这是一篇有关淀粉样蛋白前体 (APP) 的综述，是根据16篇发表使用所有方法的文章归纳的。这综述旨在帮助来邦网的访客找到最适合淀粉样蛋白前体 抗体。
淀粉样蛋白前体 同义词: AAA; ABETA; ABPP; AD1; APPI; CTFgamma; CVAP; PN-II; PN2; alzheimer disease amyloid protein; amyloid beta A4 protein; beta-amyloid peptide; cerebral vascular amyloid peptide; peptidase nexin-II; preA4; protease nexin-II
EMD MilliporeEMD Millipore 淀粉样蛋白前体 产品
- 为了研究丝氨酸蛋白酶HtrA1在淀粉样前趋蛋白质加工中的功能,采用了Millipore的抗APP amyloid-β 1-16小鼠单克隆抗体进行了免疫组化实验。 (目录编号: MAB5206)
- 为了研究通过定量蛋白质组学发现新的BACE1底物，采用Chemicon的APP抗体以1:1,000稀释进行蛋白印迹实验。
- 为了研究通过定量蛋白质组学发现新的BACE1底物，采用Calbiochem的APP抗体以1:1,000稀释进行蛋白印迹实验。
- 运用Millipore/Chemicon公司的淀粉状蛋白前体蛋白抗体进行免疫组织化学实验以研究白质tau样蛋白病在额颞(骨)小叶退化中的作用。
- 为了研究神经元凋亡死亡中神经生长因子或脑源性生长因子信号的作用，采用了Chemicon的抗APP单抗进行免疫印迹分析。
- 为了研究四个CLD在STAS区引发的突变致病的分子机制，采用了Novagen的His6 抗体进行免疫荧光试验。
Life Technologies CorporationLife Technologies Corporation 淀粉样蛋白前体 产品
EpitomicsEpitomics 淀粉样蛋白前体 产品
Sigma-Aldrich
Covance
- 为了研究酵母可以用来模仿Abeta的毒性以筛选可能的修饰基因，采用Covance的抗Beta Amyloid抗体以1:1,000浓度进行蛋白印迹实验。
- 为了说明Amyloid beta是天然免疫系统的抗菌肽，使用了Covance公司的Amyloid beta单抗(6E10, 1:2,000稀释)来进行免疫组化和免疫印记实验。
- 为了研究突变的Aβ肽段对血管淀粉样变性及薄壁组织沉积作用的调控作用，使用了Covance公司的antibody 6E10 来检测蛋白印迹试验中的APP蛋白。
- 为研究在培养细胞中淀粉样前蛋白的E693Δ突变对淀粉样蛋白β低聚物在胞内积聚现象的影响，以及其在促使内质网应激诱导的凋亡作用上所发挥的角色，将Signet Laboratories提供的单克隆抗淀粉样蛋白β抗体6E10用于免疫沉淀实验中。
- 为了研究神经元凋亡小体死亡过程中NGF或BDNF信号的作用，在细胞培养中使用了Signet的抗Aβ单抗。
文章列表
- Sebastian Treusch et al. (2011). "Functional Links Between A? Toxicity, Endocytic Trafficking, and Alzheimers Disease Risk Factors in Yeast.".PMID 22033521
- Stephanie J Soscia et al. (2010). "The Alzheimer's disease-associated amyloid beta-protein is an antimicrobial peptide".PMID 20209079
- Matthew L Hemming et al. (2009). "Identification of beta-secretase (BACE1) substrates using quantitative proteomics".PMID 20041192
- Zilai Wang et al. (2009). "Presynaptic and postsynaptic interaction of the amyloid precursor protein promotes peripheral and central synaptogenesis".PMID 19726636
- Thomas Walther et al. (2009). "Improved learning and memory in aged mice deficient in amyloid beta-degrading neutral endopeptidase".PMID 19240795
- Martin C Herzig et al. (2009). "E22Q-mutant Abeta peptide (AbetaDutch) increases vascular but reduces parenchymal Abeta deposition".PMID 19218342
- Kazuchika Nishitsuji et al. (2009). "The E693Delta mutation in amyloid precursor protein increases intracellular accumulation of amyloid beta oligomers and causes endoplasmic reticulum stress-induced apoptosis in cultured cells".PMID 19164507
- Gabor G Kovacs et al. (2008). "White matter tauopathy with globular glial inclusions: a distinct sporadic frontotemporal lobar degeneration".PMID 18800011
- Rafael Mattera et al. (2008). "Ubiquitin binding and conjugation regulate the recruitment of Rabex-5 to early endosomes".PMID 18772883
- Carmela Matrone et al. (2008). "NGF and BDNF signaling control amyloidogenic route and Abeta production in hippocampal neurons".PMID 18728191
- Michael R Dorwart et al. (2008). "Congenital chloride-losing diarrhea causing mutations in the STAS domain result in misfolding and mistrafficking of SLC26A3".PMID 18216024
- Cristina Caballero et al. (2007). "Inter-individual variability in the expression of the mutated form of hPS1M146L determined the production of Abeta peptides in the PS1xAPP transgenic mice".PMID 17243176
- Brent L Kelly et al. (2005). "Beta-amyloid-induced dynamin 1 depletion in hippocampal neurons. A potential mechanism for early cognitive decline in Alzheimer disease".PMID 16002400
- Sandra Grau et al. (2005). "Implications of the serine protease HtrA1 in amyloid precursor protein processing".PMID 15855271
- Martin Ingelsson et al. (2004). "Lack of association of the cholesterol 24-hydroxylase (CYP46) intron 2 polymorphism with Alzheimer's disease".PMID 15331159
- Steffen Rossner et al. (2004). "Munc13-1-mediated vesicle priming contributes to secretory amyloid precursor protein processing".PMID 15123597