这是一篇来自已证抗体库的有关人类 TSC1的综述,是根据35篇发表使用所有方法的文章归纳的。这综述旨在帮助来邦网的访客找到最适合TSC1 抗体。
TSC1 同义词: LAM; TSC

赛默飞世尔
domestic rabbit 多克隆
  • 免疫组化; 小鼠; 1:500; 图 5c
  • 免疫印迹; 小鼠; 1:1000; 图 5a
赛默飞世尔 TSC1抗体(ThermoFisher, PA5-20131)被用于被用于免疫组化在小鼠样本上浓度为1:500 (图 5c) 和 被用于免疫印迹在小鼠样本上浓度为1:1000 (图 5a). Nature (2019) ncbi
domestic goat 多克隆
  • 免疫细胞化学基因敲除验证; 小鼠; 1:200; 图 1
  • 免疫印迹; 小鼠; 1:200; 图 1
赛默飞世尔 TSC1抗体(Pierce, PA5-18506)被用于被用于免疫细胞化学基因敲除验证在小鼠样本上浓度为1:200 (图 1) 和 被用于免疫印迹在小鼠样本上浓度为1:200 (图 1). Nat Commun (2016) ncbi
小鼠 单克隆(5C8A12)
  • 免疫印迹基因敲除验证; 小鼠; 图 1
赛默飞世尔 TSC1抗体(Invitrogen, 37-0400)被用于被用于免疫印迹基因敲除验证在小鼠样本上 (图 1). Cell Cycle (2015) ncbi
小鼠 单克隆(5C8A12)
  • 免疫印迹; 人类; 图 5
赛默飞世尔 TSC1抗体(Invitrogen, 37-0400)被用于被用于免疫印迹在人类样本上 (图 5). J Exp Med (2014) ncbi
小鼠 单克隆(5C8A12)
  • 免疫印迹; 人类; 图 1
赛默飞世尔 TSC1抗体(ZYMED, 37-0400)被用于被用于免疫印迹在人类样本上 (图 1). PLoS ONE (2012) ncbi
小鼠 单克隆(5C8A12)
  • 免疫印迹; 人类; 图 3
赛默飞世尔 TSC1抗体(Zymed, 37-0400)被用于被用于免疫印迹在人类样本上 (图 3). Genes Cells (2010) ncbi
小鼠 单克隆(5C8A12)
  • 免疫印迹; 人类; 图 4d
赛默飞世尔 TSC1抗体(Zymed, 37-0400)被用于被用于免疫印迹在人类样本上 (图 4d). Sci Signal (2010) ncbi
小鼠 单克隆(5C8A12)
  • 免疫细胞化学; 人类; 1:100; 图 1
  • 免疫印迹; 人类; 图 2
赛默飞世尔 TSC1抗体(Zymed, 37-0400)被用于被用于免疫细胞化学在人类样本上浓度为1:100 (图 1) 和 被用于免疫印迹在人类样本上 (图 2). Hum Mol Genet (2009) ncbi
小鼠 单克隆(5C8A12)
  • 免疫组化-石蜡切片; 人类; 1:70; 表 1
赛默飞世尔 TSC1抗体(Zymed, 5C8A12)被用于被用于免疫组化-石蜡切片在人类样本上浓度为1:70 (表 1). Neuropathology (2008) ncbi
小鼠 单克隆(5C8A12)
  • 免疫印迹; 小鼠; 图 4a
赛默飞世尔 TSC1抗体(Zymed, 37-0400)被用于被用于免疫印迹在小鼠样本上 (图 4a). Cell (2007) ncbi
安迪生物R&D
小鼠 单克隆(488915)
  • 免疫沉淀; 人类
安迪生物R&D TSC1抗体(R&D Systems, MAB4379)被用于被用于免疫沉淀在人类样本上. J Clin Invest (2015) ncbi
赛信通(上海)生物试剂有限公司
domestic rabbit 单克隆(D43E2)
  • 免疫印迹; 小鼠; 1:1000; 图 1c, s1a, 4d
赛信通(上海)生物试剂有限公司 TSC1抗体(CST, 6935)被用于被用于免疫印迹在小鼠样本上浓度为1:1000 (图 1c, s1a, 4d). Cell Rep (2022) ncbi
domestic rabbit 单克隆(D43E2)
  • 免疫印迹; 小鼠; 图 2a
赛信通(上海)生物试剂有限公司 TSC1抗体(Cell signaling, 6935)被用于被用于免疫印迹在小鼠样本上 (图 2a). Mol Metab (2022) ncbi
domestic rabbit 单克隆(D43E2)
  • 免疫印迹基因敲除验证; 小鼠; 图 3f
赛信通(上海)生物试剂有限公司 TSC1抗体(Cell Signaling, 6935)被用于被用于免疫印迹基因敲除验证在小鼠样本上 (图 3f). Cell Death Dis (2021) ncbi
domestic rabbit 多克隆
  • 免疫印迹; 人类; 图 2f
赛信通(上海)生物试剂有限公司 TSC1抗体(Cell Signaling Technology, 4906)被用于被用于免疫印迹在人类样本上 (图 2f). Nat Commun (2021) ncbi
domestic rabbit 单克隆(D43E2)
  • 免疫印迹; 小鼠; 1:1000; 图 s12
赛信通(上海)生物试剂有限公司 TSC1抗体(Cell Signaling, 6935)被用于被用于免疫印迹在小鼠样本上浓度为1:1000 (图 s12). Cell Death Dis (2021) ncbi
domestic rabbit 单克隆(D43E2)
  • 免疫印迹基因敲除验证; 小鼠; 1:200; 图 1a
赛信通(上海)生物试剂有限公司 TSC1抗体(Cell Signaling Technology, 6935)被用于被用于免疫印迹基因敲除验证在小鼠样本上浓度为1:200 (图 1a). Front Immunol (2021) ncbi
