Xu M, Ge C, Qin Y, Lou D, Li Q, Feng J, et al. Functional loss of inactive rhomboid-like protein 2 mitigates obesity by suppressing pro-inflammatory macrophage activation-triggered adipose inflammation. Mol Metab. 2020;34:112-123 pubmed 出版商

Rodriguez Gil J, Watkins Chow D, Baxter L, Elliot G, Harper U, Wincovitch S, et al. Genetic background modifies phenotypic severity and longevity in a mouse model of Niemann-Pick disease type C1. Dis Model Mech. 2020;13: pubmed 出版商

Findlay A, McKie L, Keighren M, Clementson Mobbs S, Sanchez Pulido L, Wells S, et al. Fam151b, the mouse homologue of C.elegans menorin gene, is essential for retinal function. Sci Rep. 2020;10:437 pubmed 出版商

Thomson B, Carota I, Souma T, Soman S, Vestweber D, Quaggin S. Targeting the vascular-specific phosphatase PTPRB protects against retinal ganglion cell loss in a pre-clinical model of glaucoma. elife. 2019;8: pubmed 出版商

Gao Q, Zhu H, Dong L, Shi W, Chen R, Song Z, et al. Integrated Proteogenomic Characterization of HBV-Related Hepatocellular Carcinoma. Cell. 2019;179:561-577.e22 pubmed 出版商

Li L, Yan S, Zhang H, Zhang M, Huang G, Chen M. Interaction of hnRNP K with MAP 1B-LC1 promotes TGF-β1-mediated epithelial to mesenchymal transition in lung cancer cells. BMC Cancer. 2019;19:894 pubmed 出版商

Chatzifrangkeskou M, Pefani D, Eyres M, Vendrell I, Fischer R, Panková D, et al. RASSF1A is required for the maintenance of nuclear actin levels. EMBO J. 2019;38:e101168 pubmed 出版商

Kang Y, Torrente L, Falzone A, Elkins C, Liu M, Asara J, et al. Cysteine dioxygenase 1 is a metabolic liability for non-small cell lung cancer. elife. 2019;8: pubmed 出版商

Douanne T, André Grégoire G, Thys A, Trillet K, Gavard J, Bidere N. CYLD Regulates Centriolar Satellites Proteostasis by Counteracting the E3 Ligase MIB1. Cell Rep. 2019;27:1657-1665.e4 pubmed 出版商

Eckert M, Coscia F, Chryplewicz A, Chang J, Hernandez K, Pan S, et al. Proteomics reveals NNMT as a master metabolic regulator of cancer-associated fibroblasts. Nature. 2019;: pubmed 出版商

Lodge E, Santambrogio A, Russell J, Xekouki P, Jacques T, Johnson R, et al. Homeostatic and tumourigenic activity of SOX2+ pituitary stem cells is controlled by the LATS/YAP/TAZ cascade. elife. 2019;8: pubmed 出版商

Zhou N, Gutierrez Uzquiza A, Zheng X, Chang R, Vogl D, Garfall A, et al. RUNX proteins desensitize multiple myeloma to lenalidomide via protecting IKZFs from degradation. Leukemia. 2019;: pubmed 出版商

Melamed Z, López Erauskin J, Baughn M, Zhang O, Drenner K, Sun Y, et al. Premature polyadenylation-mediated loss of stathmin-2 is a hallmark of TDP-43-dependent neurodegeneration. Nat Neurosci. 2019;22:180-190 pubmed 出版商

Sachs N, Papaspyropoulos A, Zomer van Ommen D, Heo I, Böttinger L, Klay D, et al. Long-term expanding human airway organoids for disease modeling. EMBO J. 2019;38: pubmed 出版商

Mantri C, St John A. Immune synapses between mast cells and γδ T cells limit viral infection. J Clin Invest. 2019;129:1094-1108 pubmed 出版商

Meisenberg C, Pinder S, Hopkins S, Wooller S, Benstead Hume G, Pearl F, et al. Repression of Transcription at DNA Breaks Requires Cohesin throughout Interphase and Prevents Genome Instability. Mol Cell. 2019;73:212-223.e7 pubmed 出版商

Bigenzahn J, Collu G, Kartnig F, Pieraks M, Vladimer G, Heinz L, et al. LZTR1 is a regulator of RAS ubiquitination and signaling. Science. 2018;362:1171-1177 pubmed 出版商

Deissler H, Lang G, Lang G. Fate of the Fc fusion protein aflibercept in retinal endothelial cells: competition of recycling and degradation. Graefes Arch Clin Exp Ophthalmol. 2019;257:83-94 pubmed 出版商

Li W, Yue F, Dai Y, Shi B, Xu G, Jiang X, et al. Suppressor of hepatocellular carcinoma RASSF1A activates autophagy initiation and maturation. Cell Death Differ. 2018;: pubmed 出版商

Neubauer H, Tea M, Zebol J, Gliddon B, Stefanidis C, Moretti P, et al. Cytoplasmic dynein regulates the subcellular localization of sphingosine kinase 2 to elicit tumor-suppressive functions in glioblastoma. Oncogene. 2019;38:1151-1165 pubmed 出版商

Komori H, Goto Y, Kurayoshi K, Ozono E, Iwanaga R, Bradford A, et al. Differential requirement for dimerization partner DP between E2F-dependent activation of tumor suppressor and growth-related genes. Sci Rep. 2018;8:8438 pubmed 出版商

Liu H, Lorenzini P, Zhang F, Xu S, Wong M, Zheng J, et al. Alternative splicing analysis in human monocytes and macrophages reveals MBNL1 as major regulator. Nucleic Acids Res. 2018;46:6069-6086 pubmed 出版商

Manalo A, Schroer A, Fenix A, Shancer Z, Coogan J, Brolsma T, et al. Loss of CENP-F Results in Dilated Cardiomyopathy with Severe Disruption of Cardiac Myocyte Architecture. Sci Rep. 2018;8:7546 pubmed 出版商

Fregni G, Quinodoz M, Möller E, Vuille J, Galland S, Fusco C, et al. Reciprocal modulation of mesenchymal stem cells and tumor cells promotes lung cancer metastasis. EBioMedicine. 2018;29:128-145 pubmed 出版商

Spanos C, Maldonado E, Fisher C, Leenutaphong P, Oviedo Orta E, Windridge D, et al. Proteomic identification and characterization of hepatic glyoxalase 1 dysregulation in non-alcoholic fatty liver disease. Proteome Sci. 2018;16:4 pubmed 出版商

Yu R, Longo J, van Leeuwen J, Mullen P, Ba Alawi W, Haibe Kains B, et al. Statin-Induced Cancer Cell Death Can Be Mechanistically Uncoupled from Prenylation of RAS Family Proteins. Cancer Res. 2018;78:1347-1357 pubmed 出版商

Connell M, Chen H, Jiang J, Kuan C, Fotovati A, Chu T, et al. HMMR acts in the PLK1-dependent spindle positioning pathway and supports neural development. elife. 2017;6: pubmed 出版商

Shin J, Choi D, Sohn K, Kim J, Im M, Lee Y, et al. Targeted deletion of Crif1 in mouse epidermis impairs skin homeostasis and hair morphogenesis. Sci Rep. 2017;7:44828 pubmed 出版商

Miles A, Burr S, Grice G, Nathan J. The vacuolar-ATPase complex and assembly factors, TMEM199 and CCDC115, control HIF1? prolyl hydroxylation by regulating cellular iron levels. elife. 2017;6: pubmed 出版商

van Riel W, Rai A, Bianchi S, Katrukha E, Liu Q, Heck A, et al. Kinesin-4 KIF21B is a potent microtubule pausing factor. elife. 2017;6: pubmed 出版商

Katoh Y, Michisaka S, Nozaki S, Funabashi T, Hirano T, Takei R, et al. Practical method for targeted disruption of cilia-related genes by using CRISPR/Cas9-mediated, homology-independent knock-in system. Mol Biol Cell. 2017;28:898-906 pubmed 出版商

Beauchemin H, Shooshtarizadeh P, Vadnais C, Vassen L, Pastore Y, Moroy T. Gfi1b controls integrin signaling-dependent cytoskeleton dynamics and organization in megakaryocytes. Haematologica. 2017;102:484-497 pubmed 出版商

Jin M, Pomp O, Shinoda T, Toba S, Torisawa T, Furuta K, et al. Katanin p80, NuMA and cytoplasmic dynein cooperate to control microtubule dynamics. Sci Rep. 2017;7:39902 pubmed 出版商

Sterling J, Guttha S, Song Y, Song D, Hadziahmetovic M, Dunaief J. Iron importers Zip8 and Zip14 are expressed in retina and regulated by retinal iron levels. Exp Eye Res. 2017;155:15-23 pubmed 出版商

van de Ven R, de Groot J, Park D, van Domselaar R, de Jong D, Szuhai K, et al. p120-catenin prevents multinucleation through control of MKLP1-dependent RhoA activity during cytokinesis. Nat Commun. 2016;7:13874 pubmed 出版商

