Moore T, Cheng L, Wolf D, Ngo J, Segawa M, Zhu X, et al. Parkin regulates adiposity by coordinating mitophagy with mitochondrial biogenesis in white adipocytes. Nat Commun. 2022;13:6661 pubmed 出版商

Tong J, Li D, Meng H, Sun D, Lan X, Ni M, et al. Targeting a novel inducible GPX4 alternative isoform to alleviate ferroptosis and treat metabolic-associated fatty liver disease. Acta Pharm Sin B. 2022;12:3650-3666 pubmed 出版商

Chen T, Shi Z, Zhao Y, Meng X, Zhao S, Zheng L, et al. LncRNA Airn maintains LSEC differentiation to alleviate liver fibrosis via the KLF2-eNOS-sGC pathway. BMC Med. 2022;20:335 pubmed 出版商

Abousaad S, Ahmed F, Abouzeid A, Ongeri E. Meprin β expression modulates the interleukin-6 mediated JAK2-STAT3 signaling pathway in ischemia/reperfusion-induced kidney injury. Physiol Rep. 2022;10:e15468 pubmed 出版商

Wang F, Li M, Zhang A, Li H, Jiang C, Guo J. PCSK9 Modulates Macrophage Polarization-Mediated Ventricular Remodeling after Myocardial Infarction. J Immunol Res. 2022;2022:7685796 pubmed 出版商

Zhang L, Zheng D, Yan Y, Yu Y, Chen R, Li Z, et al. Myeloid cell-specific deletion of Capns1 prevents macrophage polarization toward the M1 phenotype and reduces interstitial lung disease in the bleomycin model of systemic sclerosis. Arthritis Res Ther. 2022;24:148 pubmed 出版商

Chou P, Luo C, Wali N, Lin W, Ng S, Wang C, et al. A chemical probe inhibitor targeting STAT1 restricts cancer stem cell traits and angiogenesis in colorectal cancer. J Biomed Sci. 2022;29:20 pubmed 出版商

Xu J, Li Z, Tower R, Negri S, Wang Y, Meyers C, et al. NGF-p75 signaling coordinates skeletal cell migration during bone repair. Sci Adv. 2022;8:eabl5716 pubmed 出版商

Chen B, Li R, Kubota A, Alex L, Frangogiannis N. Identification of macrophages in normal and injured mouse tissues using reporter lines and antibodies. Sci Rep. 2022;12:4542 pubmed 出版商

Wang Q, Chen Y, Xie Y, Yang D, Sun Y, Yuan Y, et al. Histone H1.2 promotes hepatocarcinogenesis by regulating signal transducer and activator of transcription 3 signaling. Cancer Sci. 2022;113:1679-1692 pubmed 出版商

Ye Q, Chen H, Ma H, Xiang X, Hu S, Xia C, et al. Xiaoyu Xiezhuo Drink Protects against Ischemia-Reperfusion Acute Kidney Injury in Aged Mice through Inhibiting the TGF-β1/Smad3 and HIF1 Signaling Pathways. Biomed Res Int. 2021;2021:9963732 pubmed 出版商

Zhang P, Schlecht A, Wolf J, Boneva S, Laich Y, Koch J, et al. The role of interferon regulatory factor 8 for retinal tissue homeostasis and development of choroidal neovascularisation. J Neuroinflammation. 2021;18:215 pubmed 出版商

Guo W, Liu J, Cheng L, Liu Z, Zheng X, Liang H, et al. Metformin Alleviates Steatohepatitis in Diet-Induced Obese Mice in a SIRT1-Dependent Way. Front Pharmacol. 2021;12:704112 pubmed 出版商

Zhao J, Chen J, Li Y, Xia L, Wu Y. Bruton's tyrosine kinase regulates macrophage‑induced inflammation in the diabetic kidney via NLRP3 inflammasome activation. Int J Mol Med. 2021;48: pubmed 出版商

Abbate J, Macri F, Arfuso F, Iaria C, Capparucci F, Anfuso C, et al. Anti-Atherogenic Effect of 10% Supplementation of Anchovy (Engraulis encrasicolus) Waste Protein Hydrolysates in ApoE-Deficient Mice. Nutrients. 2021;13: pubmed 出版商