domestic rabbit 单克隆(D43E2)
  • 免疫印迹; 人类; 1:1000
赛信通(上海)生物试剂有限公司 TSC1抗体(Cell Signaling Technology, 6935)被用于被用于免疫印迹在人类样本上浓度为1:1000. Nat Commun (2021) ncbi
domestic rabbit 单克隆(D43E2)
  • 免疫印迹; 小鼠; 1:1000; 图 2b
赛信通(上海)生物试剂有限公司 TSC1抗体(Cell signaling, 6935)被用于被用于免疫印迹在小鼠样本上浓度为1:1000 (图 2b). elife (2019) ncbi
domestic rabbit 多克隆
  • 免疫印迹; 人类; 图 3a
赛信通(上海)生物试剂有限公司 TSC1抗体(Cell Signaling, 4906)被用于被用于免疫印迹在人类样本上 (图 3a). Sci Rep (2019) ncbi
domestic rabbit 多克隆
  • 免疫印迹; 人类; 图 ev3e
赛信通(上海)生物试剂有限公司 TSC1抗体(Cell Signaling, 4906)被用于被用于免疫印迹在人类样本上 (图 ev3e). EMBO J (2018) ncbi
domestic rabbit 多克隆
  • 其他; 人类; 图 4c
赛信通(上海)生物试剂有限公司 TSC1抗体(Cell Signaling, 4906)被用于被用于其他在人类样本上 (图 4c). Cancer Cell (2018) ncbi
domestic rabbit 单克隆(D43E2)
  • 免疫印迹; 小鼠; 图 3d
赛信通(上海)生物试剂有限公司 TSC1抗体(Cell Signaling, 6935)被用于被用于免疫印迹在小鼠样本上 (图 3d). Biochem Biophys Res Commun (2018) ncbi
domestic rabbit 多克隆
  • 免疫印迹; 小鼠; 图 1a
赛信通(上海)生物试剂有限公司 TSC1抗体(Cell Signaling, 4906)被用于被用于免疫印迹在小鼠样本上 (图 1a). Epilepsia (2017) ncbi
domestic rabbit 单克隆(D43E2)
  • 免疫印迹; 人类; 1:1000; 图 5a
赛信通(上海)生物试剂有限公司 TSC1抗体(Cell Signaling, 6935)被用于被用于免疫印迹在人类样本上浓度为1:1000 (图 5a). Nat Commun (2017) ncbi
domestic rabbit 多克隆
  • reverse phase protein lysate microarray; 人类; 图 st6
赛信通(上海)生物试剂有限公司 TSC1抗体(CST, 4906)被用于被用于reverse phase protein lysate microarray在人类样本上 (图 st6). Cancer Cell (2017) ncbi
domestic rabbit 多克隆
  • 免疫印迹基因敲除验证; 小鼠; 图 1a
赛信通(上海)生物试剂有限公司 TSC1抗体(Cell Signaling, 4906)被用于被用于免疫印迹基因敲除验证在小鼠样本上 (图 1a). EMBO J (2017) ncbi
domestic rabbit 单克隆(D43E2)
  • 免疫印迹; 小鼠; 图 1d
赛信通(上海)生物试剂有限公司 TSC1抗体(Cell Signaling, 6935)被用于被用于免疫印迹在小鼠样本上 (图 1d). Hum Mol Genet (2017) ncbi
domestic rabbit 多克隆
  • 免疫印迹; 人类; 图 1a
赛信通(上海)生物试剂有限公司 TSC1抗体(cell signalling, 4906)被用于被用于免疫印迹在人类样本上 (图 1a). J Clin Invest (2017) ncbi
domestic rabbit 单克隆(D43E2)
  • 免疫印迹基因敲除验证; 小鼠; 图 2b
赛信通(上海)生物试剂有限公司 TSC1抗体(Cell Signaling, 6935)被用于被用于免疫印迹基因敲除验证在小鼠样本上 (图 2b). Oncogene (2017) ncbi
domestic rabbit 多克隆
  • 免疫印迹; 小鼠; 图 6
赛信通(上海)生物试剂有限公司 TSC1抗体(Cell Signaling, 4906)被用于被用于免疫印迹在小鼠样本上 (图 6). Hepatology (2016) ncbi
domestic rabbit 多克隆
  • 免疫细胞化学; 人类; 1:200; 图 s7c
  • 免疫印迹; 人类; 1:1000; 图 s9a
  • 免疫细胞化学基因敲除验证; 小鼠; 1:200; 图 s7a
赛信通(上海)生物试剂有限公司 TSC1抗体(Cell Signaling, 4906)被用于被用于免疫细胞化学在人类样本上浓度为1:200 (图 s7c), 被用于免疫印迹在人类样本上浓度为1:1000 (图 s9a) 和 被用于免疫细胞化学基因敲除验证在小鼠样本上浓度为1:200 (图 s7a). Nat Commun (2016) ncbi
domestic rabbit 多克隆
  • 免疫印迹; 人类; 1:1000; 图 2e
赛信通(上海)生物试剂有限公司 TSC1抗体(Cell Signaling Technologies, 4906)被用于被用于免疫印迹在人类样本上浓度为1:1000 (图 2e). elife (2016) ncbi
