这是一篇有关Akt的综述,是根据141篇发表使用所有方法的文章归纳的。这综述旨在帮助来邦网的访客找到最适合Akt 抗体。
Akt 同义词: AKT; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA; PKB alpha; RAC-PK-alpha; RAC-alpha serine/threonine-protein kinase; protein kinase B alpha; proto-oncogene c-Akt; rac protein kinase alpha

  • 为了研究磷酸化的Akt对后囊的作用采用了Santa Cruz公司的抗pAkt抗体(1:350稀释)来进行免疫组化实验。
  • 为了研究ClipR-59介导的Akt细胞内区室化对脂肪细胞葡萄糖运输的调节作用,使用了Millipore公司的兔抗Akt和抗磷酸化Akt抗体来进行免疫印迹分析和免疫沉淀实验。
  • 为研究RhoE在角质化细胞的分化和层化过程中所发挥的角色,将密理博公司提供的小鼠单克隆抗Rac抗体(23A8)用于蛋白免疫印迹实验中。
Santa Cruz BiotechnologySanta Cruz Biotechnology Akt 产品
  • 为了研究MMP-10和CTSF在糖尿病患者角膜伤口治愈不良中的作用,采用了Santa Cruz Biotechnology的抗磷酸化-Akt(Ser473)抗体进行免疫组化试验。 (目录编号: sc-7985-R)
  • 为了研究在气喘患者中由TGFbeta和IL-10抑制造成的对T细胞的抗性的信号传导机制,采用了Santa Cruze Biotechnology的抗AKT抗体进行了流式细胞检测。
  • 为了研究STAT3/p63/Notch信号通路在调节小鼠和人的细胞分化中的功能,采用了Santa Cruz Biotechnology公司的TAKT抗体,进行了蛋白质印迹实验。
  • 为了研究mTOR通路对Notch信号通路和细胞分化的调节作用,使用了Santa Cruz Biotechnology公司的抗AKT抗体来进行免疫印迹分析。
  • 为了研究Ischaemic预处理在调节缺血再灌注过程中蛋白酶体的活性和pkcdelta降解中的作用,采用了Santa Cruz Biotechnology公司的多克隆抗Akt抗体产品,进行了免疫印迹实验。
  • 为了研究神经胶原发生和H-IL-6激活的神经发生途径,使用了Santa Cruz公司的phospho-AKT抗体来进行蛋白印迹实验。
  • 为了研究神经胶原发生和H-IL-6激活的神经发生途径,使用了Santa Cruz公司的AKT抗体来进行蛋白印迹实验。
  • 为了证明p130Cas的磷酸化促使了Rac的激活和膜起皱,采用了Santa Cruz Biotechnology的抗Rac抗体,进行免疫细胞化学实验
  • 为了研究miR-126对血管完整性和血管生成的调控作用,采用了Santa Cruz的抗AKT1抗体进行免疫印迹实验。
  • 兔源性抗磷酸化Akt(Ser473)多克隆抗体(Santa Cruz)可用于免疫组化实验,来研究胰岛素样生长因子-1过表达在乳腺癌组织中的作用(标本均取自BK5.IGF-1转基因小鼠体内人工致癌乳腺组织,并经福尔马林固定)。
  • 为了研究VHL肿瘤抑制基因通过成纤维细胞生长因子受体信号通路对内皮功能的影响,采用了Santa Cruz的兔多抗ETS1抗体进行免疫印迹实验。
  • 兔源性抗丝氨酸Akt 1/2 和磷酸化丝氨酸p-Akt 1/2/3 (Thr 308)多克隆抗体(Santa Cruz)可用于免疫印迹实验,来研究肿瘤抑制基因TSC1和TSC2及其它因子在鳞状细胞癌致癌过程中的作用。
  • 为了检测蛋白酶体抑制剂和组蛋白酰基转移酶抑制剂在GBM细胞株中产生的效应,采用了Santa Cruz Biotechnology的兔抗磷酸化Akt多抗,进行蛋白质印迹实验
  • 为了研究人类疱疹病毒8趋化因子内皮生存和病毒复制中的作用,采用了Santa Cruz生物技术公司的抗AKT抗体进行了蛋白印迹实验。
  • 为了研究生长激素释放激素MZ-J-7-138和JV-1-92对抗物生长对H460人体非小细胞肺癌常位异种嫁接入裸鼠的影响,使用了Santa Cruz Biotechnology公司的多克隆Akt1抗体,进行了免疫印迹实验。
  • 在免疫印迹实验中使用了Santa Cruz Biotechnology公司的抗Akt抗体用于研究溶血磷脂酸酰基转移酶β对正常细胞增殖和存活信号及肿瘤细胞凋亡的抑制作用。
  • 在免疫印迹实验中使用了Santa Cruz Biotechnology公司的抗Akt抗体用于研究在中胚层细胞分化的转变中EWS/FLI-1的作用。
赛信通(上海)生物试剂有限公司赛信通(上海)生物试剂有限公司 Akt 产品
  • 为了研究MMP-10和CTSF在糖尿病患者角膜伤口治愈不良中的作用,采用了Cell Signaling的抗磷酸化-Akt(Ser473)抗体进行免疫组化试验。
  • 为了研究泡状H+-ATPase参与到mTOR通路中mTORC1的转位和激活,采用Cell Signaling的抗Akt和抗S473磷酸化Akt抗体进行蛋白印迹实验。
  • 为了研究人血糖过低可由激活状态的AKT2突变体引起,采用了Cell Signaling Technologies的抗AKT抗体进行蛋白印迹实验。
  • 为了研究溶酶体形成能够被TFEB调控并导致细胞自噬,采用Cell Signaling的抗磷酸化AKT抗体进行蛋白印迹实验。
  • 为了研究去氢表雄酮和神经生长因子受体之间的相互作用,采用了Cell Signaling公司的抗AKT (9272,1:500)和抗磷酸化AKT(Ser473) (9271,1:500)抗体进行了免疫印记实验。
  • 为了研究肺部发炎部位slit2对嗜酸性粒细胞和嗜中性粒细胞的影响,采用了Cell Signaling Technology公司的抗Akt抗体进行免疫印迹实验。