Artemenko Y, Axiotakis L, Borleis J, Iglesias P, Devreotes P. Chemical and mechanical stimuli act on common signal transduction and cytoskeletal networks. Proc Natl Acad Sci U S A. 2016;113:E7500-E7509 pubmed

Fang Y, Kong Y, Xi J, Zhu M, Zhu T, Jiang T, et al. Preclinical activity of MBM-5 in gastrointestinal cancer by inhibiting NEK2 kinase activity. Oncotarget. 2016;7:79327-79341 pubmed 出版商

Vanhoutte D, Schips T, Kwong J, Davis J, Tjondrokoesoemo A, Brody M, et al. Thrombospondin expression in myofibers stabilizes muscle membranes. elife. 2016;5: pubmed 出版商

Hortemo K, Lunde P, Anonsen J, Kvaløy H, Munkvik M, Rehn T, et al. Exercise training increases protein O-GlcNAcylation in rat skeletal muscle. Physiol Rep. 2016;4: pubmed

Justa Schuch D, Silva Garcia M, Pilla E, Engelke M, Kilisch M, Lenz C, et al. DPP9 is a novel component of the N-end rule pathway targeting the tyrosine kinase Syk. elife. 2016;5: pubmed 出版商

Chen R, Wang S, Zhang Y, Hou R, Jiang J, Cui H. CD147 promotes cell motility via upregulation of p190-B RhoGAP in hepatocellular carcinoma. Cancer Cell Int. 2016;16:69 pubmed 出版商

Xiaojun W, Yan L, Hong X, Xianghong Z, Shifeng L, Dingjie X, et al. Acetylated ?-Tubulin Regulated by N-Acetyl-Seryl-Aspartyl-Lysyl-Proline(Ac-SDKP) Exerts the Anti-fibrotic Effect in Rat Lung Fibrosis Induced by Silica. Sci Rep. 2016;6:32257 pubmed 出版商

Balboula A, Nguyen A, Gentilello A, Quartuccio S, Drutovic D, Solc P, et al. Haspin kinase regulates microtubule-organizing center clustering and stability through Aurora kinase C in mouse oocytes. J Cell Sci. 2016;129:3648-3660 pubmed

Liu Q, Liu F, Yu K, Tas R, Grigoriev I, Remmelzwaal S, et al. MICAL3 Flavoprotein Monooxygenase Forms a Complex with Centralspindlin and Regulates Cytokinesis. J Biol Chem. 2016;291:20617-29 pubmed 出版商

Rasmussen M, Lyskjær I, Jersie Christensen R, Tarpgaard L, Primdal Bengtson B, Nielsen M, et al. miR-625-3p regulates oxaliplatin resistance by targeting MAP2K6-p38 signalling in human colorectal adenocarcinoma cells. Nat Commun. 2016;7:12436 pubmed 出版商

Vogan J, Zhang X, Youmans D, Regalado S, Johnson J, Hockemeyer D, et al. Minimized human telomerase maintains telomeres and resolves endogenous roles of H/ACA proteins, TCAB1, and Cajal bodies. elife. 2016;5: pubmed 出版商

Batalha V, Ferreira D, Coelho J, Valadas J, Gomes R, Temido Ferreira M, et al. The caffeine-binding adenosine A2A receptor induces age-like HPA-axis dysfunction by targeting glucocorticoid receptor function. Sci Rep. 2016;6:31493 pubmed 出版商

Ding Y, Li X, Xia G, Ren H, Zhou X, Su B, et al. ProBDNF inhibits collective migration and chemotaxis of rat Schwann cells. Tissue Cell. 2016;48:503-10 pubmed 出版商

Zhou A, Lin K, Zhang S, Chen Y, Zhang N, Xue J, et al. Nuclear GSK3β promotes tumorigenesis by phosphorylating KDM1A and inducing its deubiquitylation by USP22. Nat Cell Biol. 2016;18:954-966 pubmed 出版商

El Sikhry H, Alsaleh N, Dakarapu R, Falck J, Seubert J. Novel Roles of Epoxyeicosanoids in Regulating Cardiac Mitochondria. PLoS ONE. 2016;11:e0160380 pubmed 出版商

Furukawa Y, Tanemura K, Igarashi K, Ideta Otsuka M, Aisaki K, Kitajima S, et al. Learning and Memory Deficits in Male Adult Mice Treated with a Benzodiazepine Sleep-Inducing Drug during the Juvenile Period. Front Neurosci. 2016;10:339 pubmed 出版商

Bernabé Rubio M, Andrés G, Casares Arias J, Fernández Barrera J, Rangel L, Reglero Real N, et al. Novel role for the midbody in primary ciliogenesis by polarized epithelial cells. J Cell Biol. 2016;214:259-73 pubmed 出版商

Ku T, Swaney J, Park J, Albanese A, Murray E, Cho J, et al. Multiplexed and scalable super-resolution imaging of three-dimensional protein localization in size-adjustable tissues. Nat Biotechnol. 2016;34:973-81 pubmed 出版商

Gao Y, Lui W, Lee W, Cheng C. Polarity protein Crumbs homolog-3 (CRB3) regulates ectoplasmic specialization dynamics through its action on F-actin organization in Sertoli cells. Sci Rep. 2016;6:28589 pubmed 出版商

Müller A, Giambruno R, Weißer J, Májek P, Hofer A, Bigenzahn J, et al. Identifying Kinase Substrates via a Heavy ATP Kinase Assay and Quantitative Mass Spectrometry. Sci Rep. 2016;6:28107 pubmed 出版商

Grainger D, Kutzler L, Rannels S, Kimball S. Validation of a commercially available anti-REDD1 antibody using RNA interference and REDD1-/- mouse embryonic fibroblasts. F1000Res. 2016;5:250 pubmed 出版商

Cunningham D, Parajuli K, Zhang C, Wang G, Mei J, Zhang Q, et al. Monomethyl Auristatin E Phosphate Inhibits Human Prostate Cancer Growth. Prostate. 2016;76:1420-30 pubmed 出版商

Zhang W, Chin T, Yang H, Nga M, Lunny D, Lim E, et al. Tumour-initiating cell-specific miR-1246 and miR-1290 expression converge to promote non-small cell lung cancer progression. Nat Commun. 2016;7:11702 pubmed 出版商

Meinhardt G, Saleh L, Otti G, Haider S, Velicky P, Fiala C, et al. Wingless ligand 5a is a critical regulator of placental growth and survival. Sci Rep. 2016;6:28127 pubmed 出版商

Gómez Sánchez R, Yakhine Diop S, Bravo San Pedro J, Pizarro Estrella E, Rodríguez Arribas M, Climent V, et al. PINK1 deficiency enhances autophagy and mitophagy induction. Mol Cell Oncol. 2016;3:e1046579 pubmed 出版商

Nakagawa Y, Oikawa F, Mizuno S, Ohno H, Yagishita Y, Satoh A, et al. Hyperlipidemia and hepatitis in liver-specific CREB3L3 knockout mice generated using a one-step CRISPR/Cas9 system. Sci Rep. 2016;6:27857 pubmed 出版商

Penterling C, Drexler G, Böhland C, Stamp R, Wilke C, Braselmann H, et al. Depletion of Histone Demethylase Jarid1A Resulting in Histone Hyperacetylation and Radiation Sensitivity Does Not Affect DNA Double-Strand Break Repair. PLoS ONE. 2016;11:e0156599 pubmed 出版商

Mukhopadhyay A, Sehgal L, Bose A, Gulvady A, Senapati P, Thorat R, et al. 14-3-3? Prevents Centrosome Amplification and Neoplastic Progression. Sci Rep. 2016;6:26580 pubmed 出版商

Xi Z, Yao M, Li Y, Xie C, Holst J, Liu T, et al. Guttiferone K impedes cell cycle re-entry of quiescent prostate cancer cells via stabilization of FBXW7 and subsequent c-MYC degradation. Cell Death Dis. 2016;7:e2252 pubmed 出版商

Singh V, Singh M, Gorantla S, Poluektova L, Maggirwar S. Smoothened Agonist Reduces Human Immunodeficiency Virus Type-1-Induced Blood-Brain Barrier Breakdown in Humanized Mice. Sci Rep. 2016;6:26876 pubmed 出版商

Sundararaman A, Amirtham U, Rangarajan A. Calcium-Oxidant Signaling Network Regulates AMP-activated Protein Kinase (AMPK) Activation upon Matrix Deprivation. J Biol Chem. 2016;291:14410-29 pubmed 出版商

Elias I, Ferre T, Vilà L, Munoz S, Casellas A, Garcia M, et al. ALOX5AP Overexpression in Adipose Tissue Leads to LXA4 Production and Protection Against Diet-Induced Obesity and Insulin Resistance. Diabetes. 2016;65:2139-50 pubmed 出版商

Rao S, Flores Rodriguez N, Page S, Wong C, Robinson P, Chircop M. The Clathrin-dependent Spindle Proteome. Mol Cell Proteomics. 2016;15:2537-53 pubmed 出版商

Kwon O, Kim K, Lee E, Kim M, Choi S, Li H, et al. Induction of MiR-21 by Stereotactic Body Radiotherapy Contributes to the Pulmonary Fibrotic Response. PLoS ONE. 2016;11:e0154942 pubmed 出版商