domestic rabbit 单克隆(D43E2)
  • 免疫印迹; 人类; 图 1
赛信通(上海)生物试剂有限公司 TSC1抗体(Cell Signaling Tech, 6935s)被用于被用于免疫印迹在人类样本上 (图 1). Int J Mol Med (2015) ncbi
domestic rabbit 单克隆(D43E2)
  • 免疫印迹; 大鼠
赛信通(上海)生物试剂有限公司 TSC1抗体(Cell Signaling, 6935)被用于被用于免疫印迹在大鼠样本上. Mol Cell Biol (2015) ncbi
文章列表
  1. Schr xf6 tter S, Yuskaitis C, MacArthur M, Mitchell S, Hosios A, Osipovich M, et al. The non-essential TSC complex component TBC1D7 restricts tissue mTORC1 signaling and brain and neuron growth. Cell Rep. 2022;39:110824 pubmed 出版商
  2. Han H, Kim S, Kim Y, Jang S, Kwon Y, Choi D, et al. A novel role of CRTC2 in promoting nonalcoholic fatty liver disease. Mol Metab. 2022;55:101402 pubmed 出版商
  3. Chen X, Miao M, Zhou M, Chen J, Li D, Zhang L, et al. Poly-L-arginine promotes asthma angiogenesis through induction of FGFBP1 in airway epithelial cells via activation of the mTORC1-STAT3 pathway. Cell Death Dis. 2021;12:761 pubmed 出版商
  4. Alesi N, Akl E, Khabibullin D, Liu H, Nidhiry A, Garner E, et al. TSC2 regulates lysosome biogenesis via a non-canonical RAGC and TFEB-dependent mechanism. Nat Commun. 2021;12:4245 pubmed 出版商
  5. Zhang T, He M, Zhao L, Qin S, Zhu Z, Du X, et al. HDAC6 regulates primordial follicle activation through mTOR signaling pathway. Cell Death Dis. 2021;12:559 pubmed 出版商
  6. Zhang S, Li L, Xie D, Reddy S, Sleasman J, Ma L, et al. Regulation of Intrinsic and Bystander T Follicular Helper Cell Differentiation and Autoimmunity by Tsc1. Front Immunol. 2021;12:620437 pubmed 出版商
  7. Zhang Y, Swanda R, Nie L, Liu X, Wang C, Lee H, et al. mTORC1 couples cyst(e)ine availability with GPX4 protein synthesis and ferroptosis regulation. Nat Commun. 2021;12:1589 pubmed 出版商
  8. Jewell J, Fu V, Hong A, Yu F, Meng D, Melick C, et al. GPCR signaling inhibits mTORC1 via PKA phosphorylation of Raptor. elife. 2019;8: pubmed 出版商
  9. Mukhopadhyay U, Chanda S, Patra U, Mukherjee A, Rana S, Mukherjee A, et al. Synchronized Orchestration of miR-99b and let-7g Positively Regulates Rotavirus Infection by Modulating Autophagy. Sci Rep. 2019;9:1318 pubmed 出版商
  10. Poulopoulos A, Murphy A, Ozkan A, Davis P, Hatch J, Kirchner R, et al. Subcellular transcriptomes and proteomes of developing axon projections in the cerebral cortex. Nature. 2019;565:356-360 pubmed 出版商
  11. Hartleben G, Muller C, Kramer A, Schimmel H, Zidek L, Dornblut C, et al. Tuberous sclerosis complex is required for tumor maintenance in MYC-driven Burkitt's lymphoma. EMBO J. 2018;37: pubmed 出版商