  • 为了研究在肥胖过程中Sfrp5作为抗炎脂肪因子在调节代谢异常过程中的功能,使用了Cell Signaling Technology公司的抗磷酸化Akt和抗Akt抗体来进行免疫印迹分析。
  • 为了研究LMP2A在鼻咽癌进展中的作用,采用了Cell Signaling的抗Akt抗体进行了免疫印迹实验。
  • 为了研究4E-BPs对mTORC1信号通路的精确调控,使用了Cell Signaling Technology公司的抗Akt和抗磷酸化Akt抗体来进行免疫印迹分析。
  • 为了研究多发性骨髓瘤中细胞周期蛋白K和细胞周期蛋白D1b的作用,采用了Cell Signaling的抗AKT和抗磷酸化AKT (Thr308)抗体进行免疫印迹实验。
  • 为了研究SPRR3在结直肠癌肿瘤形成中的作用,采用了Cell Signaling的抗AKT的抗体进行了免疫印记实验。
  • 为了为了说明多囊蛋白1可以激活结节性硬化症2和抑制mTOR,使用了Cell Signaling Technology公司的抗AKT和抗磷酸化AKT抗体来进行蛋白印迹实验。
  • 为了研究干扰素γ在人视网膜色素上皮细胞促血管作用的分子机制,以及磷酸肌醇3激酶/雷帕霉素靶(mammalian target of rapamycin,mTOR)蛋白转导途径在这个过程中的作用,采用了细胞信号技术公司的Akt抗体进行了蛋白印迹实验。
  • 为了制备单克隆抗体来对胰腺肿瘤中作用于EphA2的治疗潜能进行评估,采用了Cell Signalling Technology公司的抗Akt抗体和抗磷酸化的Akt抗体,进行了蛋白质印迹实验。
  • 为了研究STAT3/p63/Notch信号通路在调节小鼠和人的细胞分化中的功能,采用了Cell Signaling Technology公司的p-AKT抗体,进行了蛋白质印迹实验。
  • 为了研究mTOR通路对Notch信号通路和细胞分化的调节作用,使用了Cell Signaling Technology公司的磷酸化AKT抗体来进行免疫印迹分析。
  • 为了研究表皮生长因子突变常常与肿瘤发生有关,研究了Akt介导的在表皮生长因子诱导下固醇调节结合蛋白1的切割以及移位机理,并发现了一种新的治疗由于表皮生长因子激活的胶质母细胞瘤,采用了Cell Signaling公司p-Akt苏氨酸308抗体,进行免疫化学荧光实验。
  • 为了研究Tsc/mTORC1信号通路在调控原卵泡休眠和活化中的作用,采用了Cell Signaling Technologies 公司的兔多克隆抗Akt抗体产品,进行了免疫印迹实验
  • 为了研究药物洗脱支架诱导自噬从而对内皮组织的修复进行抑制,采用了Cell Signaling的抗Akt和抗磷酸化Akt抗体进行免疫印迹实验。
  • 为了研究知母皂甙AIII对肿瘤细胞造成细胞毒性的机制,使用了Cell Signaling公司的抗Akt抗体来进行蛋白印迹分析。
  • 为了推断钙调磷酸酶活性和白血病细胞凋亡能够通过糖皮质激素介导上调的RCAN1-1来调节,使用了Cell Signaling Technology公司的磷酸化抗体Akt来进行免疫印迹分析。
  • 为了鉴定ERBB4基因的突变在黑素瘤中所起的作用,使用了Cell Signaling公司的磷酸化和非磷酸化抗体AKT来进行免疫印迹分析。
  • 为了研究PKCdelta在调节CHL1在星形胶质细胞中表达的作用,采用了 Cell Signaling Technology公司的抗磷酸化Akt(Ser473) 抗体产品(1:1000),进行了免疫印迹实验。
  • 为了研究在人的近曲小管细胞中GRK4对于D3受体信号传导的重要作用,使用了Cell Signaling公司的抗磷酸化AKT抗体进行免疫印迹实验。
  • 为了研究rpS6磷酸化在调控肌肉纤维生长和能量储存中的作用,采用了Cell Signaling Technology公司的Akt抗体产品,进行了免疫印迹实验。
  • 为了研究sproutys在调控小鼠血管生成和局部缺血中的作用,采用了Cell Signaling Technology公司的抗磷酸化Akt抗体产品,进行了免疫印迹实验。
  • 为了研究ARIA在调控内皮细胞凋亡和血管生成中的作用,采用了Cell Signaling公司的抗磷酸化Akt抗体产品,进行了免疫印迹实验。
  • 为了研究PTEN在调控前列腺损伤生长中的作用,采用Cell Signaling Technologies公司的苏氨酸308位磷酸化AKT抗体产品1:1000,进行了免疫印迹实验。
  • 为了研究Prdx1在调控肿瘤发生中的作用,采用了Cell Signaling公司的抗Akt抗体产品,进行了免疫印迹实验。
  • 为了说明脂联素单倍不足可以通过抑制PTEN抑癌因子的活性和激活PI3K/Akt信号通路来促进乳腺肿瘤的发生,使用了Cell Signaling Biotechnology公司的抗Akt和抗磷酸化Akt抗体来进行蛋白印迹实验。
  • 为证实JNK1可以抑制脂多糖诱导的金属蛋白酶9的表达,使用了Cell Signaling公司的抗p-Akt抗体来进行蛋白印迹分析。
  • 为了说明整合素连接的激酶可以调控气道平滑肌细胞分化,使用了Abcam公司的抗Akt抗体进行蛋白印迹实验。
  • 为了研究MMP-10和CTSF在糖尿病患者角膜伤口治愈不良中的作用,采用了BD Transduction Labs的抗Akt抗体进行免疫印迹试验。 (目录编号: 610860)
Sigma-Aldrich
  • 为了考察Dickkopfs (Dkks)和Kremen2 (Krm2)在胃肠道癌症中表达的变化,使用了Sigma-Aldrich 公司的抗Rac的小鼠抗人抗体进行了免疫组化实验。
Covance
  • 结合计算机模拟实验,模拟实验结果的检验,以及蛋白相互作用网络的反向工程实验来确认新的曲妥单抗抗乳腺癌的潜在治疗策略,将Covance提供的兔抗磷酸化AKT1抗体(目录号:PRB-542p)用于蛋白免疫印迹。
文章列表