Yen H, Liu Y, Kan C, Wei H, Lee S, Wei Y, et al. Disruption of the human COQ5-containing protein complex is associated with diminished coenzyme Q10 levels under two different conditions of mitochondrial energy deficiency. Biochim Biophys Acta. 2016;1860:1864-76 pubmed 出版商

Dai Y, Hung L, Chen R, Lai C, Chang K. ON 01910.Na inhibits growth of diffuse large B-cell lymphoma by cytoplasmic sequestration of sumoylated C-MYB/TRAF6 complex. Transl Res. 2016;175:129-143.e13 pubmed 出版商

Watanabe Y, Papoutsoglou P, Maturi V, Tsubakihara Y, Hottiger M, Heldin C, et al. Regulation of Bone Morphogenetic Protein Signaling by ADP-ribosylation. J Biol Chem. 2016;291:12706-23 pubmed 出版商

Matias A, Manieri T, Cerchiaro G. Zinc Chelation Mediates the Lysosomal Disruption without Intracellular ROS Generation. Oxid Med Cell Longev. 2016;2016:6724585 pubmed 出版商

Noda K, Kitami M, Kitami K, Kaku M, Komatsu Y. Canonical and noncanonical intraflagellar transport regulates craniofacial skeletal development. Proc Natl Acad Sci U S A. 2016;113:E2589-97 pubmed 出版商

Li R, Jin Z, Gao L, Liu P, Yang Z, Zhang D. Effective protein inhibition in intact mouse oocytes through peptide nanoparticle-mediated antibody transfection. Peerj. 2016;4:e1849 pubmed 出版商

Jung A, Stoiber C, Herkt C, Schulz C, Bertrams W, Schmeck B. Legionella pneumophila-Derived Outer Membrane Vesicles Promote Bacterial Replication in Macrophages. PLoS Pathog. 2016;12:e1005592 pubmed 出版商

Kushner E, Ferro L, Yu Z, Bautch V. Excess centrosomes perturb dynamic endothelial cell repolarization during blood vessel formation. Mol Biol Cell. 2016;27:1911-20 pubmed 出版商

Lai C, Tsai C, Kuo W, Ho T, Day C, Pai P, et al. Multi-Strain Probiotics Inhibit Cardiac Myopathies and Autophagy to Prevent Heart Injury in High-Fat Diet-Fed Rats. Int J Med Sci. 2016;13:277-85 pubmed 出版商

Pinz S, Unser S, Rascle A. Signal transducer and activator of transcription STAT5 is recruited to c-Myc super-enhancer. BMC Mol Biol. 2016;17:10 pubmed 出版商

Conway A, Van Nostrand E, Pratt G, Aigner S, Wilbert M, Sundararaman B, et al. Enhanced CLIP Uncovers IMP Protein-RNA Targets in Human Pluripotent Stem Cells Important for Cell Adhesion and Survival. Cell Rep. 2016;15:666-679 pubmed 出版商

Lee J, Kuo C, Tsai S, Cheng S, Chen S, Chan H, et al. Inhibition of HDAC3- and HDAC6-Promoted Survivin Expression Plays an Important Role in SAHA-Induced Autophagy and Viability Reduction in Breast Cancer Cells. Front Pharmacol. 2016;7:81 pubmed 出版商

Chozinski T, Halpern A, Okawa H, Kim H, Tremel G, Wong R, et al. Expansion microscopy with conventional antibodies and fluorescent proteins. Nat Methods. 2016;13:485-8 pubmed 出版商

Chu C, Ossipova O, Ioannou A, Sokol S. Prickle3 synergizes with Wtip to regulate basal body organization and cilia growth. Sci Rep. 2016;6:24104 pubmed 出版商

Thakur B, Dasgupta N, Ta A, Das S. Physiological TLR5 expression in the intestine is regulated by differential DNA binding of Sp1/Sp3 through simultaneous Sp1 dephosphorylation and Sp3 phosphorylation by two different PKC isoforms. Nucleic Acids Res. 2016;44:5658-72 pubmed 出版商

Prieto J, León M, Ponsoda X, Sendra R, Bort R, Ferrer Lorente R, et al. Early ERK1/2 activation promotes DRP1-dependent mitochondrial fission necessary for cell reprogramming. Nat Commun. 2016;7:11124 pubmed 出版商

Vincent A, Berthel E, Dacheux E, Magnard C, Venezia N. BRCA1 affects protein phosphatase 6 signalling through its interaction with ANKRD28. Biochem J. 2016;473:949-60 pubmed 出版商

Stritt S, Nurden P, Favier R, Favier M, Ferioli S, Gotru S, et al. Defects in TRPM7 channel function deregulate thrombopoiesis through altered cellular Mg(2+) homeostasis and cytoskeletal architecture. Nat Commun. 2016;7:11097 pubmed 出版商

Xing Y, Sun W, Wang Y, Gao F, Ma H. Mutual inhibition of insulin signaling and PHLPP-1 determines cardioprotective efficiency of Akt in aged heart. Aging (Albany NY). 2016;8:873-88 pubmed 出版商

Kimball S, Gordon B, Moyer J, Dennis M, Jefferson L. Leucine induced dephosphorylation of Sestrin2 promotes mTORC1 activation. Cell Signal. 2016;28:896-906 pubmed 出版商

Douanne T, Gavard J, Bidère N. The paracaspase MALT1 cleaves the LUBAC subunit HOIL1 during antigen receptor signaling. J Cell Sci. 2016;129:1775-80 pubmed 出版商

Pal K, Hwang S, Somatilaka B, Badgandi H, Jackson P, DeFea K, et al. Smoothened determines ?-arrestin-mediated removal of the G protein-coupled receptor Gpr161 from the primary cilium. J Cell Biol. 2016;212:861-75 pubmed 出版商

Müller M, Mönkemöller V, Hennig S, Hubner W, Huser T. Open-source image reconstruction of super-resolution structured illumination microscopy data in ImageJ. Nat Commun. 2016;7:10980 pubmed 出版商

Lee T, Liu C, Chang Y, Nieh S, Lin Y, Jao S, et al. Increased chemoresistance via Snail-Raf kinase inhibitor protein signaling in colorectal cancer in response to a nicotine derivative. Oncotarget. 2016;7:23512-20 pubmed 出版商

Obino D, Farina F, Malbec O, Sáez P, Maurin M, Gaillard J, et al. Actin nucleation at the centrosome controls lymphocyte polarity. Nat Commun. 2016;7:10969 pubmed 出版商

Gilormini M, Malesys C, Armandy E, Manas P, Guy J, Magne N, et al. Preferential targeting of cancer stem cells in the radiosensitizing effect of ABT-737 on HNSCC. Oncotarget. 2016;7:16731-44 pubmed 出版商

Seip K, Fleten K, Barkovskaya A, Nygaard V, Haugen M, Engesæter B, et al. Fibroblast-induced switching to the mesenchymal-like phenotype and PI3K/mTOR signaling protects melanoma cells from BRAF inhibitors. Oncotarget. 2016;7:19997-20015 pubmed 出版商

Eriksson J, Le Joncour V, Nummela P, Jahkola T, Virolainen S, Laakkonen P, et al. Gene expression analyses of primary melanomas reveal CTHRC1 as an important player in melanoma progression. Oncotarget. 2016;7:15065-92 pubmed 出版商

Marchildon F, Fu D, Lala Tabbert N, Wiper Bergeron N. CCAAT/enhancer binding protein beta protects muscle satellite cells from apoptosis after injury and in cancer cachexia. Cell Death Dis. 2016;7:e2109 pubmed 出版商

Kabat A, Harrison O, Riffelmacher T, Moghaddam A, Pearson C, Laing A, et al. The autophagy gene Atg16l1 differentially regulates Treg and TH2 cells to control intestinal inflammation. elife. 2016;5:e12444 pubmed 出版商

Hong J, Lee J, Chung I. Telomerase activates transcription of cyclin D1 gene through an interaction with NOL1. J Cell Sci. 2016;129:1566-79 pubmed 出版商

Chang H, Wu R, Shang M, Sato T, Chen C, Shapiro J, et al. Reduction in mitochondrial iron alleviates cardiac damage during injury. EMBO Mol Med. 2016;8:247-67 pubmed 出版商

Tang E, Lee W, Cheng C. Coordination of Actin- and Microtubule-Based Cytoskeletons Supports Transport of Spermatids and Residual Bodies/Phagosomes During Spermatogenesis in the Rat Testis. Endocrinology. 2016;157:1644-59 pubmed 出版商

Fu Z, Wang L, Cui H, Peng J, Wang S, Geng J, et al. A novel small-molecule compound targeting CD147 inhibits the motility and invasion of hepatocellular carcinoma cells. Oncotarget. 2016;7:9429-47 pubmed 出版商

Chojnacka K, Bilinska B, Mruk D. Interleukin 1alpha-induced disruption of the Sertoli cell cytoskeleton affects gap junctional communication. Cell Signal. 2016;28:469-480 pubmed 出版商