Choi E, Jeong J, Jang H, Ahn Y, Kim K, An H, et al. Skeletal Lipocalin-2 Is Associated with Iron-Related Oxidative Stress in ob/ob Mice with Sarcopenia. Antioxidants (Basel). 2021;10: pubmed 出版商

Li L, Yang L, Yang F, Zhao X, Xue S, Gong F. Ginkgo biloba Extract 50 (GBE50) Ameliorates Insulin Resistance, Hepatic Steatosis and Liver Injury in High Fat Diet-Fed Mice. J Inflamm Res. 2021;14:1959-1971 pubmed 出版商

Tan S, Liu X, Chen L, Wu X, Tao L, Pan X, et al. Fas/FasL mediates NF-κBp65/PUMA-modulated hepatocytes apoptosis via autophagy to drive liver fibrosis. Cell Death Dis. 2021;12:474 pubmed 出版商

Maier A, Reichhart N, Gonnermann J, Kociok N, Riechardt A, Gundlach E, et al. Effects of TNFα receptor TNF-Rp55- or TNF-Rp75- deficiency on corneal neovascularization and lymphangiogenesis in the mouse. PLoS ONE. 2021;16:e0245143 pubmed 出版商

Cheah F, Presicce P, Tan T, Carey B, Kallapur S. Studying the Effects of Granulocyte-Macrophage Colony-Stimulating Factor on Fetal Lung Macrophages During the Perinatal Period Using the Mouse Model. Front Pediatr. 2021;9:614209 pubmed 出版商

Zhou M, Wang X, Shi Y, Ding Y, Li X, Xie T, et al. Deficiency of ITGAM Attenuates Experimental Abdominal Aortic Aneurysm in Mice. J Am Heart Assoc. 2021;10:e019900 pubmed 出版商

Reyes J, Ekmark Lewén S, Perdiki M, Klingstedt T, Hoffmann A, Wiechec E, et al. Accumulation of alpha-synuclein within the liver, potential role in the clearance of brain pathology associated with Parkinson's disease. Acta Neuropathol Commun. 2021;9:46 pubmed 出版商

Li J, Zhang H, Dong Y, Wang X, Wang G. Omega-3FAs Can Inhibit the Inflammation and Insulin Resistance of Adipose Tissue Caused by HHcy Induced Lipids Profile Changing in Mice. Front Physiol. 2021;12:628122 pubmed 出版商

Wang X, Zhao Y, Zhou D, Tian Y, Feng G, Lu Z. Gab2 deficiency suppresses high-fat diet-induced obesity by reducing adipose tissue inflammation and increasing brown adipose function in mice. Cell Death Dis. 2021;12:212 pubmed 出版商

Khatib Shahidi R, M Hoffmann J, Hedjazifar S, Bonnet L, K Baboota R, Heasman S, et al. Adult mice are unresponsive to AAV8-Gremlin1 gene therapy targeting the liver. PLoS ONE. 2021;16:e0247300 pubmed 出版商

Chen L, Wu H, Ren C, Liu G, Zhang W, Liu W, et al. Inhibition of PDGF-BB reduces alkali-induced corneal neovascularization in mice. Mol Med Rep. 2021;23:1 pubmed 出版商

Hidalgo Sastre A, Kuebelsbeck L, Jochheim L, Staufer L, Altmayr F, Johannes W, et al. Toll-like receptor 3 expression in myeloid cells is essential for efficient regeneration after acute pancreatitis in mice. Eur J Immunol. 2021;51:1182-1194 pubmed 出版商

Sharma N, Hans C. Interleukin 12p40 Deficiency Promotes Abdominal Aortic Aneurysm by Activating CCN2/MMP2 Pathways. J Am Heart Assoc. 2021;10:e017633 pubmed 出版商

Abbate J, Macri F, Capparucci F, Iaria C, Briguglio G, Cicero L, et al. Administration of Protein Hydrolysates from Anchovy (Engraulis Encrasicolus) Waste for Twelve Weeks Decreases Metabolic Dysfunction-Associated Fatty Liver Disease Severity in ApoE-/-Mice. Animals (Basel). 2020;10: pubmed 出版商

Kalinski A, Yoon C, Huffman L, Duncker P, Kohen R, Passino R, et al. Analysis of the immune response to sciatic nerve injury identifies efferocytosis as a key mechanism of nerve debridement. elife. 2020;9: pubmed 出版商