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  2. K Hussain et al. (2011). "An Activating Mutation of AKT2 and Human Hypoglycemia.".PMID 21979934
  3. Carmine Settembre et al. (2011). "TFEB Links Autophagy to Lysosomal Biogenesis.".PMID 21617040
  4. Iakovos Lazaridis et al. (2011). "Neurosteroid Dehydroepiandrosterone Interacts with Nerve Growth Factor (NGF) Receptors, Preventing Neuronal Apoptosis.".PMID 21541365
  5. Heather L Chandler et al. (2010). "The effect of phosphorylated Akt inhibition on posterior capsule opacification in an ex vivo canine model".PMID 21139685
  6. Noriyuki Ouchi et al. (2010). "Sfrp5 Is an Anti-Inflammatory Adipokine That Modulates Metabolic Dysfunction in Obesity.".PMID 20558665
  7. Qing Li Kong et al. (2010). "Epstein-Barr virus-encoded LMP2A induces an epithelial-mesenchymal transition and increases the number of side population stem-like cancer cells in nasopharyngeal carcinoma".PMID 20532215
  8. Ryan J O Dowling et al. (2010). "mTORC1-mediated cell proliferation, but not cell growth, controlled by the 4E-BPs.".PMID 20508131
  9. Veronique Marsaud et al. (2010). "Cyclin K and cyclin D1b are oncogenic in myeloma cells".PMID 20459741
  10. Dong Hyung Cho et al. (2010). "Upregulation of SPRR3 promotes colorectal tumorigenesis".PMID 20379613
  11. Ruhee Dere et al. (2010). "Carboxy Terminal Tail of Polycystin-1 Regulates Localization of TSC2 to Repress mTOR".PMID 20169078
  12. Baoying Liu et al. (2010). "Pro-angiogenic effect of IFNgamma is dependent on the PI3K/mTOR/translational pathway in human retinal pigmented epithelial cells".PMID 20157617
  13. Helenia Ansuini et al. (2009). "Anti-EphA2 Antibodies with Distinct In Vitro Properties Have Equal In Vivo Efficacy in Pancreatic Cancer".PMID 20130824
  14. Jianhui Ma et al. (2010). "Mammalian target of rapamycin regulates murine and human cell differentiation through STAT3/p63/Jagged/Notch cascade".PMID 20038814
  15. Deliang Guo et al. (2009). "EGFR Signaling Through an Akt-SREBP-1-Dependent, Rapamycin-Resistant Pathway Sensitizes Glioblastomas to Antilipogenic Therapy".PMID 20009104
  16. Deepak Adhikari et al. (2010). "Tsc/mTORC1 signaling in oocytes governs the quiescence and activation of primordial follicles".PMID 19843540
  17. Mehrnoosh Saghizadeh et al. (2010). "Adenovirus-driven overexpression of proteinases in organ-cultured normal human corneas leads to diabetic-like changes".PMID 19828126
  18. Eric N Churchill et al. (2010). "Ischaemic preconditioning improves proteasomal activity and increases the degradation of {delta}PKC during reperfusion".PMID 19820255