Wen B, Li S, Li H, Chen Y, Ma X, Wang J, et al. Microphthalmia-associated transcription factor regulates the visual cycle genes Rlbp1 and Rdh5 in the retinal pigment epithelium. Sci Rep. 2016;6:21208 pubmed 出版商

Czub B, Shah A, Alfano G, Kruczek P, Chakarova C, Bhattacharya S. TOPORS, a Dual E3 Ubiquitin and Sumo1 Ligase, Interacts with 26 S Protease Regulatory Subunit 4, Encoded by the PSMC1 Gene. PLoS ONE. 2016;11:e0148678 pubmed 出版商

Singhal G, Fisher F, Chee M, Tan T, El Ouaamari A, Adams A, et al. Fibroblast Growth Factor 21 (FGF21) Protects against High Fat Diet Induced Inflammation and Islet Hyperplasia in Pancreas. PLoS ONE. 2016;11:e0148252 pubmed 出版商

Bleckmann A, Conradi L, Menck K, Schmick N, Schubert A, Rietkötter E, et al. β-catenin-independent WNT signaling and Ki67 in contrast to the estrogen receptor status are prognostic and associated with poor prognosis in breast cancer liver metastases. Clin Exp Metastasis. 2016;33:309-23 pubmed 出版商

Divisato G, Formicola D, Esposito T, Merlotti D, Pazzaglia L, Del Fattore A, et al. ZNF687 Mutations in Severe Paget Disease of Bone Associated with Giant Cell Tumor. Am J Hum Genet. 2016;98:275-86 pubmed 出版商

Di Magno L, Basile A, Coni S, Manni S, Sdruscia G, D Amico D, et al. The energy sensor AMPK regulates Hedgehog signaling in human cells through a unique Gli1 metabolic checkpoint. Oncotarget. 2016;7:9538-49 pubmed 出版商

Walter M, Teissandier A, Pérez Palacios R, Bourc his D. An epigenetic switch ensures transposon repression upon dynamic loss of DNA methylation in embryonic stem cells. elife. 2016;5: pubmed 出版商

Moudry P, Watanabe K, Wolanin K, Bartkova J, Wassing I, Watanabe S, et al. TOPBP1 regulates RAD51 phosphorylation and chromatin loading and determines PARP inhibitor sensitivity. J Cell Biol. 2016;212:281-8 pubmed 出版商

Goulielmaki M, Koustas E, Moysidou E, Vlassi M, Sasazuki T, Shirasawa S, et al. BRAF associated autophagy exploitation: BRAF and autophagy inhibitors synergise to efficiently overcome resistance of BRAF mutant colorectal cancer cells. Oncotarget. 2016;7:9188-221 pubmed 出版商

Jayachandran P, Olmo V, Sanchez S, McFarland R, Vital E, Werner J, et al. Microtubule-associated protein 1b is required for shaping the neural tube. Neural Dev. 2016;11:1 pubmed 出版商

Soo Lee N, Jin Chung H, Kim H, Yun Lee S, Ji J, Seo Y, et al. TRAIP/RNF206 is required for recruitment of RAP80 to sites of DNA damage. Nat Commun. 2016;7:10463 pubmed 出版商

M L, P P, T K, M P, E S, J P, et al. Essential role of HDAC6 in the regulation of PD-L1 in melanoma. Mol Oncol. 2016;10:735-750 pubmed 出版商

Kitamura A, Nakayama Y, Shibasaki A, Taki A, Yuno S, Takeda K, et al. Interaction of RNA with a C-terminal fragment of the amyotrophic lateral sclerosis-associated TDP43 reduces cytotoxicity. Sci Rep. 2016;6:19230 pubmed 出版商

Vivar O, Masi G, Carpier J, Magalhaes J, Galgano D, Pazour G, et al. IFT20 controls LAT recruitment to the immune synapse and T-cell activation in vivo. Proc Natl Acad Sci U S A. 2016;113:386-91 pubmed 出版商

Cawthorn W, Scheller E, Parlee S, Pham H, Learman B, Redshaw C, et al. Expansion of Bone Marrow Adipose Tissue During Caloric Restriction Is Associated With Increased Circulating Glucocorticoids and Not With Hypoleptinemia. Endocrinology. 2016;157:508-21 pubmed 出版商

Sakamoto A, Akiyama Y, Shimada S, Zhu W, Yuasa Y, Tanaka S. DNA Methylation in the Exon 1 Region and Complex Regulation of Twist1 Expression in Gastric Cancer Cells. PLoS ONE. 2015;10:e0145630 pubmed 出版商

Huang R, Langdon S, Tse M, Mullen P, Um I, Faratian D, et al. The role of HDAC2 in chromatin remodelling and response to chemotherapy in ovarian cancer. Oncotarget. 2016;7:4695-711 pubmed 出版商

Brunati M, Perucca S, Han L, Cattaneo A, Consolato F, Andolfo A, et al. The serine protease hepsin mediates urinary secretion and polymerisation of Zona Pellucida domain protein uromodulin. elife. 2015;4:e08887 pubmed 出版商

Duffy D, Krstic A, Halasz M, Schwarzl T, Fey D, Iljin K, et al. Integrative omics reveals MYCN as a global suppressor of cellular signalling and enables network-based therapeutic target discovery in neuroblastoma. Oncotarget. 2015;6:43182-201 pubmed 出版商

Loiselle J, Tessier S, Sutherland L. Post-transcriptional regulation of Rbm5 expression in undifferentiated H9c2 myoblasts. In Vitro Cell Dev Biol Anim. 2016;52:327-36 pubmed 出版商

Verdone L, La Fortezza M, Ciccarone F, Caiafa P, Zampieri M, Caserta M. Poly(ADP-Ribosyl)ation Affects Histone Acetylation and Transcription. PLoS ONE. 2015;10:e0144287 pubmed 出版商

Mehraein Ghomi F, Church D, Schreiber C, Weichmann A, Basu H, Wilding G. Inhibitor of p52 NF-κB subunit and androgen receptor (AR) interaction reduces growth of human prostate cancer cells by abrogating nuclear translocation of p52 and phosphorylated AR(ser81). Genes Cancer. 2015;6:428-44 pubmed

Kim M, Kim M, Park S, Lee C, Lim D. Role of Angiomotin-like 2 mono-ubiquitination on YAP inhibition. EMBO Rep. 2016;17:64-78 pubmed 出版商

Liwak Muir U, Dobson C, Naing T, Wylie Q, Chehade L, Baird S, et al. ERK8 is a novel HuR kinase that regulates tumour suppressor PDCD4 through a miR-21 dependent mechanism. Oncotarget. 2016;7:1439-50 pubmed 出版商

Chow C, Ebine K, Knab L, Bentrem D, Kumar K, Munshi H. Cancer Cell Invasion in Three-dimensional Collagen Is Regulated Differentially by Gα13 Protein and Discoidin Domain Receptor 1-Par3 Protein Signaling. J Biol Chem. 2016;291:1605-18 pubmed 出版商

Massouridès E, Polentes J, Mangeot P, Mournetas V, Nectoux J, Deburgrave N, et al. Dp412e: a novel human embryonic dystrophin isoform induced by BMP4 in early differentiated cells. Skelet Muscle. 2015;5:40 pubmed 出版商

Lee S, Won J, Yang J, Lee J, Kim S, Lee E, et al. AKAP6 inhibition impairs myoblast differentiation and muscle regeneration: Positive loop between AKAP6 and myogenin. Sci Rep. 2015;5:16523 pubmed 出版商

Sassa A, Kamoshita N, Kanemaru Y, Honma M, Yasui M. Xeroderma Pigmentosum Group A Suppresses Mutagenesis Caused by Clustered Oxidative DNA Adducts in the Human Genome. PLoS ONE. 2015;10:e0142218 pubmed 出版商

Lee J, Park K, Han D, Bang N, Kim D, Na H, et al. PharmDB-K: Integrated Bio-Pharmacological Network Database for Traditional Korean Medicine. PLoS ONE. 2015;10:e0142624 pubmed 出版商

Zhang L, Ward J, Cheng Z, Dernburg A. The auxin-inducible degradation (AID) system enables versatile conditional protein depletion in C. elegans. Development. 2015;142:4374-84 pubmed 出版商

Sun S, Shi G, Sha H, Ji Y, Han X, Shu X, et al. IRE1α is an endogenous substrate of endoplasmic-reticulum-associated degradation. Nat Cell Biol. 2015;17:1546-55 pubmed 出版商

Seidel C, Schnekenburger M, Mazumder A, Teiten M, Kirsch G, Dicato M, et al. 4-Hydroxybenzoic acid derivatives as HDAC6-specific inhibitors modulating microtubular structure and HSP90α chaperone activity against prostate cancer. Biochem Pharmacol. 2016;99:31-52 pubmed 出版商

Waddell D, Duffin P, Haddock A, Triplett V, Saredy J, Kakareka K, et al. Isolation, expression analysis and characterization of NEFA-interacting nuclear protein 30 and RING finger and SPRY domain containing 1 in skeletal muscle. Gene. 2016;576:319-32 pubmed 出版商

