin-deficient mouse model of dystroglycanopathy. Skelet Muscle. 2016;6:20 pubmed 出版商

Adams O, Dislich B, Berezowska S, Schläfli A, Seiler C, Kröll D, et al. Prognostic relevance of autophagy markers LC3B and p62 in esophageal adenocarcinomas. Oncotarget. 2016;7:39241-39255 pubmed 出版商

Barnard R, Regan D, Hansen R, Maycotte P, Thorburn A, Gustafson D. Autophagy Inhibition Delays Early but Not Late-Stage Metastatic Disease. J Pharmacol Exp Ther. 2016;358:282-93 pubmed 出版商

Elimam H, Papillon J, Kaufman D, Guillemette J, Aoudjit L, Gross R, et al. Genetic Ablation of Calcium-independent Phospholipase A2? Induces Glomerular Injury in Mice. J Biol Chem. 2016;291:14468-82 pubmed 出版商

Droubi A, Bulley S, Clarke J, Irvine R. Nuclear localizations of phosphatidylinositol 5-phosphate 4-kinases ? and ? are dynamic and independently regulated during starvation-induced stress. Biochem J. 2016;473:2155-63 pubmed 出版商

Ranjan A, Srivastava S. Penfluridol suppresses pancreatic tumor growth by autophagy-mediated apoptosis. Sci Rep. 2016;6:26165 pubmed 出版商

Koskela A, Reinisalo M, Petrovski G, Sinha D, Olmiere C, Karjalainen R, et al. Nutraceutical with Resveratrol and Omega-3 Fatty Acids Induces Autophagy in ARPE-19 Cells. Nutrients. 2016;8: pubmed 出版商

Liu L, Wang C, Lin Y, Xi Y, Li H, Shi S, et al. Suppression of calcium?sensing receptor ameliorates cardiac hypertrophy through inhibition of autophagy. Mol Med Rep. 2016;14:111-20 pubmed 出版商

Park S, Yi H, Suh N, Park Y, Koh J, Jeong S, et al. Inhibition of EHMT2/G9a epigenetically increases the transcription of Beclin-1 via an increase in ROS and activation of NF-?B. Oncotarget. 2016;7:39796-39808 pubmed 出版商

Song J, Sun Y, Peluso I, Zeng Y, Yu X, Lu J, et al. A novel curcumin analog binds to and activates TFEB in vitro and in vivo independent of MTOR inhibition. Autophagy. 2016;12:1372-89 pubmed 出版商

Pastore N, Brady O, Diab H, Martina J, Sun L, Huynh T, et al. TFEB and TFE3 cooperate in the regulation of the innate immune response in activated macrophages. Autophagy. 2016;12:1240-58 pubmed 出版商

Karvela M, Baquero P, Kuntz E, Mukhopadhyay A, Mitchell R, Allan E, et al. ATG7 regulates energy metabolism, differentiation and survival of Philadelphia-chromosome-positive cells. Autophagy. 2016;12:936-48 pubmed 出版商

Ting W, Yang J, Kuo C, Xiao Z, Lu X, Yeh Y, et al. Environmental tobacco smoke increases autophagic effects but decreases longevity associated with Sirt-1 protein expression in young C57BL mice hearts. Oncotarget. 2016;7:39017-39025 pubmed 出版商

De Filippis L, Halikere A, McGowan H, Moore J, Tischfield J, Hart R, et al. Ethanol-mediated activation of the NLRP3 inflammasome in iPS cells and iPS cells-derived neural progenitor cells. Mol Brain. 2016;9:51 pubmed 出版商

Onesto E, Colombrita C, Gumina V, Borghi M, Dusi S, Doretti A, et al. Gene-specific mitochondria dysfunctions in human TARDBP and C9ORF72 fibroblasts. Acta Neuropathol Commun. 2016;4:47 pubmed 出版商

Xu J, Li J, Wang J, Chi Y, Zhang K, Cui R. Heme oxygenase?1 protects H2O2?insulted glomerular mesangial cells from excessive autophagy. Mol Med Rep. 2016;13:5269-75 pubmed 出版商

Swiader A, Nahapetyan H, Faccini J, D Angelo R, Mucher E, Elbaz M, et al. Mitophagy acts as a safeguard mechanism against human vascular smooth muscle cell apoptosis induced by atherogenic lipids. Oncotarget. 2016;7:28821-35 pubmed 出版商

Follo C, Barbone D, Richards W, Bueno R, Broaddus V. Autophagy initiation correlates with the autophagic flux in 3D models of mesothelioma and with patient outcome. Autophagy. 2016;12:1180-94 pubmed 出版商

Pryde K, Smith H, Chau K, Schapira A. PINK1 disables the anti-fission machinery to segregate damaged mitochondria for mitophagy. J Cell Biol. 2016;213:163-71 pubmed 出版商

Lai C, Tsai C, Kuo W, Ho T, Day C, Pai P, et al. Multi-Strain Probiotics Inhibit Cardiac Myopathies and Autophagy to Prevent Heart Injury in High-Fat Diet-Fed Rats. Int J Med Sci. 2016;13:277-85 pubmed 出版商