Yifan Z, Benxiang N, Zheng X, Luwei X, Liuhua Z, Yuzheng G, et al. Ceftriaxone Calcium Crystals Induce Acute Kidney Injury by NLRP3-Mediated Inflammation and Oxidative Stress Injury. Oxid Med Cell Longev. 2020;2020:6428498 pubmed 出版商

Tashita C, Hoshi M, Hirata A, Nakamoto K, Ando T, Hattori T, et al. Kynurenine plays an immunosuppressive role in 2,4,6-trinitrobenzene sulfate-induced colitis in mice. World J Gastroenterol. 2020;26:918-932 pubmed 出版商

von Roemeling C, Wang Y, Qie Y, Yuan H, Zhao H, Liu X, et al. Therapeutic modulation of phagocytosis in glioblastoma can activate both innate and adaptive antitumour immunity. Nat Commun. 2020;11:1508 pubmed 出版商

Xu M, Ge C, Qin Y, Lou D, Li Q, Feng J, et al. Functional loss of inactive rhomboid-like protein 2 mitigates obesity by suppressing pro-inflammatory macrophage activation-triggered adipose inflammation. Mol Metab. 2020;34:112-123 pubmed 出版商

Li W, Zhang X, Wu F, Zhou Y, Bao Z, Li H, et al. Gastric cancer-derived mesenchymal stromal cells trigger M2 macrophage polarization that promotes metastasis and EMT in gastric cancer. Cell Death Dis. 2019;10:918 pubmed 出版商

Xu M, Xu H, Lin Y, Sun X, Wang L, Fang Z, et al. LECT2, a Ligand for Tie1, Plays a Crucial Role in Liver Fibrogenesis. Cell. 2019;178:1478-1492.e20 pubmed 出版商

Jung M, Wells D, Rusch J, Ahmad S, Marchini J, Myers S, et al. Unified single-cell analysis of testis gene regulation and pathology in five mouse strains. elife. 2019;8: pubmed 出版商

Sivaram N, McLaughlin P, Han H, Petrenko O, Jiang Y, Ballou L, et al. Tumor-intrinsic PIK3CA represses tumor immunogenecity in a model of pancreatic cancer. J Clin Invest. 2019;130: pubmed 出版商

Liu M, Yin L, Li W, Hu J, Wang H, Ye B, et al. C1q/TNF-related protein-9 promotes macrophage polarization and improves cardiac dysfunction after myocardial infarction. J Cell Physiol. 2019;234:18731-18747 pubmed 出版商

Zhu W, Zhao Z, Chou F, Zuo L, Liu T, Yeh S, et al. Loss of the androgen receptor suppresses intrarenal calcium oxalate crystals deposition via altering macrophage recruitment/M2 polarization with change of the miR-185-5p/CSF-1 signals. Cell Death Dis. 2019;10:275 pubmed 出版商

Georgouli M, Herraiz C, Crosas Molist E, Fanshawe B, Maiques O, Perdrix A, et al. Regional Activation of Myosin II in Cancer Cells Drives Tumor Progression via a Secretory Cross-Talk with the Immune Microenvironment. Cell. 2019;176:757-774.e23 pubmed 出版商

Chute C, Yang X, Meyer K, Yang N, O Neil K, Kasza I, et al. Syndecan-1 induction in lung microenvironment supports the establishment of breast tumor metastases. Breast Cancer Res. 2018;20:66 pubmed 出版商

Qing X, Chinenov Y, Redecha P, Madaio M, Roelofs J, FARBER G, et al. iRhom2 promotes lupus nephritis through TNF-? and EGFR signaling. J Clin Invest. 2018;128:1397-1412 pubmed 出版商

Gao Z, Daquinag A, Su F, Snyder B, Kolonin M. PDGFRα/PDGFRβ signaling balance modulates progenitor cell differentiation into white and beige adipocytes. Development. 2018;145: pubmed 出版商

Nagashima H, Shinoda M, Honda K, Kamio N, Watanabe M, Suzuki T, et al. CXCR4 signaling in macrophages contributes to periodontal mechanical hypersensitivity in Porphyromonas gingivalis-induced periodontitis in mice. Mol Pain. 2017;13:1744806916689269 pubmed 出版商