Habiger C, Jäger G, Walter M, Iftner T, Stubenrauch F. Interferon Kappa Inhibits Human Papillomavirus 31 Transcription by Inducing Sp100 Proteins. J Virol. 2016;90:694-704 pubmed 出版商

Lin K, Kao S, Lai C, Chen C, Wu C, Hsu H, et al. Tumor Suppressor Lzap Suppresses Wnt/β-Catenin Signaling to Promote Zebrafish Embryonic Ventral Cell Fates via the Suppression of Inhibitory Phosphorylation of Glycogen Synthase Kinase 3. J Biol Chem. 2015;290:29808-19 pubmed 出版商

Ragot A, Pietropaolo S, Vincent J, Delage P, Zhang H, Allinquant B, et al. Genetic deletion of the Histone Deacetylase 6 exacerbates selected behavioral deficits in the R6/1 mouse model for Huntington's disease. Brain Behav. 2015;5:e00361 pubmed 出版商

Nakakido M, Deng Z, Suzuki T, Dohmae N, Nakamura Y, Hamamoto R. PRMT6 increases cytoplasmic localization of p21CDKN1A in cancer cells through arginine methylation and makes more resistant to cytotoxic agents. Oncotarget. 2015;6:30957-67 pubmed 出版商

Ambroise G, Portier A, Roders N, Arnoult D, Vazquez A. Subcellular localization of PUMA regulates its pro-apoptotic activity in Burkitt's lymphoma B cells. Oncotarget. 2015;6:38181-94 pubmed 出版商

Bruurs L, Donker L, Zwakenberg S, Zwartkruis F, Begthel H, Knisely A, et al. ATP8B1-mediated spatial organization of Cdc42 signaling maintains singularity during enterocyte polarization. J Cell Biol. 2015;210:1055-63 pubmed 出版商

Yao M, Xie C, Kiang M, Teng Y, Harman D, Tiffen J, et al. Targeting of cytosolic phospholipase A2α impedes cell cycle re-entry of quiescent prostate cancer cells. Oncotarget. 2015;6:34458-74 pubmed 出版商

Asghar A, Lajeunesse A, Dulla K, Combes G, Thebault P, Nigg E, et al. Bub1 autophosphorylation feeds back to regulate kinetochore docking and promote localized substrate phosphorylation. Nat Commun. 2015;6:8364 pubmed 出版商

Bollu L, Katreddy R, Blessing A, Pham N, Zheng B, Wu X, et al. Intracellular activation of EGFR by fatty acid synthase dependent palmitoylation. Oncotarget. 2015;6:34992-5003 pubmed 出版商

Machado Neto J, de Melo Campos P, Favaro P, Lazarini M, da Silva Santos Duarte A, Lorand Metze I, et al. Stathmin 1 inhibition amplifies ruxolitinib-induced apoptosis in JAK2V617F cells. Oncotarget. 2015;6:29573-84 pubmed 出版商

Mansara P, Deshpande R, Vaidya M, Kaul Ghanekar R. Differential Ratios of Omega Fatty Acids (AA/EPA+DHA) Modulate Growth, Lipid Peroxidation and Expression of Tumor Regulatory MARBPs in Breast Cancer Cell Lines MCF7 and MDA-MB-231. PLoS ONE. 2015;10:e0136542 pubmed 出版商

Wong P, Feng Y, Wang J, Shi R, Jiang X. Regulation of autophagy by coordinated action of mTORC1 and protein phosphatase 2A. Nat Commun. 2015;6:8048 pubmed 出版商

Stockley J, Markert E, Zhou Y, Robson C, Elliott D, Lindberg J, et al. The RNA-binding protein Sam68 regulates expression and transcription function of the androgen receptor splice variant AR-V7. Sci Rep. 2015;5:13426 pubmed 出版商

Wolter S, Kloth C, Golombek M, Dittmar F, Försterling L, Seifert R. cCMP causes caspase-dependent apoptosis in mouse lymphoma cell lines. Biochem Pharmacol. 2015;98:119-31 pubmed 出版商

Sakabe I, Hu R, Jin L, Clarke R, Kasid U. TMEM33: a new stress-inducible endoplasmic reticulum transmembrane protein and modulator of the unfolded protein response signaling. Breast Cancer Res Treat. 2015;153:285-97 pubmed 出版商

Lee H, Park Y, Cho M, Chae S, Yoo Y, Kwon M, et al. The chromatin remodeller RSF1 is essential for PLK1 deposition and function at mitotic kinetochores. Nat Commun. 2015;6:7904 pubmed 出版商

Ma Q, Hu Q, Xu R, Zhen X, Wang G. Protease Omi facilitates neurite outgrowth in mouse neuroblastoma N2a cells by cleaving transcription factor E2F1. Acta Pharmacol Sin. 2015;36:966-75 pubmed 出版商

Hamazaki J, Hirayama S, Murata S. Redundant Roles of Rpn10 and Rpn13 in Recognition of Ubiquitinated Proteins and Cellular Homeostasis. PLoS Genet. 2015;11:e1005401 pubmed 出版商

Lee K, Im J, Shibata E, Park J, Handa N, Kowalczykowski S, et al. MCM8-9 complex promotes resection of double-strand break ends by MRE11-RAD50-NBS1 complex. Nat Commun. 2015;6:7744 pubmed 出版商

Succoio M, Comegna M, D Ambrosio C, Scaloni A, Cimino F, Faraonio R. Proteomic analysis reveals novel common genes modulated in both replicative and stress-induced senescence. J Proteomics. 2015;128:18-29 pubmed 出版商

Fink E, Mannava S, Bagati A, Bianchi Smiraglia A, Nair J, Moparthy K, et al. Mitochondrial thioredoxin reductase regulates major cytotoxicity pathways of proteasome inhibitors in multiple myeloma cells. Leukemia. 2016;30:104-11 pubmed 出版商

Schipany K, Rosner M, Ionce L, Hengstschläger M, Kovacic B. eIF3 controls cell size independently of S6K1-activity. Oncotarget. 2015;6:24361-75 pubmed

Nagaoka K, Matoba T, Mao Y, Nakano Y, Ikeda G, Egusa S, et al. A New Therapeutic Modality for Acute Myocardial Infarction: Nanoparticle-Mediated Delivery of Pitavastatin Induces Cardioprotection from Ischemia-Reperfusion Injury via Activation of PI3K/Akt Pathway and Anti-Inflammation in a Rat Model. PLoS ONE. 2015;10:e0132451 pubmed 出版商

Lee J, Lee Y, Lim J, Byun H, Park I, Kim G, et al. Mitochondrial Respiratory Dysfunction Induces Claudin-1 Expression via Reactive Oxygen Species-mediated Heat Shock Factor 1 Activation, Leading to Hepatoma Cell Invasiveness. J Biol Chem. 2015;290:21421-31 pubmed 出版商

Andersson L, Scharin Täng M, Lundqvist A, Lindbom M, Mardani I, Fogelstrand P, et al. Rip2 modifies VEGF-induced signalling and vascular permeability in myocardial ischaemia. Cardiovasc Res. 2015;107:478-86 pubmed 出版商

Graffe M, Zenisek D, Taraska J. A marginal band of microtubules transports and organizes mitochondria in retinal bipolar synaptic terminals. J Gen Physiol. 2015;146:109-17 pubmed 出版商

Duan H, Li Y, Lim H, Wang W. Identification of 5-nitrofuran-2-amide derivatives that induce apoptosis in triple negative breast cancer cells by activating C/EBP-homologous protein expression. Bioorg Med Chem. 2015;23:4514-21 pubmed 出版商

Riz I, Hawley T, Hawley R. KLF4-SQSTM1/p62-associated prosurvival autophagy contributes to carfilzomib resistance in multiple myeloma models. Oncotarget. 2015;6:14814-31 pubmed

Condelli V, Maddalena F, Sisinni L, Lettini G, Matassa D, Piscazzi A, et al. Targeting TRAP1 as a downstream effector of BRAF cytoprotective pathway: a novel strategy for human BRAF-driven colorectal carcinoma. Oncotarget. 2015;6:22298-309 pubmed

Kiebala M, Singh M, Piepenbrink M, Qiu X, Kobie J, Maggirwar S. Platelet Activation in Human Immunodeficiency Virus Type-1 Patients Is Not Altered with Cocaine Abuse. PLoS ONE. 2015;10:e0130061 pubmed 出版商

Petroni M, Sardina F, Heil C, Sahún Roncero M, Colicchia V, Veschi V, et al. The MRN complex is transcriptionally regulated by MYCN during neural cell proliferation to control replication stress. Cell Death Differ. 2016;23:197-206 pubmed 出版商

Bock F, Tanzer M, Haschka M, Krumschnabel G, Sohm B, Goetsch K, et al. The p53 binding protein PDCD5 is not rate-limiting in DNA damage induced cell death. Sci Rep. 2015;5:11268 pubmed 出版商

Neo S, Itahana Y, Alagu J, Kitagawa M, Guo A, Lee S, et al. TRIM28 Is an E3 Ligase for ARF-Mediated NPM1/B23 SUMOylation That Represses Centrosome Amplification. Mol Cell Biol. 2015;35:2851-63 pubmed 出版商