  19. Shin Ichiro Hayashi et al. (2009). "The stent-eluting drugs sirolimus and paclitaxel suppress healing of the endothelium by induction of autophagy".PMID 19815708
  20. Frank W King et al. (2009). "Timosaponin AIII is preferentially cytotoxic to tumor cells through inhibition of mTOR and induction of ER stress".PMID 19789631
  21. Yasuko Hirakawa et al. (2009). "Glucocorticoid evoked upregulation of RCAN1-1 in human leukemic CEM cells susceptible to apoptosis".PMID 19725972
  22. Todd D Prickett et al. (2009). "Analysis of the tyrosine kinome in melanoma reveals recurrent mutations in ERBB4".PMID 19718025
  23. Junfang Wu et al. (2010). "Phosphatidylinositol 3-kinase/protein kinase Cdelta activation induces close homolog of adhesion molecule L1 (CHL1) expression in cultured astrocytes".PMID 19672967
  24. Van Anthony M Villar et al. (2009). "G protein-coupled receptor kinase 4 (GRK4) regulates the phosphorylation and function of the dopamine D3 receptor".PMID 19520868
  25. Igor Ruvinsky et al. (2009). "Mice Deficient in Ribosomal Protein S6 Phosphorylation Suffer from Muscle Weakness that Reflects a Growth Defect and Energy Deficit".PMID 19479038
  26. Koji Taniguchi et al. (2009). "Suppression of Sproutys has a therapeutic effect for a mouse model of ischemia by enhancing angiogenesis".PMID 19424491
  27. Koji Ikeda et al. (2009). "Identification of ARIA regulating endothelial apoptosis and angiogenesis by modulating proteasomal degradation of cIAP-1 and cIAP-2".PMID 19416853
  28. Jorge Blando et al. (2009). "PTEN deficiency is fully penetrant for prostate adenocarcinoma in C57BL/6 mice via mTOR-dependent growth".PMID 19395652
  29. Juxiang Cao et al. (2009). "Prdx1 inhibits tumorigenesis via regulating PTEN/AKT activity".PMID 19369943
  30. Janice B B Lam et al. (2009). "Adiponectin haploinsufficiency promotes mammary tumor development in MMTV-PyVT mice by modulation of phosphatase and tensin homolog activities".PMID 19319191
  31. Yun Song Lee et al. (2009). "Regulation of expression of matrix metalloproteinase-9 by JNK in Raw 264.7 cells: presence of inhibitory factor(s) suppressing MMP-9 induction in serum and conditioned media".PMID 19299915
  32. Kyuho Jeong et al. (2009). "Modulation of the caveolin-3 localization to caveolae and STAT3 to mitochondria by catecholamine-induced cardiac hypertrophy in H9c2 cardiomyoblasts".PMID 19299911
  33. Tracie A Seimon et al. (2009). "Macrophage deficiency of p38alpha MAPK promotes apoptosis and plaque necrosis in advanced atherosclerotic lesions in mice".PMID 19287091