Zhang H, Yue Y, Sun T, Wu X, Xiong S. Transmissible endoplasmic reticulum stress from myocardiocytes to macrophages is pivotal for the pathogenesis of CVB3-induced viral myocarditis. Sci Rep. 2017;7:42162 pubmed 出版商

Ji X, Chen Y, Ye G, Dong M, Lin K, Han J, et al. Detection of RAGE expression and its application to diabetic wound age estimation. Int J Legal Med. 2017;131:691-698 pubmed 出版商

Zhang Y, Yu J, Grachtchouk V, Qin T, Lumeng C, Sartor M, et al. Genomic binding of PAX8-PPARG fusion protein regulates cancer-related pathways and alters the immune landscape of thyroid cancer. Oncotarget. 2017;8:5761-5773 pubmed 出版商

Du M, Wang X, Tan X, Li X, Huang D, Huang K, et al. Nkx2-5 Is Expressed in Atherosclerotic Plaques and Attenuates Development of Atherosclerosis in Apolipoprotein E-Deficient Mice. J Am Heart Assoc. 2016;5: pubmed

Lizardo K, Almonte V, Law C, Aiyyappan J, Cui M, Nagajyothi J. Diet regulates liver autophagy differentially in murine acute Trypanosoma cruzi infection. Parasitol Res. 2017;116:711-723 pubmed 出版商

Tian S, Li C, Ran R, Chen S. Surfactant protein A deficiency exacerbates renal interstitial fibrosis following obstructive injury in mice. Biochim Biophys Acta Mol Basis Dis. 2017;1863:509-517 pubmed 出版商

Cox A, Barrandon O, Cai E, Rios J, Chavez J, Bonnyman C, et al. Resolving Discrepant Findings on ANGPTL8 in ?-Cell Proliferation: A Collaborative Approach to Resolving the Betatrophin Controversy. PLoS ONE. 2016;11:e0159276 pubmed 出版商

Khullar S, Katebi N, Herlofson B, Tvedt D, Olsen B. Evidence to support the hypothesis of tuberculosis as a cause of extreme osteonecrosis and osteomyelitis of the mandible in a West African population. Int J Oral Maxillofac Surg. 2016;45:1600-1606 pubmed 出版商

Akashi K, Saegusa J, Sendo S, Nishimura K, Okano T, Yagi K, et al. Knockout of endothelin type B receptor signaling attenuates bleomycin-induced skin sclerosis in mice. Arthritis Res Ther. 2016;18:113 pubmed 出版商

Vance M, Llanga T, Bennett W, Woodard K, Murlidharan G, Chungfat N, et al. AAV Gene Therapy for MPS1-associated Corneal Blindness. Sci Rep. 2016;6:22131 pubmed 出版商

Phinney D, Di Giuseppe M, Njah J, Sala E, Shiva S, St Croix C, et al. Mesenchymal stem cells use extracellular vesicles to outsource mitophagy and shuttle microRNAs. Nat Commun. 2015;6:8472 pubmed 出版商

Hanot Mambres D, Machelart A, Vanderwinden J, De Trez C, Ryffel B, Letesson J, et al. In Situ Characterization of Splenic Brucella melitensis Reservoir Cells during the Chronic Phase of Infection in Susceptible Mice. PLoS ONE. 2015;10:e0137835 pubmed 出版商

Brown A, Simmen R, Raj V, Van T, MacLeod S, Simmen F. Krüppel-like factor 9 (KLF9) prevents colorectal cancer through inhibition of interferon-related signaling. Carcinogenesis. 2015;36:946-55 pubmed 出版商

Malik I, Stange I, Martius G, Cameron S, Rave Fränk M, Hess C, et al. Role of PECAM-1 in radiation-induced liver inflammation. J Cell Mol Med. 2015;19:2441-52 pubmed 出版商

Hiemstra I, Vrijland K, Hogenboom M, Bouma G, Kraal G, den Haan J. Intestinal epithelial cell transported TLR2 ligand stimulates Ly6C⁺ monocyte differentiation in a G-CSF dependent manner. Immunobiology. 2015;220:1255-65 pubmed 出版商

Fukuda M, Aoki T, Manabe T, Maekawa A, Shirakawa T, Kataoka H, et al. Exacerbation of intracranial aneurysm and aortic dissection in hypertensive rat treated with the prostaglandin F-receptor antagonist AS604872. J Pharmacol Sci. 2014;126:230-42 pubmed