García Cano J, Ambroise G, Pascual Serra R, Carrión M, Serrano Oviedo L, Ortega Muelas M, et al. Exploiting the potential of autophagy in cisplatin therapy: A new strategy to overcome resistance. Oncotarget. 2015;6:15551-65 pubmed

Koenig J, Werdehausen R, Linley J, Habib A, Vernon J, Lolignier S, et al. Regulation of Nav1.7: A Conserved SCN9A Natural Antisense Transcript Expressed in Dorsal Root Ganglia. PLoS ONE. 2015;10:e0128830 pubmed 出版商

Nagata T, Yasukawa H, Kyogoku S, Oba T, Takahashi J, Nohara S, et al. Cardiac-Specific SOCS3 Deletion Prevents In Vivo Myocardial Ischemia Reperfusion Injury through Sustained Activation of Cardioprotective Signaling Molecules. PLoS ONE. 2015;10:e0127942 pubmed 出版商

O Callaghan K, Palagano E, Butini S, Campiani G, Williams D, Zisterer D, et al. Induction of apoptosis in oral squamous carcinoma cells by pyrrolo-1,5-benzoxazepines. Mol Med Rep. 2015;12:3748-3754 pubmed 出版商

Cicchini C, de Nonno V, Battistelli C, Cozzolino A, De Santis Puzzonia M, Ciafrè S, et al. Epigenetic control of EMT/MET dynamics: HNF4α impacts DNMT3s through miRs-29. Biochim Biophys Acta. 2015;1849:919-29 pubmed 出版商

Fauster A, Rebsamen M, Huber K, Bigenzahn J, Stukalov A, Lardeau C, et al. A cellular screen identifies ponatinib and pazopanib as inhibitors of necroptosis. Cell Death Dis. 2015;6:e1767 pubmed 出版商

Bhatt D, Puig K, Gorr M, Wold L, Combs C. A pilot study to assess effects of long-term inhalation of airborne particulate matter on early Alzheimer-like changes in the mouse brain. PLoS ONE. 2015;10:e0127102 pubmed 出版商

Reales E, Bernabé Rubio M, Casares Arias J, Rentero C, Fernández Barrera J, Rangel L, et al. The MAL protein is crucial for proper membrane condensation at the ciliary base, which is required for primary cilium elongation. J Cell Sci. 2015;128:2261-70 pubmed 出版商

Li W, Zhang C, Ren A, Li T, Jin R, Li G, et al. Shikonin Suppresses Skin Carcinogenesis via Inhibiting Cell Proliferation. PLoS ONE. 2015;10:e0126459 pubmed 出版商

Piskareva O, Harvey H, Nolan J, Conlon R, Alcock L, Buckley P, et al. The development of cisplatin resistance in neuroblastoma is accompanied by epithelial to mesenchymal transition in vitro. Cancer Lett. 2015;364:142-55 pubmed 出版商

Woan K, Lienlaf M, Perez Villaroel P, Lee C, Cheng F, Knox T, et al. Targeting histone deacetylase 6 mediates a dual anti-melanoma effect: Enhanced antitumor immunity and impaired cell proliferation. Mol Oncol. 2015;9:1447-1457 pubmed 出版商

Mahale S, Bharate S, Manda S, Joshi P, Jenkins P, Vishwakarma R, et al. Antitumour potential of BPT: a dual inhibitor of cdk4 and tubulin polymerization. Cell Death Dis. 2015;6:e1743 pubmed 出版商

Barrett K, Fang H, Cukovic D, Dombkowski A, Kocarek T, Runge Morris M. Upregulation of UGT2B4 Expression by 3'-Phosphoadenosine-5'-Phosphosulfate Synthase Knockdown: Implications for Coordinated Control of Bile Acid Conjugation. Drug Metab Dispos. 2015;43:1061-70 pubmed 出版商

Mauro Lizcano M, Esteban Martínez L, Seco E, Serrano Puebla A, García Ledo L, Figueiredo Pereira C, et al. New method to assess mitophagy flux by flow cytometry. Autophagy. 2015;11:833-43 pubmed 出版商

Ratovitski E. Phospho-ΔNp63α-responsive microRNAs contribute to the regulation of necroptosis in squamous cell carcinoma upon cisplatin exposure. FEBS Lett. 2015;589:1352-8 pubmed 出版商

Cruz Bermúdez A, Vallejo C, Vicente Blanco R, Gallardo M, Fernández Moreno M, Quintanilla M, et al. Enhanced tumorigenicity by mitochondrial DNA mild mutations. Oncotarget. 2015;6:13628-43 pubmed

Jang D, Kwon H, Jeong K, Lee J, Pak Y. Essential role of flotillin-1 palmitoylation in the intracellular localization and signaling function of IGF-1 receptor. J Cell Sci. 2015;128:2179-90 pubmed 出版商

Min K, Liggett J, Silva G, Wu W, Wang R, Shen R, et al. NAG-1/GDF15 accumulates in the nucleus and modulates transcriptional regulation of the Smad pathway. Oncogene. 2016;35:377-88 pubmed 出版商

Chong L, Hsu Y, Lee T, Lin Y, Chiu Y, Yang K, et al. Fluvastatin attenuates hepatic steatosis-induced fibrogenesis in rats through inhibiting paracrine effect of hepatocyte on hepatic stellate cells. BMC Gastroenterol. 2015;15:22 pubmed 出版商

Chung J, Bauer D, Ghamari A, Nizzi C, Deck K, Kingsley P, et al. The mTORC1/4E-BP pathway coordinates hemoglobin production with L-leucine availability. Sci Signal. 2015;8:ra34 pubmed 出版商

Wang W, Huang X, Xin H, Fu M, Xue A, Wu Z. TRAF Family Member-associated NF-κB Activator (TANK) Inhibits Genotoxic Nuclear Factor κB Activation by Facilitating Deubiquitinase USP10-dependent Deubiquitination of TRAF6 Ligase. J Biol Chem. 2015;290:13372-85 pubmed 出版商

Yi J, Zhang X, Huan X, Song S, Wang W, Tian Q, et al. Dual targeting of microtubule and topoisomerase II by α-carboline derivative YCH337 for tumor proliferation and growth inhibition. Oncotarget. 2015;6:8960-73 pubmed

Mertz T, Sharma S, Chabes A, Shcherbakova P. Colon cancer-associated mutator DNA polymerase δ variant causes expansion of dNTP pools increasing its own infidelity. Proc Natl Acad Sci U S A. 2015;112:E2467-76 pubmed 出版商

Shi Y, Chen J, Karner C, Long F. Hedgehog signaling activates a positive feedback mechanism involving insulin-like growth factors to induce osteoblast differentiation. Proc Natl Acad Sci U S A. 2015;112:4678-83 pubmed 出版商

Zhang Q, Kuang H, Chen C, Yan J, Do Umehara H, Liu X, et al. The kinase Jnk2 promotes stress-induced mitophagy by targeting the small mitochondrial form of the tumor suppressor ARF for degradation. Nat Immunol. 2015;16:458-66 pubmed 出版商

Muramatsu R, Kuroda M, Matoba K, Lin H, Takahashi C, Koyama Y, et al. Prostacyclin prevents pericyte loss and demyelination induced by lysophosphatidylcholine in the central nervous system. J Biol Chem. 2015;290:11515-25 pubmed 出版商

Yanagi T, Shi R, Aza Blanc P, Reed J, Matsuzawa S. PCTAIRE1-knockdown sensitizes cancer cells to TNF family cytokines. PLoS ONE. 2015;10:e0119404 pubmed 出版商

Balboula A, Stein P, Schultz R, Schindler K. RBBP4 regulates histone deacetylation and bipolar spindle assembly during oocyte maturation in the mouse. Biol Reprod. 2015;92:105 pubmed 出版商

Conn S, Pillman K, Toubia J, Conn V, Salmanidis M, Phillips C, et al. The RNA binding protein quaking regulates formation of circRNAs. Cell. 2015;160:1125-34 pubmed 出版商

Rappa G, Green T, Karbanová J, Corbeil D, Lorico A. Tetraspanin CD9 determines invasiveness and tumorigenicity of human breast cancer cells. Oncotarget. 2015;6:7970-91 pubmed

Eriksen A, Torgersen M, Holm K, Abrahamsen G, Spurkland A, Moskaug J, et al. Retinoic acid-induced IgG production in TLR-activated human primary B cells involves ULK1-mediated autophagy. Autophagy. 2015;11:460-71 pubmed 出版商

Grabner B, Schramek D, Mueller K, Moll H, Svinka J, Hoffmann T, et al. Disruption of STAT3 signalling promotes KRAS-induced lung tumorigenesis. Nat Commun. 2015;6:6285 pubmed 出版商

Park S, Jeong J, Park Y, Park K, Lee H, Lee N, et al. Disrupted-in-schizophrenia-1 (DISC1) Regulates Endoplasmic Reticulum Calcium Dynamics. Sci Rep. 2015;5:8694 pubmed 出版商