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  35. Young Jun Kim et al. (2009). "NDRG2 expression decreases with tumor stages and regulates TCF/{beta}-catenin signaling in human colon carcinoma".PMID 19237607
  36. Anne Catherine Sprynski et al. (2009). "The role of IGF-1 as a major growth factor for myeloma cell lines and the prognostic relevance of the expression of its receptor".PMID 19228610
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  51. D Chaturvedi et al. (2009). "Rapamycin induces transactivation of the EGFR and increases cell survival".PMID 19151764
  52. Trupti Joshi et al. (2009). "The PtdIns 3-kinase/Akt pathway regulates macrophage-mediated ADCC against B cell lymphoma".PMID 19148288
  53. Flora Brozzi et al. (2009). "S100B Protein Regulates Astrocyte Shape and Migration via Interaction with Src Kinase: IMPLICATIONS FOR ASTROCYTE DEVELOPMENT, ACTIVATION, AND TUMOR GROWTH".PMID 19147496
  54. Jixin Ding et al. (2009). "ClipR-59 interacts with Akt and regulates Akt cellular compartmentalization".PMID 19139280
  55. Ozgur Sahin et al. (2009). "Modeling ERBB receptor-regulated G1/S transition to find novel targets for de novo trastuzumab resistance".PMID 19118495
  56. Xia V Yang et al. (2009). "Activated protein C ligation of ApoER2 (LRP8) causes Dab1-dependent signaling in U937 cells".PMID 19116273
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  58. Price Blair et al. (2009). "Stimulation of Toll-like receptor 2 in human platelets induces a thromboinflammatory response through activation of phosphoinositide 3-kinase".PMID 19106411
  59. James W Peacock et al. (2009). "PTEN loss promotes mitochondrially dependent type II Fas-induced apoptosis via PEA-15".PMID 19103758
  60. Judit Pallares et al. (2009). "CK2beta is expressed in endometrial carcinoma and has a role in apoptosis resistance and cell proliferation".PMID 19056846
  61. Hiroshi Honda et al. (2008). "Serial analysis of gene expression reveals differential expression between endometriosis and normal endometrium. Possible roles for AXL and SHC1 in the pathogenesis of endometriosis".PMID 19055724
  62. Ilona Patursky Polischuk et al. (2009). "The TSC-mTOR pathway mediates translational activation of TOP mRNAs by insulin largely in a raptor- or rictor-independent manner".PMID 19047368
  63. Xue Qing Wang et al. (2009). "Oncogenic K-Ras regulates proliferation and cell junctions in lung epithelial cells through induction of cyclooxygenase-2 and activation of metalloproteinase-9".PMID 19037103
  64. Xinqiang Huang et al. (2009). "Resident hepatocyte fibroblast growth factor receptor 4 limits hepatocarcinogenesis".PMID 19009564
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