  12. Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed 出版商
  13. Li H, Ren Y, Mao K, Hua F, Yang Y, Wei N, et al. FTO is involved in Alzheimer's disease by targeting TSC1-mTOR-Tau signaling. Biochem Biophys Res Commun. 2018;498:234-239 pubmed 出版商
  14. Zou J, Zhang B, Gutmann D, Wong M. Postnatal reduction of tuberous sclerosis complex 1 expression in astrocytes and neurons causes seizures in an age-dependent manner. Epilepsia. 2017;58:2053-2063 pubmed 出版商
  15. Bakula D, Müller A, Zuleger T, Takacs Z, Franz Wachtel M, Thost A, et al. WIPI3 and WIPI4 β-propellers are scaffolds for LKB1-AMPK-TSC signalling circuits in the control of autophagy. Nat Commun. 2017;8:15637 pubmed 出版商
  16. Cherniack A, Shen H, Walter V, Stewart C, Murray B, Bowlby R, et al. Integrated Molecular Characterization of Uterine Carcinosarcoma. Cancer Cell. 2017;31:411-423 pubmed 出版商
  17. Barilari M, Bonfils G, Treins C, Koka V, De Villeneuve D, Fabrega S, et al. ZRF1 is a novel S6 kinase substrate that drives the senescence programme. EMBO J. 2017;36:736-750 pubmed 出版商
  18. Jin F, Jiang K, Ji S, Wang L, Ni Z, Huang F, et al. Deficient TSC1/TSC2-complex suppression of SOX9-osteopontin-AKT signalling cascade constrains tumour growth in tuberous sclerosis complex. Hum Mol Genet. 2017;26:407-419 pubmed 出版商
  19. Cao J, Tyburczy M, Moss J, Darling T, Widlund H, Kwiatkowski D. Tuberous sclerosis complex inactivation disrupts melanogenesis via mTORC1 activation. J Clin Invest. 2017;127:349-364 pubmed 出版商
  20. Chen R, Duan J, Li L, Ma Q, Sun Q, Ma J, et al. mTOR promotes pituitary tumor development through activation of PTTG1. Oncogene. 2017;36:979-988 pubmed 出版商
  21. Jiang M, Liu L, He X, Wang H, Lin W, Wang H, et al. Regulation of PERK-eIF2? signalling by tuberous sclerosis complex-1 controls homoeostasis and survival of myelinating oligodendrocytes. Nat Commun. 2016;7:12185 pubmed 出版商
  22. Gong Q, Hu Z, Zhang F, Cui A, Chen X, Jiang H, et al. Fibroblast growth factor 21 improves hepatic insulin sensitivity by inhibiting mammalian target of rapamycin complex 1 in mice. Hepatology. 2016;64:425-38 pubmed 出版商
  23. Demetriades C, Plescher M, Teleman A. Lysosomal recruitment of TSC2 is a universal response to cellular stress. Nat Commun. 2016;7:10662 pubmed 出版商
  24. Carroll B, Maetzel D, Maddocks O, Otten G, Ratcliff M, Smith G, et al. Control of TSC2-Rheb signaling axis by arginine regulates mTORC1 activity. elife. 2016;5: pubmed 出版商