Zolfaghari P, Carré J, Parker N, Curtin N, Duchen M, Singer M. Skeletal muscle dysfunction is associated with derangements in mitochondrial bioenergetics (but not UCP3) in a rodent model of sepsis. Am J Physiol Endocrinol Metab. 2015;308:E713-25 pubmed 出版商

Hortemo K, Aronsen J, Lunde I, Sjaastad I, Lunde P, Sejersted O. Exhausting treadmill running causes dephosphorylation of sMLC2 and reduced level of myofilament MLCK2 in slow twitch rat soleus muscle. Physiol Rep. 2015;3: pubmed 出版商

Kushwaha D, O Leary C, Cron K, Deraska P, Zhu K, D Andrea A, et al. USP9X inhibition promotes radiation-induced apoptosis in non-small cell lung cancer cells expressing mid-to-high MCL1. Cancer Biol Ther. 2015;16:392-401 pubmed 出版商

Pollack D, Xiao Y, Shrivasatava V, Levy A, Andrusier M, D ARMIENTO J, et al. CDK14 expression is down-regulated by cigarette smoke in vivo and in vitro. Toxicol Lett. 2015;234:120-30 pubmed 出版商

Hirunsai M, Srikuea R, Yimlamai T. Heat stress promotes extracellular matrix remodelling via TGF-β1 and MMP-2/TIMP-2 modulation in tenotomised soleus and plantaris muscles. Int J Hyperthermia. 2015;31:336-48 pubmed 出版商

Miyake S, Muramatsu R, Hamaguchi M, Yamashita T. Prolyl hydroxylase regulates axonal rewiring and motor recovery after traumatic brain injury. Cell Death Dis. 2015;6:e1638 pubmed 出版商

Kwon H, Lee J, Jeong K, Jang D, Pak Y. Fatty acylated caveolin-2 is a substrate of insulin receptor tyrosine kinase for insulin receptor substrate-1-directed signaling activation. Biochim Biophys Acta. 2015;1853:1022-34 pubmed 出版商

Bailey J, Fields A, Cheng K, Lee A, Wagenaar E, Lagrois R, et al. WD repeat-containing protein 5 (WDR5) localizes to the midbody and regulates abscission. J Biol Chem. 2015;290:8987-9001 pubmed 出版商

Raghunandan M, Chaudhury I, Kelich S, Hanenberg H, Sobeck A. FANCD2, FANCJ and BRCA2 cooperate to promote replication fork recovery independently of the Fanconi Anemia core complex. Cell Cycle. 2015;14:342-53 pubmed 出版商

Jeong H, Gil N, Lee H, Cho S, Kim K, Chun K, et al. Timely Degradation of Wip1 Phosphatase by APC/C Activator Protein Cdh1 is Necessary for Normal Mitotic Progression. J Cell Biochem. 2015;116:1602-12 pubmed 出版商

Xue J, Chen Y, Wu Y, Wang Z, Zhou A, Zhang S, et al. Tumour suppressor TRIM33 targets nuclear β-catenin degradation. Nat Commun. 2015;6:6156 pubmed 出版商

Kawasaki Y, Ishigami S, Arigami T, Uenosono Y, Yanagita S, Uchikado Y, et al. Clinicopathological significance of nuclear factor (erythroid-2)-related factor 2 (Nrf2) expression in gastric cancer. BMC Cancer. 2015;15:5 pubmed 出版商

Kopanic J, Schlingmann B, Koval M, Lau A, Sorgen P, Su V. Degradation of gap junction connexins is regulated by the interaction with Cx43-interacting protein of 75 kDa (CIP75). Biochem J. 2015;466:571-85 pubmed 出版商

Al Gubory K, Arianmanesh M, Garrel C, Fowler P. The conceptus regulates tryptophanyl-tRNA synthetase and superoxide dismutase 2 in the sheep caruncular endometrium during early pregnancy. Int J Biochem Cell Biol. 2015;60:112-8 pubmed 出版商

Rizkallah R, Batsomboon P, Dudley G, Hurt M. Identification of the oncogenic kinase TOPK/PBK as a master mitotic regulator of C2H2 zinc finger proteins. Oncotarget. 2015;6:1446-61 pubmed

Gao Z, Zhang J, Henagan T, Lee J, Ye X, Wang H, et al. P65 inactivation in adipocytes and macrophages attenuates adipose inflammatory response in lean but not in obese mice. Am J Physiol Endocrinol Metab. 2015;308:E496-505 pubmed 出版商

Karner C, Esen E, Okunade A, Patterson B, Long F. Increased glutamine catabolism mediates bone anabolism in response to WNT signaling. J Clin Invest. 2015;125:551-62 pubmed 出版商

Rebsamen M, Pochini L, Stasyk T, de Araújo M, Galluccio M, Kandasamy R, et al. SLC38A9 is a component of the lysosomal amino acid sensing machinery that controls mTORC1. Nature. 2015;519:477-81 pubmed 出版商

Earley L, Kawano Y, Adachi K, Sun X, Dai M, Nakai H. Identification and characterization of nuclear and nucleolar localization signals in the adeno-associated virus serotype 2 assembly-activating protein. J Virol. 2015;89:3038-48 pubmed 出版商

Toropainen S, Malinen M, Kaikkonen S, Rytinki M, Jääskeläinen T, Sahu B, et al. SUMO ligase PIAS1 functions as a target gene selective androgen receptor coregulator on prostate cancer cell chromatin. Nucleic Acids Res. 2015;43:848-61 pubmed 出版商

Sasaki M, Yoshimura Miyakoshi M, Sato Y, Nakanuma Y. A possible involvement of endoplasmic reticulum stress in biliary epithelial autophagy and senescence in primary biliary cirrhosis. J Gastroenterol. 2015;50:984-95 pubmed 出版商

Van de Laar E, Clifford M, Hasenoeder S, Kim B, Wang D, Lee S, et al. Cell surface marker profiling of human tracheal basal cells reveals distinct subpopulations, identifies MST1/MSP as a mitogenic signal, and identifies new biomarkers for lung squamous cell carcinomas. Respir Res. 2014;15:160 pubmed 出版商

Toda T, Ishida K, Kiyama H, Yamashita T, Lee S. Down-regulation of KCC2 expression and phosphorylation in motoneurons, and increases the number of in primary afferent projections to motoneurons in mice with post-stroke spasticity. PLoS ONE. 2014;9:e114328 pubmed 出版商

Hong A, Lee J, Chung K. Ubiquitin-specific protease 22 (USP22) positively regulates RCAN1 protein levels through RCAN1 de-ubiquitination. J Cell Physiol. 2015;230:1651-60 pubmed 出版商

Gonzalez Granado J, Navarro Puche A, Molina Sánchez P, Blanco Berrocal M, Viana R, Font de Mora J, et al. Sorting nexin 6 enhances lamin a synthesis and incorporation into the nuclear envelope. PLoS ONE. 2014;9:e115571 pubmed 出版商

Machado Neto J, Lazarini M, Favaro P, de Melo Campos P, Scopim Ribeiro R, Franchi Junior G, et al. ANKHD1 silencing inhibits Stathmin 1 activity, cell proliferation and migration of leukemia cells. Biochim Biophys Acta. 2015;1853:583-93 pubmed 出版商

Menck K, Scharf C, Bleckmann A, Dyck L, Rost U, Wenzel D, et al. Tumor-derived microvesicles mediate human breast cancer invasion through differentially glycosylated EMMPRIN. J Mol Cell Biol. 2015;7:143-53 pubmed 出版商

Bollu L, Ren J, Blessing A, Katreddy R, Gao G, Xu L, et al. Involvement of de novo synthesized palmitate and mitochondrial EGFR in EGF induced mitochondrial fusion of cancer cells. Cell Cycle. 2014;13:2415-30 pubmed 出版商

Tang E, Mok K, Lee W, Cheng C. EB1 regulates tubulin and actin cytoskeletal networks at the sertoli cell blood-testis barrier in male rats: an in vitro study. Endocrinology. 2015;156:680-93 pubmed 出版商

Kim T, Kim H, Kang Y, Yoon S, Lee J, Choi W, et al. Psammaplin A induces Sirtuin 1-dependent autophagic cell death in doxorubicin-resistant MCF-7/adr human breast cancer cells and xenografts. Biochim Biophys Acta. 2015;1850:401-10 pubmed 出版商

Wang S, Cui H, Liu Y, Zhao P, Zhang Y, Fu Z, et al. CD147 promotes Src-dependent activation of Rac1 signaling through STAT3/DOCK8 during the motility of hepatocellular carcinoma cells. Oncotarget. 2015;6:243-57 pubmed

Liu F, Shen W, Qiu H, Hu X, Zhang C, Chu T. Prostate cancer cells induce osteoblastic differentiation via semaphorin 3A. Prostate. 2015;75:370-80 pubmed 出版商

Lee K, Yeo S, Sung C, Kim S. Twist1 is a key regulator of cancer-associated fibroblasts. Cancer Res. 2015;75:73-85 pubmed 出版商