Wang Q, Xue L, Zhang X, Bu S, Zhu X, Lai D. Autophagy protects ovarian cancer-associated fibroblasts against oxidative stress. Cell Cycle. 2016;15:1376-85 pubmed 出版商

Xiao L, Shi X, Zhang Y, Zhu Y, Zhu L, Tian W, et al. YAP induces cisplatin resistance through activation of autophagy in human ovarian carcinoma cells. Onco Targets Ther. 2016;9:1105-14 pubmed 出版商

Wohlgemuth S, Ramirez Lee Y, Tao S, Monteiro A, Ahmed B, Dahl G. Short communication: Effect of heat stress on markers of autophagy in the mammary gland during the dry period. J Dairy Sci. 2016;99:4875-4880 pubmed 出版商

Ren J, Li J, Liu X, Feng Y, Gui Y, Yang J, et al. Quercetin Inhibits Fibroblast Activation and Kidney Fibrosis Involving the Suppression of Mammalian Target of Rapamycin and β-catenin Signaling. Sci Rep. 2016;6:23968 pubmed 出版商

Dey A, Mustafi S, Saha S, Kumar Dhar Dwivedi S, Mukherjee P, Bhattacharya R. Inhibition of BMI1 induces autophagy-mediated necroptosis. Autophagy. 2016;12:659-70 pubmed 出版商

Park J, Jung C, Seo M, Otto N, Grunwald D, Kim K, et al. The ULK1 complex mediates MTORC1 signaling to the autophagy initiation machinery via binding and phosphorylating ATG14. Autophagy. 2016;12:547-64 pubmed 出版商

Phelps Polirer K, Abt M, Smith D, Yeh E. Co-Targeting of JNK and HUNK in Resistant HER2-Positive Breast Cancer. PLoS ONE. 2016;11:e0153025 pubmed 出版商

Lin T, Chang Y, Lee S, Campbell M, Wang T, Shen S, et al. REST reduction is essential for hypoxia-induced neuroendocrine differentiation of prostate cancer cells by activating autophagy signaling. Oncotarget. 2016;7:26137-51 pubmed 出版商

Krishnan V, White Z, McMahon C, Hodgetts S, Fitzgerald M, Shavlakadze T, et al. A Neurogenic Perspective of Sarcopenia: Time Course Study of Sciatic Nerves From Aging Mice. J Neuropathol Exp Neurol. 2016;75:464-78 pubmed 出版商

Prieto J, León M, Ponsoda X, Sendra R, Bort R, Ferrer Lorente R, et al. Early ERK1/2 activation promotes DRP1-dependent mitochondrial fission necessary for cell reprogramming. Nat Commun. 2016;7:11124 pubmed 出版商

Xia X, Che Y, Gao Y, Zhao S, Ao C, Yang H, et al. Arginine Supplementation Recovered the IFN-?-Mediated Decrease in Milk Protein and Fat Synthesis by Inhibiting the GCN2/eIF2? Pathway, Which Induces Autophagy in Primary Bovine Mammary Epithelial Cells. Mol Cells. 2016;39:410-7 pubmed 出版商

Chen S, Wang C, Yeo S, Liang C, Okamoto T, Sun S, et al. Distinct roles of autophagy-dependent and -independent functions of FIP200 revealed by generation and analysis of a mutant knock-in mouse model. Genes Dev. 2016;30:856-69 pubmed 出版商

Gschweitl M, Ulbricht A, Barnes C, Enchev R, Stoffel Studer I, Meyer Schaller N, et al. A SPOPL/Cullin-3 ubiquitin ligase complex regulates endocytic trafficking by targeting EPS15 at endosomes. elife. 2016;5:e13841 pubmed 出版商

Lopes V, Loitto V, Audinot J, Bayat N, Gutleb A, Cristobal S. Dose-dependent autophagic effect of titanium dioxide nanoparticles in human HaCaT cells at non-cytotoxic levels. J Nanobiotechnology. 2016;14:22 pubmed 出版商

Ruparelia A, Oorschot V, Ramm G, Bryson Richardson R. FLNC myofibrillar myopathy results from impaired autophagy and protein insufficiency. Hum Mol Genet. 2016;25:2131-2142 pubmed

Yeo S, Itahana Y, Guo A, Han R, Iwamoto K, Nguyen H, et al. Transglutaminase 2 contributes to a TP53-induced autophagy program to prevent oncogenic transformation. elife. 2016;5:e07101 pubmed 出版商

Jennewein L, Ronellenfitsch M, Antonietti P, Ilina E, Jung J, Stadel D, et al. Diagnostic and clinical relevance of the autophago-lysosomal network in human gliomas. Oncotarget. 2016;7:20016-32 pubmed 出版商

Scotton C, Bovolenta M, Schwartz E, Falzarano M, Martoni E, Passarelli C, et al. Deep RNA profiling identified CLOCK and molecular clock genes as pathophysiological signatures in collagen VI myopathy. J Cell Sci. 2016;129:1671-84 pubmed 出版商

Yu L, Wu W, Gu C, Zhong D, Zhao X, Kong Y, et al. Obatoclax impairs lysosomal function to block autophagy in cisplatin-sensitive and -resistant esophageal cancer cells. Oncotarget. 2016;7:14693-707 pubmed 出版商