Lu H, Tzeng T, Liou S, Chang C, Yang C, Wu M, et al. Ruscogenin ameliorates experimental nonalcoholic steatohepatitis via suppressing lipogenesis and inflammatory pathway. Biomed Res Int. 2014;2014:652680 pubmed 出版商

Droguett A, Krall P, Burgos M, Valderrama G, Carpio D, Ardiles L, et al. Tubular overexpression of gremlin induces renal damage susceptibility in mice. PLoS ONE. 2014;9:e101879 pubmed 出版商

Majumder M, Xin X, Liu L, Girish G, Lala P. Prostaglandin E2 receptor EP4 as the common target on cancer cells and macrophages to abolish angiogenesis, lymphangiogenesis, metastasis, and stem-like cell functions. Cancer Sci. 2014;105:1142-51 pubmed 出版商

Suga H, Rennert R, Rodrigues M, Sorkin M, Glotzbach J, Januszyk M, et al. Tracking the elusive fibrocyte: identification and characterization of collagen-producing hematopoietic lineage cells during murine wound healing. Stem Cells. 2014;32:1347-60 pubmed 出版商

Martinod K, Demers M, Fuchs T, Wong S, Brill A, Gallant M, et al. Neutrophil histone modification by peptidylarginine deiminase 4 is critical for deep vein thrombosis in mice. Proc Natl Acad Sci U S A. 2013;110:8674-9 pubmed 出版商

Wintges K, Beil F, Albers J, Jeschke A, Schweizer M, Claass B, et al. Impaired bone formation and increased osteoclastogenesis in mice lacking chemokine (C-C motif) ligand 5 (Ccl5). J Bone Miner Res. 2013;28:2070-80 pubmed 出版商

Sekine C, Koyanagi A, Koyama N, Hozumi K, Chiba S, Yagita H. Differential regulation of osteoclastogenesis by Notch2/Delta-like 1 and Notch1/Jagged1 axes. Arthritis Res Ther. 2012;14:R45 pubmed 出版商

Hufford M, Kim T, Sun J, Braciale T. Antiviral CD8+ T cell effector activities in situ are regulated by target cell type. J Exp Med. 2011;208:167-80 pubmed 出版商

Thompson J, Chu Y, Glass J, Tapp A, Brown S. The manganese superoxide dismutase mimetic, M40403, protects adult mice from lethal total body irradiation. Free Radic Res. 2010;44:529-40 pubmed 出版商

Thompson J, Chu Y, Glass J, Brown S. Absence of IL-23p19 in donor allogeneic cells reduces mortality from acute GVHD. Bone Marrow Transplant. 2010;45:712-22 pubmed 出版商

Dewals B, Hoving J, Leeto M, Marillier R, Govender U, Cutler A, et al. IL-4Ralpha responsiveness of non-CD4 T cells contributes to resistance in schistosoma mansoni infection in pan-T cell-specific IL-4Ralpha-deficient mice. Am J Pathol. 2009;175:706-16 pubmed 出版商

Siegemund S, Hartl A, von Buttlar H, Dautel F, Raue R, Freudenberg M, et al. Conventional bone marrow-derived dendritic cells contribute to toll-like receptor-independent production of alpha/beta interferon in response to inactivated parapoxvirus ovis. J Virol. 2009;83:9411-22 pubmed 出版商

Culshaw S, Millington O, Brewer J, McInnes I. Murine neutrophils present Class II restricted antigen. Immunol Lett. 2008;118:49-54 pubmed 出版商

Chen H, ORDOG T, Chen J, YOUNG D, Bardsley M, Redelman D, et al. Differential gene expression in functional classes of interstitial cells of Cajal in murine small intestine. Physiol Genomics. 2007;31:492-509 pubmed

Noel G, Guo X, Wang Q, Schwemberger S, Byrum D, Ogle C. Postburn monocytes are the major producers of TNF-alpha in the heterogeneous splenic macrophage population. Shock. 2007;27:312-9 pubmed

de Jersey J, Snelgrove S, Palmer S, Teteris S, Mullbacher A, Miller J, et al. Beta cells cannot directly prime diabetogenic CD8 T cells in nonobese diabetic mice. Proc Natl Acad Sci U S A. 2007;104:1295-300 pubmed

