这是一篇来自已证抗体库的有关人类 KMT2A的综述,是根据13篇发表使用所有方法的文章归纳的。这综述旨在帮助来邦网的访客找到最适合KMT2A 抗体。
KMT2A 同义词: ALL-1; CXXC7; HRX; HTRX1; MLL; MLL1; MLL1A; TRX1; WDSTS; histone-lysine N-methyltransferase 2A; CXXC-type zinc finger protein 7; lysine (K)-specific methyltransferase 2A; lysine N-methyltransferase 2A; mixed lineage leukemia 1; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); trithorax-like protein; zinc finger protein HRX

Bethyl
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  • 免疫沉淀; 人类; 1:200; 图 8g
  • 免疫印迹; 人类; 1:200; 图 9a,9b
Bethyl KMT2A抗体(Bethyl, A300-374A)被用于被用于免疫沉淀在人类样品上浓度为1:200 (图 8g) 和 被用于免疫印迹在人类样品上浓度为1:200 (图 9a,9b). Nat Commun (2017) ncbi
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  • 免疫沉淀; 小鼠; 图 2
Bethyl KMT2A抗体(Bethyl, A300-086A)被用于被用于免疫沉淀在小鼠样品上 (图 2). Epigenetics Chromatin (2016) ncbi
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  • 免疫印迹; 小鼠; 图 1c
Bethyl KMT2A抗体(Bethyl, A300-374A)被用于被用于免疫印迹在小鼠样品上 (图 1c). Nucleic Acids Res (2016) ncbi
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  • 免疫印迹; 人类; 图 s1e
Bethyl KMT2A抗体(Bethyl Laboratories, A300-086A)被用于被用于免疫印迹在人类样品上 (图 s1e). Genes Dev (2016) ncbi
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  • 染色质免疫沉淀 ; 人类; 图 s4
Bethyl KMT2A抗体(BETHYL, A300?C374A)被用于被用于染色质免疫沉淀 在人类样品上 (图 s4). Nat Commun (2015) ncbi
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  • 免疫印迹; 人类; 图 3b
Bethyl KMT2A抗体(Bethyl Laboratories, A300-086A)被用于被用于免疫印迹在人类样品上 (图 3b). Nature (2015) ncbi
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  • 免疫印迹; 人类; 图 8
Bethyl KMT2A抗体(Bethyl Laboratories, A300-086A)被用于被用于免疫印迹在人类样品上 (图 8). elife (2015) ncbi
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  • 免疫印迹; 人类; 图 2
Bethyl KMT2A抗体(Bethyl, A300-087A)被用于被用于免疫印迹在人类样品上 (图 2). Nat Struct Mol Biol (2015) ncbi
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  • 免疫沉淀; 人类; 图 3
Bethyl KMT2A抗体(Bethyl, A300-374A)被用于被用于免疫沉淀在人类样品上 (图 3). Nat Struct Mol Biol (2015) ncbi
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  • 免疫印迹; 小鼠; 图 s2, s4
Bethyl KMT2A抗体(Bethyl Laboratories, A300-086A)被用于被用于免疫印迹在小鼠样品上 (图 s2, s4). Development (2014) ncbi
圣克鲁斯生物技术
小鼠 单克隆(H-10)
  • 免疫印迹; 人类; 图 3
圣克鲁斯生物技术 KMT2A抗体(Santa Cruz, sc-374392)被用于被用于免疫印迹在人类样品上 (图 3). Oncotarget (2016) ncbi
GeneTex
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  • 免疫组化-石蜡切片; 小鼠; 1:400; 图 1b
GeneTex KMT2A抗体(GeneTax, GTX17959)被用于被用于免疫组化-石蜡切片在小鼠样品上浓度为1:400 (图 1b). Cancer Biol Ther (2016) ncbi
赛默飞世尔
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  • 免疫组化; 人类; 图 s2
赛默飞世尔 KMT2A抗体(Thermo Scientific, PA5-11264)被用于被用于免疫组化在人类样品上 (图 s2). PLoS Genet (2012) ncbi
Active Motif
小鼠 单克隆(N4.4)
  • 免疫印迹; 人类; 图 2
Active Motif KMT2A抗体(Active Motif, 39829)被用于被用于免疫印迹在人类样品上 (图 2). Nat Struct Mol Biol (2015) ncbi
赛信通(上海)生物试剂有限公司
单克隆(D2M7U)
  • 免疫沉淀; 人类; 图 s1f
  • 免疫细胞化学; 人类; 图 1e
  • 免疫印迹; 人类; 图 2d, s1b
赛信通(上海)生物试剂有限公司 KMT2A抗体(Cell Signaling, 14689)被用于被用于免疫沉淀在人类样品上 (图 s1f), 被用于免疫细胞化学在人类样品上 (图 1e) 和 被用于免疫印迹在人类样品上 (图 2d, s1b). Genes Dev (2019) ncbi