Li M, Lu G, Hu J, Shen X, Ju J, Gao Y, et al. EVA1A/TMEM166 Regulates Embryonic Neurogenesis by Autophagy. Stem Cell Reports. 2016;6:396-410 pubmed 出版商

Cao L, Qin X, Peterson M, Haller S, Wilson K, Hu N, et al. CARD9 knockout ameliorates myocardial dysfunction associated with high fat diet-induced obesity. J Mol Cell Cardiol. 2016;92:185-95 pubmed 出版商

Zhang W, Shi H, Zhang M, Liu B, Mao S, Li L, et al. Poly C binding protein 1 represses autophagy through downregulation of LC3B to promote tumor cell apoptosis in starvation. Int J Biochem Cell Biol. 2016;73:127-136 pubmed 出版商

Lei Y, Kansy B, Li J, Cong L, Liu Y, Trivedi S, et al. EGFR-targeted mAb therapy modulates autophagy in head and neck squamous cell carcinoma through NLRX1-TUFM protein complex. Oncogene. 2016;35:4698-707 pubmed 出版商

Kim N, Kim M, Sung P, Bae Y, Shin E, Yoo J. Interferon-inducible protein SCOTIN interferes with HCV replication through the autolysosomal degradation of NS5A. Nat Commun. 2016;7:10631 pubmed 出版商

Liu Y, Takahashi Y, Desai N, Zhang J, Serfass J, Shi Y, et al. Bif-1 deficiency impairs lipid homeostasis and causes obesity accompanied by insulin resistance. Sci Rep. 2016;6:20453 pubmed 出版商

Wu X, Fleming A, Ricketts T, Pavel M, Virgin H, Menzies F, et al. Autophagy regulates Notch degradation and modulates stem cell development and neurogenesis. Nat Commun. 2016;7:10533 pubmed 出版商

Gentry E, Henderson B, Arrant A, Gearing M, Feng Y, Riddle N, et al. Rho Kinase Inhibition as a Therapeutic for Progressive Supranuclear Palsy and Corticobasal Degeneration. J Neurosci. 2016;36:1316-23 pubmed 出版商

Button R, Vincent J, Strang C, Luo S. Dual PI-3 kinase/mTOR inhibition impairs autophagy flux and induces cell death independent of apoptosis and necroptosis. Oncotarget. 2016;7:5157-75 pubmed 出版商

Kim M, Sandford E, Gatica D, Qiu Y, Liu X, Zheng Y, et al. Mutation in ATG5 reduces autophagy and leads to ataxia with developmental delay. elife. 2016;5: pubmed 出版商

Goulielmaki M, Koustas E, Moysidou E, Vlassi M, Sasazuki T, Shirasawa S, et al. BRAF associated autophagy exploitation: BRAF and autophagy inhibitors synergise to efficiently overcome resistance of BRAF mutant colorectal cancer cells. Oncotarget. 2016;7:9188-221 pubmed 出版商

Ruiz A, Rockfield S, Taran N, Haller E, Engelman R, Flores I, et al. Effect of hydroxychloroquine and characterization of autophagy in a mouse model of endometriosis. Cell Death Dis. 2016;7:e2059 pubmed 出版商

Zhou Q, Yen A, Rymarczyk G, Asai H, Trengrove C, Aziz N, et al. Impairment of PARK14-dependent Ca(2+) signalling is a novel determinant of Parkinson's disease. Nat Commun. 2016;7:10332 pubmed 出版商

Mukherjee R, Chakrabarti O. Ubiquitin-mediated regulation of the E3 ligase GP78 by MGRN1 in trans affects mitochondrial homeostasis. J Cell Sci. 2016;129:757-73 pubmed 出版商

Wu B, Yu L, Wang Y, Wang H, Li C, Yin Y, et al. Aldehyde dehydrogenase 2 activation in aged heart improves the autophagy by reducing the carbonyl modification on SIRT1. Oncotarget. 2016;7:2175-88 pubmed 出版商

Kraft L, Manral P, Dowler J, Kenworthy A. Nuclear LC3 Associates with Slowly Diffusing Complexes that Survey the Nucleolus. Traffic. 2016;17:369-99 pubmed 出版商

Xie C, Ginet V, Sun Y, Koike M, Zhou K, Li T, et al. Neuroprotection by selective neuronal deletion of Atg7 in neonatal brain injury. Autophagy. 2016;12:410-23 pubmed 出版商

Wang Y, Xu S, Xu W, Yang H, Hu P, Li Y. Sodium formate induces autophagy and apoptosis via the JNK signaling pathway of photoreceptor cells. Mol Med Rep. 2016;13:1111-8 pubmed 出版商

Chen Y, Tsou B, Hu S, Ma H, Liu X, Yen Y, et al. Autophagy induction causes a synthetic lethal sensitization to ribonucleotide reductase inhibition in breast cancer cells. Oncotarget. 2016;7:1984-99 pubmed 出版商