Chen H, Redelman D, Ro S, Ward S, ORDOG T, Sanders K. Selective labeling and isolation of functional classes of interstitial cells of Cajal of human and murine small intestine. Am J Physiol Cell Physiol. 2007;292:C497-507 pubmed

Hewitson J, Jenkins G, Hamblin P, Mountford A. CD40/CD154 interactions are required for the optimal maturation of skin-derived APCs and the induction of helminth-specific IFN-gamma but not IL-4. J Immunol. 2006;177:3209-17 pubmed

Rempel J, Quina L, Blakely Gonzales P, Buchmeier M, Gruol D. Viral induction of central nervous system innate immune responses. J Virol. 2005;79:4369-81 pubmed

Reissinger A, Skinner J, Yuk M. Downregulation of mitogen-activated protein kinases by the Bordetella bronchiseptica Type III secretion system leads to attenuated nonclassical macrophage activation. Infect Immun. 2005;73:308-16 pubmed

Jennings J, Linderman D, Hu B, Sonstein J, Curtis J. Monocytes recruited to the lungs of mice during immune inflammation ingest apoptotic cells poorly. Am J Respir Cell Mol Biol. 2005;32:108-17 pubmed

Mischenko V, Kapina M, Eruslanov E, Kondratieva E, Lyadova I, Young D, et al. Mycobacterial dissemination and cellular responses after 1-lobe restricted tuberculosis infection of genetically susceptible and resistant mice. J Infect Dis. 2004;190:2137-45 pubmed

ORDOG T, Redelman D, Horváth V, Miller L, Horowitz B, Sanders K. Quantitative analysis by flow cytometry of interstitial cells of Cajal, pacemakers, and mediators of neurotransmission in the gastrointestinal tract. Cytometry A. 2004;62:139-49 pubmed

Mangan N, Fallon R, Smith P, Van Rooijen N, McKenzie A, Fallon P. Helminth infection protects mice from anaphylaxis via IL-10-producing B cells. J Immunol. 2004;173:6346-56 pubmed

Zheng S, Jiang J, Shen H, Chen Y. Reduced apoptosis and ameliorated listeriosis in TRAIL-null mice. J Immunol. 2004;173:5652-8 pubmed

Mattner J, Wandersee Steinhäuser A, Pahl A, Rollinghoff M, Majeau G, Hochman P, et al. Protection against progressive leishmaniasis by IFN-beta. J Immunol. 2004;172:7574-82 pubmed

Schleicher U, Mattner J, Blos M, Schindler H, Rollinghoff M, Karaghiosoff M, et al. Control of Leishmania major in the absence of Tyk2 kinase. Eur J Immunol. 2004;34:519-29 pubmed

Eruslanov E, Majorov K, Orlova M, Mischenko V, Kondratieva T, Apt A, et al. Lung cell responses to M. tuberculosis in genetically susceptible and resistant mice following intratracheal challenge. Clin Exp Immunol. 2004;135:19-28 pubmed

Cook A, Braine E, Hamilton J. The phenotype of inflammatory macrophages is stimulus dependent: implications for the nature of the inflammatory response. J Immunol. 2003;171:4816-23 pubmed

Reading P, Smith G. A kinetic analysis of immune mediators in the lungs of mice infected with vaccinia virus and comparison with intradermal infection. J Gen Virol. 2003;84:1973-83 pubmed

Blos M, Schleicher U, Soares Rocha F, Meissner U, Rollinghoff M, Bogdan C. Organ-specific and stage-dependent control of Leishmania major infection by inducible nitric oxide synthase and phagocyte NADPH oxidase. Eur J Immunol. 2003;33:1224-34 pubmed

Stavitsky A, Xianli J. In vitro and in vivo regulation by macrophage migration inhibitory factor (MIF) of expression of MHC-II, costimulatory, adhesion, receptor, and cytokine molecules. Cell Immunol. 2002;217:95-104 pubmed

Saio M, Radoja S, Marino M, Frey A. Tumor-infiltrating macrophages induce apoptosis in activated CD8(+) T cells by a mechanism requiring cell contact and mediated by both the cell-associated form of TNF and nitric oxide. J Immunol. 2001;167:5583-93 pubmed

Radoja S, Saio M, Frey A. CD8+ tumor-infiltrating lymphocytes are primed for Fas-mediated activation-induced cell death but are not apoptotic in situ. J Immunol. 2001;166:6074-83 pubmed