单克隆(D6G8N)
  • 免疫细胞化学; 人类; 图 s1d
  • 免疫印迹; 人类; 图 1d, 2d, s1b
赛信通(上海)生物试剂有限公司 KMT2A抗体(Cell Signaling, 14197)被用于被用于免疫细胞化学在人类样品上 (图 s1d) 和 被用于免疫印迹在人类样品上 (图 1d, 2d, s1b). Genes Dev (2019) ncbi
文章列表
  1. Zhao Z, Wang L, Volk A, Birch N, Stoltz K, Bartom E, et al. Regulation of MLL/COMPASS stability through its proteolytic cleavage by taspase1 as a possible approach for clinical therapy of leukemia. Genes Dev. 2019;33:61-74 pubmed 出版商
  2. Xu X, Fan Z, Liang C, Li L, Wang L, Liang Y, et al. A signature motif in LIM proteins mediates binding to checkpoint proteins and increases tumour radiosensitivity. Nat Commun. 2017;8:14059 pubmed 出版商
  3. Lin W, FRANCIS J, Li H, Gao X, Pedamallu C, Ernst P, et al. Kmt2a cooperates with menin to suppress tumorigenesis in mouse pancreatic islets. Cancer Biol Ther. 2016;17:1274-1281 pubmed 出版商
  4. Sun J, Zhao Y, McGreal R, Cohen Tayar Y, Rockowitz S, Wilczek C, et al. Pax6 associates with H3K4-specific histone methyltransferases Mll1, Mll2, and Set1a and regulates H3K4 methylation at promoters and enhancers. Epigenetics Chromatin. 2016;9:37 pubmed 出版商
  5. Oswald F, Rodriguez P, Giaimo B, Antonello Z, Mira L, Mittler G, et al. A phospho-dependent mechanism involving NCoR and KMT2D controls a permissive chromatin state at Notch target genes. Nucleic Acids Res. 2016;44:4703-20 pubmed 出版商
  6. Capell B, Drake A, Zhu J, Shah P, Dou Z, Dorsey J, et al. MLL1 is essential for the senescence-associated secretory phenotype. Genes Dev. 2016;30:321-36 pubmed 出版商
  7. Wu S, Yang Z, Ye R, An D, Li C, Wang Y, et al. Novel variants in MLL confer to bladder cancer recurrence identified by whole-exome sequencing. Oncotarget. 2016;7:2629-45 pubmed 出版商
  8. Tajima K, Yae T, Javaid S, Tam O, Comaills V, Morris R, et al. SETD1A modulates cell cycle progression through a miRNA network that regulates p53 target genes. Nat Commun. 2015;6:8257 pubmed 出版商
  9. Zhu J, Sammons M, Donahue G, Dou Z, Vedadi M, Getlik M, et al. Gain-of-function p53 mutants co-opt chromatin pathways to drive cancer growth. Nature. 2015;525:206-11 pubmed 出版商
  10. Thandapani P, Song J, Gandin V, Cai Y, Rouleau S, Garant J, et al. Aven recognition of RNA G-quadruplexes regulates translation of the mixed lineage leukemia protooncogenes. elife. 2015;4: pubmed 出版商
  11. Aguilar Arnal L, Katada S, Orozco Solis R, Sassone Corsi P. NAD(+)-SIRT1 control of H3K4 trimethylation through circadian deacetylation of MLL1. Nat Struct Mol Biol. 2015;22:312-8 pubmed 出版商
  12. Denissov S, Hofemeister H, Marks H, Kranz A, Ciotta G, Singh S, et al. Mll2 is required for H3K4 trimethylation on bivalent promoters in embryonic stem cells, whereas Mll1 is redundant. Development. 2014;141:526-37 pubmed 出版商
  13. Hopkin A, Gordon W, Klein R, Espitia F, Daily K, Zeller M, et al. GRHL3/GET1 and trithorax group members collaborate to activate the epidermal progenitor differentiation program. PLoS Genet. 2012;8:e1002829 pubmed 出版商