Stotland A, Gottlieb R. α-MHC MitoTimer mouse: In vivo mitochondrial turnover model reveals remarkable mitochondrial heterogeneity in the heart. J Mol Cell Cardiol. 2016;90:53-8 pubmed 出版商

Schwab A, Ebert A. Neurite Aggregation and Calcium Dysfunction in iPSC-Derived Sensory Neurons with Parkinson's Disease-Related LRRK2 G2019S Mutation. Stem Cell Reports. 2015;5:1039-1052 pubmed 出版商

Martínez Zamora A, Meseguer S, Esteve J, Villarroya M, Aguado C, Enríquez J, et al. Defective Expression of the Mitochondrial-tRNA Modifying Enzyme GTPBP3 Triggers AMPK-Mediated Adaptive Responses Involving Complex I Assembly Factors, Uncoupling Protein 2, and the Mitochondrial Pyruvate Carrier. PLoS ONE. 2015;10:e0144273 pubmed 出版商

McIlroy G, Tammireddy S, Maskrey B, Grant L, Doherty M, Watson D, et al. Fenretinide mediated retinoic acid receptor signalling and inhibition of ceramide biosynthesis regulates adipogenesis, lipid accumulation, mitochondrial function and nutrient stress signalling in adipocytes and adipose tissue. Biochem Pharmacol. 2016;100:86-97 pubmed 出版商

Pettersen K, Monsen V, HakvÃ¥g Pettersen C, Overland H, Pettersen G, Samdal H, et al. DHA-induced stress response in human colon cancer cells - Focus on oxidative stress and autophagy. Free Radic Biol Med. 2016;90:158-72 pubmed 出版商

Huang Y, Chen Y, Lai Y, Cheng C, Lin T, Su Y, et al. Resveratrol alleviates the cytotoxicity induced by the radiocontrast agent, ioxitalamate, by reducing the production of reactive oxygen species in HK-2 human renal proximal tubule epithelial cells in vitro. Int J Mol Med. 2016;37:83-91 pubmed 出版商

Chrisam M, Pirozzi M, Castagnaro S, Blaauw B, Polishchuck R, Cecconi F, et al. Reactivation of autophagy by spermidine ameliorates the myopathic defects of collagen VI-null mice. Autophagy. 2015;11:2142-52 pubmed 出版商

Lesmana R, Sinha R, Singh B, Zhou J, Ohba K, Wu Y, et al. Thyroid Hormone Stimulation of Autophagy Is Essential for Mitochondrial Biogenesis and Activity in Skeletal Muscle. Endocrinology. 2016;157:23-38 pubmed 出版商

Alnasser H, Guan Q, Zhang F, Gleave M, Nguan C, Du C. Requirement of clusterin expression for prosurvival autophagy in hypoxic kidney tubular epithelial cells. Am J Physiol Renal Physiol. 2016;310:F160-73 pubmed 出版商

Majumder P, Chakrabarti O. Mahogunin regulates fusion between amphisomes/MVBs and lysosomes via ubiquitination of TSG101. Cell Death Dis. 2015;6:e1970 pubmed 出版商

Dou Z, Xu C, Donahue G, Shimi T, Pan J, Zhu J, et al. Autophagy mediates degradation of nuclear lamina. Nature. 2015;527:105-9 pubmed 出版商

Lin C, Chen Y, Lin C, Chen Y, Lo G, Lee P, et al. Amiodarone as an autophagy promoter reduces liver injury and enhances liver regeneration and survival in mice after partial hepatectomy. Sci Rep. 2015;5:15807 pubmed 出版商

Ivankovic D, Chau K, Schapira A, Gegg M. Mitochondrial and lysosomal biogenesis are activated following PINK1/parkin-mediated mitophagy. J Neurochem. 2016;136:388-402 pubmed 出版商

van Geldermalsen M, Wang Q, Nagarajah R, Marshall A, Thoeng A, Gao D, et al. ASCT2/SLC1A5 controls glutamine uptake and tumour growth in triple-negative basal-like breast cancer. Oncogene. 2016;35:3201-8 pubmed 出版商

Xiong R, Zhou W, Siegel D, Kitson R, Freed C, Moody C, et al. A Novel Hsp90 Inhibitor Activates Compensatory Heat Shock Protein Responses and Autophagy and Alleviates Mutant A53T α-Synuclein Toxicity. Mol Pharmacol. 2015;88:1045-54 pubmed 出版商

Sorrell S, Golder Z, Johnstone D, Frankl F. Renal peroxiredoxin 6 interacts with anion exchanger 1 and plays a novel role in pH homeostasis. Kidney Int. 2016;89:105-112 pubmed 出版商

Granato M, Santarelli R, Filardi M, Gonnella R, Farina A, Torrisi M, et al. The activation of KSHV lytic cycle blocks autophagy in PEL cells. Autophagy. 2015;11:1978-1986 pubmed 出版商

Koukourakis M, Kalamida D, Giatromanolaki A, Zois C, Sivridis E, Pouliliou S, et al. Autophagosome Proteins LC3A, LC3B and LC3C Have Distinct Subcellular Distribution Kinetics and Expression in Cancer Cell Lines. PLoS ONE. 2015;10:e0137675 pubmed 出版商