  25. Zhao J, Zhao D, Poage G, Mazumdar A, Zhang Y, Hill J, et al. Death-associated protein kinase 1 promotes growth of p53-mutant cancers. J Clin Invest. 2015;125:2707-20 pubmed 出版商
  26. Li L, Qi L, Liang Z, Song W, Liu Y, Wang Y, et al. Transforming growth factor-β1 induces EMT by the transactivation of epidermal growth factor signaling through HA/CD44 in lung and breast cancer cells. Int J Mol Med. 2015;36:113-22 pubmed 出版商
  27. Valianou M, Cox A, Pichette B, Hartley S, Paladhi U, Astrinidis A. Pharmacological inhibition of Polo-like kinase 1 (PLK1) by BI-2536 decreases the viability and survival of hamartin and tuberin deficient cells via induction of apoptosis and attenuation of autophagy. Cell Cycle. 2015;14:399-407 pubmed 出版商
  28. Ma X, Liu H, Murphy J, Foyil S, Godar R, Abuirqeba H, et al. Regulation of the transcription factor EB-PGC1α axis by beclin-1 controls mitochondrial quality and cardiomyocyte death under stress. Mol Cell Biol. 2015;35:956-76 pubmed 出版商
  29. Liang N, Zhang C, Dill P, Panasyuk G, Pion D, Koka V, et al. Regulation of YAP by mTOR and autophagy reveals a therapeutic target of tuberous sclerosis complex. J Exp Med. 2014;211:2249-63 pubmed 出版商
  30. Yen C, Lin Y, Yen C, Tsai H, Tsai T, Chang K, et al. Hepatitis B virus X protein upregulates mTOR signaling through IKKβ to increase cell proliferation and VEGF production in hepatocellular carcinoma. PLoS ONE. 2012;7:e41931 pubmed 出版商
  31. Kume K, Iizumi Y, Shimada M, Ito Y, Kishi T, Yamaguchi Y, et al. Role of N-end rule ubiquitin ligases UBR1 and UBR2 in regulating the leucine-mTOR signaling pathway. Genes Cells. 2010;15:339-49 pubmed 出版商
  32. Kuo H, Lee D, Chen C, Liu M, Chou C, Lee H, et al. ARD1 stabilization of TSC2 suppresses tumorigenesis through the mTOR signaling pathway. Sci Signal. 2010;3:ra9 pubmed 出版商
  33. Hartman T, Liu D, Zilfou J, Robb V, Morrison T, Watnick T, et al. The tuberous sclerosis proteins regulate formation of the primary cilium via a rapamycin-insensitive and polycystin 1-independent pathway. Hum Mol Genet. 2009;18:151-63 pubmed 出版商
  34. Boer K, Troost D, Jansen F, Nellist M, van den Ouweland A, Geurts J, et al. Clinicopathological and immunohistochemical findings in an autopsy case of tuberous sclerosis complex. Neuropathology. 2008;28:577-90 pubmed 出版商
  35. Lee D, Kuo H, Chen C, Hsu J, Chou C, Wei Y, et al. IKK beta suppression of TSC1 links inflammation and tumor angiogenesis via the mTOR pathway. Cell. 2007;130:440-55 pubmed