Pellegrini C, Columbaro M, Capanni C, D Apice M, Cavallo C, Murdocca M, et al. All-trans retinoic acid and rapamycin normalize Hutchinson Gilford progeria fibroblast phenotype. Oncotarget. 2015;6:29914-28 pubmed 出版商

Granato M, Gilardini Montani M, Filardi M, Faggioni A, Cirone M. Capsaicin triggers immunogenic PEL cell death, stimulates DCs and reverts PEL-induced immune suppression. Oncotarget. 2015;6:29543-54 pubmed 出版商

Moreau K, Ghislat G, Hochfeld W, Renna M, Zavodszky E, Runwal G, et al. Transcriptional regulation of Annexin A2 promotes starvation-induced autophagy. Nat Commun. 2015;6:8045 pubmed 出版商

Triplett J, Tramutola A, Swomley A, Kirk J, Grimes K, Lewis K, et al. Age-related changes in the proteostasis network in the brain of the naked mole-rat: Implications promoting healthy longevity. Biochim Biophys Acta. 2015;1852:2213-24 pubmed 出版商

Hermanova I, Arruabarrena Aristorena A, Valis K, Nůsková H, Alberich Jorda M, Fiser K, et al. Pharmacological inhibition of fatty-acid oxidation synergistically enhances the effect of l-asparaginase in childhood ALL cells. Leukemia. 2016;30:209-18 pubmed 出版商

Johansson I, Monsen V, Pettersen K, Mildenberger J, Misund K, Kaarniranta K, et al. The marine n-3 PUFA DHA evokes cytoprotection against oxidative stress and protein misfolding by inducing autophagy and NFE2L2 in human retinal pigment epithelial cells. Autophagy. 2015;11:1636-51 pubmed 出版商

Chesser A, Ganeshan V, Yang J, Johnson G. Epigallocatechin-3-gallate enhances clearance of phosphorylated tau in primary neurons. Nutr Neurosci. 2016;19:21-31 pubmed 出版商

Wu H, Jiang Z, Ding P, Shao L, Liu R. Hypoxia-induced autophagy mediates cisplatin resistance in lung cancer cells. Sci Rep. 2015;5:12291 pubmed 出版商

Perera R, Stoykova S, Nicolay B, Ross K, Fitamant J, Boukhali M, et al. Transcriptional control of autophagy-lysosome function drives pancreatic cancer metabolism. Nature. 2015;524:361-5 pubmed 出版商

Wang I, Sun K, Tsai T, Chen C, Chang S, Yu T, et al. MiR-20a-5p mediates hypoxia-induced autophagy by targeting ATG16L1 in ischemic kidney injury. Life Sci. 2015;136:133-41 pubmed 出版商

Yang S, Lin H, Chang V, Chen C, Liu Y, Wang J, et al. Lovastatin overcomes gefitinib resistance through TNF-α signaling in human cholangiocarcinomas with different LKB1 statuses in vitro and in vivo. Oncotarget. 2015;6:23857-73 pubmed

Su X, Yu Y, Zhong Y, Giannopoulou E, Hu X, Liu H, et al. Interferon-γ regulates cellular metabolism and mRNA translation to potentiate macrophage activation. Nat Immunol. 2015;16:838-849 pubmed 出版商

Metge B, Mitra A, Chen D, Shevde L, Samant R. N-Myc and STAT Interactor regulates autophagy and chemosensitivity in breast cancer cells. Sci Rep. 2015;5:11995 pubmed 出版商

Ohashi A, Ohori M, Iwai K, Nakayama Y, Nambu T, Morishita D, et al. Aneuploidy generates proteotoxic stress and DNA damage concurrently with p53-mediated post-mitotic apoptosis in SAC-impaired cells. Nat Commun. 2015;6:7668 pubmed 出版商

Wang J, Ma L, Tang X, Zhang X, Qiao Y, Shi Y, et al. Doxorubicin induces apoptosis by targeting Madcam1 and AKT and inhibiting protein translation initiation in hepatocellular carcinoma cells. Oncotarget. 2015;6:24075-91 pubmed

Campbell G, Rawat P, Bruckman R, Spector S. Human Immunodeficiency Virus Type 1 Nef Inhibits Autophagy through Transcription Factor EB Sequestration. PLoS Pathog. 2015;11:e1005018 pubmed 出版商

Giordano C, Lemaire C, Li T, Kimoff R, Petrof B. Autophagy-associated atrophy and metabolic remodeling of the mouse diaphragm after short-term intermittent hypoxia. PLoS ONE. 2015;10:e0131068 pubmed 出版商

Liu K, Frazier W. Phosphorylation of the BNIP3 C-Terminus Inhibits Mitochondrial Damage and Cell Death without Blocking Autophagy. PLoS ONE. 2015;10:e0129667 pubmed 出版商

Hu G, McQuiston T, Bernard A, Park Y, Qiu J, Vural A, et al. A conserved mechanism of TOR-dependent RCK-mediated mRNA degradation regulates autophagy. Nat Cell Biol. 2015;17:930-942 pubmed 出版商

Park S, Choi S, Yoo S, Nah J, Jeong E, Kim H, et al. Pyruvate stimulates mitophagy via PINK1 stabilization. Cell Signal. 2015;27:1824-30 pubmed 出版商

Yuan J, Zhang Y, Sheng Y, Fu X, Cheng H, Zhou R. MYBL2 guides autophagy suppressor VDAC2 in the developing ovary to inhibit autophagy through a complex of VDAC2-BECN1-BCL2L1 in mammals. Autophagy. 2015;11:1081-98 pubmed 出版商

Huang C, Lee C, Lin H, Chen M, Lin C, Chang J. Autophagy-Regulated ROS from Xanthine Oxidase Acts as an Early Effector for Triggering Late Mitochondria-Dependent Apoptosis in Cathepsin S-Targeted Tumor Cells. PLoS ONE. 2015;10:e0128045 pubmed 出版商

Sun T, Li X, Zhang P, Chen W, Zhang H, Li D, et al. Acetylation of Beclin 1 inhibits autophagosome maturation and promotes tumour growth. Nat Commun. 2015;6:7215 pubmed 出版商

Milkereit R, Persaud A, Vanoaica L, Guetg A, Verrey F, Rotin D. LAPTM4b recruits the LAT1-4F2hc Leu transporter to lysosomes and promotes mTORC1 activation. Nat Commun. 2015;6:7250 pubmed 出版商

Li J, Ren J, Liu X, Jiang L, He W, Yuan W, et al. Rictor/mTORC2 signaling mediates TGFβ1-induced fibroblast activation and kidney fibrosis. Kidney Int. 2015;88:515-27 pubmed 出版商

Del Mar N, von Buttlar X, Yu A, Guley N, Reiner A, Honig M. A novel closed-body model of spinal cord injury caused by high-pressure air blasts produces extensive axonal injury and motor impairments. Exp Neurol. 2015;271:53-71 pubmed 出版商

Cheng H, Liang Y, Kuo Y, Chuu C, Lin C, Lee M, et al. Identification of thioridazine, an antipsychotic drug, as an antiglioblastoma and anticancer stem cell agent using public gene expression data. Cell Death Dis. 2015;6:e1753 pubmed 出版商

Kim Y, Kang Y, Lee N, Kim K, Hwang Y, Kim H, et al. Uvrag targeting by Mir125a and Mir351 modulates autophagy associated with Ewsr1 deficiency. Autophagy. 2015;11:796-811 pubmed 出版商

Zhang L, Wang H, Ding K, Xu J. FTY720 induces autophagy-related apoptosis and necroptosis in human glioblastoma cells. Toxicol Lett. 2015;236:43-59 pubmed 出版商

Zhao J, Molitor T, Langston J, Nichols R. LRRK2 dephosphorylation increases its ubiquitination. Biochem J. 2015;469:107-20 pubmed 出版商

Laguna A, Schintu N, Nobre A, Alvarsson A, Volakakis N, Jacobsen J, et al. Dopaminergic control of autophagic-lysosomal function implicates Lmx1b in Parkinson's disease. Nat Neurosci. 2015;18:826-35 pubmed 出版商

Marsh N, Wareham A, White B, Miskiewicz E, Landry J, MacPhee D. HSPB8 and the Cochaperone BAG3 Are Highly Expressed During the Synthetic Phase of Rat Myometrium Programming During Pregnancy. Biol Reprod. 2015;92:131 pubmed 出版商

Meidhof S, Brabletz S, Lehmann W, Preca B, Mock K, Ruh M, et al. ZEB1-associated drug resistance in cancer cells is reversed by the class I HDAC inhibitor mocetinostat. EMBO Mol Med. 2015;7:831-47 pubmed 出版商

Kett L, Stiller B, Bernath M, Tasset I, Blesa J, Jackson Lewis V, et al. α-Synuclein-independent histopathological and motor deficits in mice lacking the endolysosomal Parkinsonism protein Atp13a2. J Neurosci. 2015;35:5724-42 pubmed 出版商

Akizu N, Cantagrel V, Zaki M, Al Gazali L, Wang X, Rosti R, et al. Biallelic mutations in SNX14 cause a syndromic form of cerebellar atrophy and lysosome-autophagosome dysfunction. Nat Genet. 2015;47:528-34 pubmed 出版商

Roost M, van Iperen L, De Melo Bernardo A, Mummery C, Carlotti F, de Koning E, et al. Lymphangiogenesis and angiogenesis during human fetal pancreas development. Vasc Cell. 2014;6:22 pubmed 出版商

Strohecker A, Joshi S, Possemato R, Abraham R, Sabatini D, White E. Identification of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase as a novel autophagy regulator by high content shRNA screening. Oncogene. 2015;34:5662-76 pubmed 出版商

Desantis A, Bruno T, Catena V, De Nicola F, Goeman F, Iezzi S, et al. Che-1-induced inhibition of mTOR pathway enables stress-induced autophagy. EMBO J. 2015;34:1214-30 pubmed 出版商

Wengrod J, Wang D, Weiss S, Zhong H, Osman I, Gardner L. Phosphorylation of eIF2α triggered by mTORC1 inhibition and PP6C activation is required for autophagy and is aberrant in PP6C-mutated melanoma. Sci Signal. 2015;8:ra27 pubmed 出版商

Yi Y, Kang H, Bae E, Oh S, Seong Y, Bae I. β-TrCP1 degradation is a novel action mechanism of PI3K/mTOR inhibitors in triple-negative breast cancer cells. Exp Mol Med. 2015;47:e143 pubmed 出版商

Medina D, Di Paola S, Peluso I, Armani A, De Stefani D, Venditti R, et al. Lysosomal calcium signalling regulates autophagy through calcineurin and ​TFEB. Nat Cell Biol. 2015;17:288-99 pubmed

Pedro J, Wei Y, Sica V, Maiuri M, Zou Z, Kroemer G, et al. BAX and BAK1 are dispensable for ABT-737-induced dissociation of the BCL2-BECN1 complex and autophagy. Autophagy. 2015;11:452-9 pubmed 出版商

Ulbricht A, Gehlert S, Leciejewski B, Schiffer T, Bloch W, Höhfeld J. Induction and adaptation of chaperone-assisted selective autophagy CASA in response to resistance exercise in human skeletal muscle. Autophagy. 2015;11:538-46 pubmed 出版商

Sanjurjo L, Amézaga N, Aran G, Naranjo Gómez M, Arias L, Armengol C, et al. The human CD5L/AIM-CD36 axis: A novel autophagy inducer in macrophages that modulates inflammatory responses. Autophagy. 2015;11:487-502 pubmed 出版商

Jabir M, Hopkins L, Ritchie N, Ullah I, Bayes H, Li D, et al. Mitochondrial damage contributes to Pseudomonas aeruginosa activation of the inflammasome and is downregulated by autophagy. Autophagy. 2015;11:166-82 pubmed 出版商

Polletta L, Vernucci E, Carnevale I, Arcangeli T, Rotili D, Palmerio S, et al. SIRT5 regulation of ammonia-induced autophagy and mitophagy. Autophagy. 2015;11:253-70 pubmed 出版商

Kim E, Shin J, Park S, Jo Y, Kim J, Kang I, et al. Inhibition of autophagy suppresses sertraline-mediated primary ciliogenesis in retinal pigment epithelium cells. PLoS ONE. 2015;10:e0118190 pubmed 出版商

Kommaddi R, Jean Charles P, Shenoy S. Phosphorylation of the deubiquitinase USP20 by protein kinase A regulates post-endocytic trafficking of β2 adrenergic receptors to autophagosomes during physiological stress. J Biol Chem. 2015;290:8888-903 pubmed 出版商

Greenall S, Donoghue J, van Sinderen M, Dubljevic V, Budiman S, Devlin M, et al. EGFRvIII-mediated transactivation of receptor tyrosine kinases in glioma: mechanism and therapeutic implications. Oncogene. 2015;34:5277-87 pubmed 出版商

Guerrero A, Iglesias C, Raguz S, Floridia E, Gil J, Pombo C, et al. The cerebral cavernous malformation 3 gene is necessary for senescence induction. Aging Cell. 2015;14:274-83 pubmed 出版商

Rohatgi R, Janusis J, Leonard D, Bellvé K, Fogarty K, Baehrecke E, et al. Beclin 1 regulates growth factor receptor signaling in breast cancer. Oncogene. 2015;34:5352-62 pubmed 出版商

Arel Dubeau A, Longpré F, Bournival J, Tremblay C, Demers Lamarche J, Haskova P, et al. Cucurbitacin E has neuroprotective properties and autophagic modulating activities on dopaminergic neurons. Oxid Med Cell Longev. 2014;2014:425496 pubmed 出版商

Liu S, Sarkar C, Dinizo M, Faden A, Koh E, Lipinski M, et al. Disrupted autophagy after spinal cord injury is associated with ER stress and neuronal cell death. Cell Death Dis. 2015;6:e1582 pubmed 出版商

Valianou M, Cox A, Pichette B, Hartley S, Paladhi U, Astrinidis A. Pharmacological inhibition of Polo-like kinase 1 (PLK1) by BI-2536 decreases the viability and survival of hamartin and tuberin deficient cells via induction of apoptosis and attenuation of autophagy. Cell Cycle. 2015;14:399-407 pubmed 出版商

Bueno M, Lai Y, Romero Y, Brands J, St Croix C, Kamga C, et al. PINK1 deficiency impairs mitochondrial homeostasis and promotes lung fibrosis. J Clin Invest. 2015;125:521-38 pubmed 出版商

Mudie S, Bandarra D, Batie M, Biddlestone J, Moniz S, Ortmann B, et al. PITX1, a specificity determinant in the HIF-1α-mediated transcriptional response to hypoxia. Cell Cycle. 2014;13:3878-91 pubmed 出版商

Sykora P, Misiak M, Wang Y, Ghosh S, Leandro G, Liu D, et al. DNA polymerase β deficiency leads to neurodegeneration and exacerbates Alzheimer disease phenotypes. Nucleic Acids Res. 2015;43:943-59 pubmed 出版商

Mir S, George N, Zahoor L, Harms R, Guinn Z, SARVETNICK N. Inhibition of autophagic turnover in β-cells by fatty acids and glucose leads to apoptotic cell death. J Biol Chem. 2015;290:6071-85 pubmed 出版商

Bifsha P, Yang J, Fisher R, Drouin J. Rgs6 is required for adult maintenance of dopaminergic neurons in the ventral substantia nigra. PLoS Genet. 2014;10:e1004863 pubmed 出版商

Chen G, Meng C, Lin K, Tuan H, Yang H, Chen C, et al. Graphene oxide as a chemosensitizer: diverted autophagic flux, enhanced nuclear import, elevated necrosis and improved antitumor effects. Biomaterials. 2015;40:12-22 pubmed 出版商

Varga M, Fodor E, Vellai T. Autophagy in zebrafish. Methods. 2015;75:172-80 pubmed 出版商

Kaushik G, Venugopal A, Ramamoorthy P, Standing D, Subramaniam D, Umar S, et al. Honokiol inhibits melanoma stem cells by targeting notch signaling. Mol Carcinog. 2015;54:1710-21 pubmed 出版商

Porter K, Hirt J, Stamer W, Liton P. Autophagic dysregulation in glaucomatous trabecular meshwork cells. Biochim Biophys Acta. 2015;1852:379-85 pubmed 出版商

Kim T, Kim H, Kang Y, Yoon S, Lee J, Choi W, et al. Psammaplin A induces Sirtuin 1-dependent autophagic cell death in doxorubicin-resistant MCF-7/adr human breast cancer cells and xenografts. Biochim Biophys Acta. 2015;1850:401-10 pubmed 出版商

Roe N, Xu X, Kandadi M, Hu N, Pang J, Weiser Evans M, et al. Targeted deletion of PTEN in cardiomyocytes renders cardiac contractile dysfunction through interruption of Pink1-AMPK signaling and autophagy. Biochim Biophys Acta. 2015;1852:290-8 pubmed 出版商

Nitta T, Sato Y, Ren X, Harada K, Sasaki M, Hirano S, et al. Autophagy may promote carcinoma cell invasion and correlate with poor prognosis in cholangiocarcinoma. Int J Clin Exp Pathol. 2014;7:4913-21 pubmed

Liu Y, Wan S, Zhang P, Zhang W, Zheng J, Lin J, et al. Expression levels of autophagy related proteins and their prognostic significance in retinocytoma and retinoblastoma. Int J Ophthalmol. 2014;7:594-601 pubmed 出版商

Li L, Wu P, Lee J, Li P, Hsieh W, Ho C, et al. Hinokitiol induces DNA damage and autophagy followed by cell cycle arrest and senescence in gefitinib-resistant lung adenocarcinoma cells. PLoS ONE. 2014;9:e104203 pubmed 出版商

Brown D, LASSEGUE B, Lee M, Zafari R, Long J, Saavedra H, et al. Poldip2 knockout results in perinatal lethality, reduced cellular growth and increased autophagy of mouse embryonic fibroblasts. PLoS ONE. 2014;9:e96657 pubmed 出版商

Mancias J, Wang X, Gygi S, Harper J, Kimmelman A. Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy. Nature. 2014;509:105-9 pubmed 出版商

Porter K, Jeyabalan N, Liton P. MTOR-independent induction of autophagy in trabecular meshwork cells subjected to biaxial stretch. Biochim Biophys Acta. 2014;1843:1054-62 pubmed 出版商

Li J, Xu Z, Jiang L, Mao J, Zeng Z, Fang L, et al. Rictor/mTORC2 protects against cisplatin-induced tubular cell death and acute kidney injury. Kidney Int. 2014;86:86-102 pubmed 出版商

Rubio N, Verrax J, Dewaele M, Verfaillie T, Johansen T, Piette J, et al. p38(MAPK)-regulated induction of p62 and NBR1 after photodynamic therapy promotes autophagic clearance of ubiquitin aggregates and reduces reactive oxygen species levels by supporting Nrf2-antioxidant signaling. Free Radic Biol Med. 2014;67:292-303 pubmed 出版商

Gurkar A, Chu K, Raj L, Bouley R, Lee S, Kim Y, et al. Identification of ROCK1 kinase as a critical regulator of Beclin1-mediated autophagy during metabolic stress. Nat Commun. 2013;4:2189 pubmed 出版商

Yuan Y, Tang A, Castoreno A, Kuo S, Wang Q, Kuballa P, et al. Gossypol and an HMT G9a inhibitor act in synergy to induce cell death in pancreatic cancer cells. Cell Death Dis. 2013;4:e690 pubmed 出版商

Willis M, Min J, Wang S, McDonough H, Lockyer P, Wadosky K, et al. Carboxyl terminus of Hsp70-interacting protein (CHIP) is required to modulate cardiac hypertrophy and attenuate autophagy during exercise. Cell Biochem Funct. 2013;31:724-35 pubmed 出版商

Newman A, Scholefield C, Kemp A, Newman M, McIver E, Kamal A, et al. TBK1 kinase addiction in lung cancer cells is mediated via autophagy of Tax1bp1/Ndp52 and non-canonical NF-κB signalling. PLoS ONE. 2012;7:e50672 pubmed 出版商