Kong S, Thiruppathi M, Qiu Q, Lin Z, Dong H, Chini E, et al. DBC1 is a suppressor of B cell activation by negatively regulating alternative NF-κB transcriptional activity. J Immunol. 2014;193:5515-24 pubmed 出版商

Olmsted Z, Colliver A, Riehlman T, Paluh J. Kinesin-14 and kinesin-5 antagonistically regulate microtubule nucleation by γ-TuRC in yeast and human cells. Nat Commun. 2014;5:5339 pubmed 出版商

Hock A, Vigneron A, Vousden K. Ubiquitin-specific peptidase 42 (USP42) functions to deubiquitylate histones and regulate transcriptional activity. J Biol Chem. 2014;289:34862-70 pubmed 出版商

Díaz Chiguer D, Hernández Luis F, Nogueda Torres B, Castillo R, Reynoso Ducoing O, Hernández Campos A, et al. JVG9, a benzimidazole derivative, alters the surface and cytoskeleton of Trypanosoma cruzi bloodstream trypomastigotes. Mem Inst Oswaldo Cruz. 2014;109:757-60 pubmed

Cohen Kedar S, Baram L, Elad H, Brazowski E, Guzner Gur H, Dotan I. Human intestinal epithelial cells respond to β-glucans via Dectin-1 and Syk. Eur J Immunol. 2014;44:3729-40 pubmed 出版商

Patel D, Dubash A, Kreitzer G, Green K. Disease mutations in desmoplakin inhibit Cx43 membrane targeting mediated by desmoplakin-EB1 interactions. J Cell Biol. 2014;206:779-97 pubmed 出版商

Deng Z, Matsuda K, Tanikawa C, Lin J, Furukawa Y, Hamamoto R, et al. Late Cornified Envelope Group I, a novel target of p53, regulates PRMT5 activity. Neoplasia. 2014;16:656-64 pubmed 出版商

De Nicola F, Catena V, Rinaldo C, Bruno T, Iezzi S, Sorino C, et al. HIPK2 sustains apoptotic response by phosphorylating Che-1/AATF and promoting its degradation. Cell Death Dis. 2014;5:e1414 pubmed 出版商

Ribeiro Varandas E, Pereira H, Monteiro S, Neves E, Brito L, Ferreira R, et al. Bisphenol A disrupts transcription and decreases viability in aging vascular endothelial cells. Int J Mol Sci. 2014;15:15791-805 pubmed 出版商

Zhao X, Zhu L, Chang Q, Jiang C, You Y, Luo T, et al. C-type lectin receptor dectin-3 mediates trehalose 6,6'-dimycolate (TDM)-induced Mincle expression through CARD9/Bcl10/MALT1-dependent nuclear factor (NF)-κB activation. J Biol Chem. 2014;289:30052-62 pubmed 出版商

Huang S, Lee C, Wang H, Chang Y, Lin C, Chen C, et al. 6-Dehydrogingerdione restrains lipopolysaccharide-induced inflammatory responses in RAW 264.7 macrophages. J Agric Food Chem. 2014;62:9171-9 pubmed 出版商

Strakova J, Dean J, Sharpe K, Meyers T, Odom G, Townsend D. Dystrobrevin increases dystrophin's binding to the dystrophin-glycoprotein complex and provides protection during cardiac stress. J Mol Cell Cardiol. 2014;76:106-15 pubmed 出版商

Ginet V, Pittet M, Rummel C, Osterheld M, Meuli R, Clarke P, et al. Dying neurons in thalamus of asphyxiated term newborns and rats are autophagic. Ann Neurol. 2014;76:695-711 pubmed 出版商

Sutinen P, Rahkama V, Rytinki M, Palvimo J. Nuclear mobility and activity of FOXA1 with androgen receptor are regulated by SUMOylation. Mol Endocrinol. 2014;28:1719-28 pubmed 出版商

Cheng F, Lienlaf M, Wang H, Perez Villarroel P, Lee C, Woan K, et al. A novel role for histone deacetylase 6 in the regulation of the tolerogenic STAT3/IL-10 pathway in APCs. J Immunol. 2014;193:2850-62 pubmed 出版商

Dutta B, Yan R, Lim S, Tam J, Sze S. Quantitative profiling of chromatome dynamics reveals a novel role for HP1BP3 in hypoxia-induced oncogenesis. Mol Cell Proteomics. 2014;13:3236-49 pubmed 出版商

de Souza E, Meirelles G, Godoy B, Perez A, Smetana J, Doxsey S, et al. Characterization of the human NEK7 interactome suggests catalytic and regulatory properties distinct from those of NEK6. J Proteome Res. 2014;13:4074-90 pubmed 出版商

Mostocotto C, Carbone M, Battistelli C, Ciotti A, Amati P, Maione R. Poly(ADP-ribosyl)ation is required to modulate chromatin changes at c-MYC promoter during emergence from quiescence. PLoS ONE. 2014;9:e102575 pubmed 出版商

Patel A, Burton D, Halvorsen K, Balkan W, Reiner T, Perez Stable C, et al. MutT Homolog 1 (MTH1) maintains multiple KRAS-driven pro-malignant pathways. Oncogene. 2015;34:2586-96 pubmed 出版商

Lo Sasso G, Ryu D, Mouchiroud L, Fernando S, Anderson C, Katsyuba E, et al. Loss of Sirt1 function improves intestinal anti-bacterial defense and protects from colitis-induced colorectal cancer. PLoS ONE. 2014;9:e102495 pubmed 出版商

Gaillard F, Kuny S, Sauve Y. Retinal distribution of Disabled-1 in a diurnal murine rodent, the Nile grass rat Arvicanthis niloticus. Exp Eye Res. 2014;125:236-43 pubmed 出版商

Ranjan R, Deng J, Chung S, Lee Y, Park G, Xiao L, et al. The transcription factor nuclear factor of activated T cells c3 modulates the function of macrophages in sepsis. J Innate Immun. 2014;6:754-64 pubmed 出版商

Pratt S, Shah S, Ward C, Kerr J, Stains J, Lovering R. Recovery of altered neuromuscular junction morphology and muscle function in mdx mice after injury. Cell Mol Life Sci. 2015;72:153-64 pubmed 出版商

Tao W, Leng X, Chakraborty S, Ma H, Arlinghaus R. c-Abl activates janus kinase 2 in normal hematopoietic cells. J Biol Chem. 2014;289:21463-72 pubmed 出版商

Liu Q, Boudot A, Ni J, Hennessey T, Beauparlant S, Rajabi H, et al. Cyclin D1 and C/EBP? LAP1 operate in a common pathway to promote mammary epithelial cell differentiation. Mol Cell Biol. 2014;34:3168-79 pubmed 出版商

Mannino M, Gomez Roman N, Hochegger H, Chalmers A. Differential sensitivity of Glioma stem cells to Aurora kinase A inhibitors: implications for stem cell mitosis and centrosome dynamics. Stem Cell Res. 2014;13:135-43 pubmed 出版商

Lee M, Moreno C, Saavedra H. E2F activators signal and maintain centrosome amplification in breast cancer cells. Mol Cell Biol. 2014;34:2581-99 pubmed

Mäki Jouppila J, Laine L, Rehnberg J, Narvi E, Tiikkainen P, Hukasova E, et al. Centmitor-1, a novel acridinyl-acetohydrazide, possesses similar molecular interaction field and antimitotic cellular phenotype as rigosertib, on 01910.Na. Mol Cancer Ther. 2014;13:1054-66 pubmed 出版商

Huszar J, Payne C. MIR146A inhibits JMJD3 expression and osteogenic differentiation in human mesenchymal stem cells. FEBS Lett. 2014;588:1850-6 pubmed 出版商

Erdozain A, Morentin B, Bedford L, King E, Tooth D, Brewer C, et al. Alcohol-related brain damage in humans. PLoS ONE. 2014;9:e93586 pubmed 出版商

Karpurapu M, Ranjan R, Deng J, Chung S, Lee Y, Xiao L, et al. Krüppel like factor 4 promoter undergoes active demethylation during monocyte/macrophage differentiation. PLoS ONE. 2014;9:e93362 pubmed 出版商

Castellani L, Root McCaig J, Frendo Cumbo S, Beaudoin M, Wright D. Exercise training protects against an acute inflammatory insult in mouse epididymal adipose tissue. J Appl Physiol (1985). 2014;116:1272-80 pubmed 出版商

Hashimoto Y, Shirane M, Matsuzaki F, Saita S, Ohnishi T, Nakayama K. Protrudin regulates endoplasmic reticulum morphology and function associated with the pathogenesis of hereditary spastic paraplegia. J Biol Chem. 2014;289:12946-61 pubmed 出版商

Jia J, Bosley A, Thompson A, Hoskins J, Cheuk A, Collins I, et al. CLPTM1L promotes growth and enhances aneuploidy in pancreatic cancer cells. Cancer Res. 2014;74:2785-95 pubmed 出版商

Cobbs C, Matlaf L, Harkins L. Methods for the detection of cytomegalovirus in glioblastoma cells and tissues. Methods Mol Biol. 2014;1119:165-96 pubmed 出版商

Gilan O, Diesch J, Amalia M, Jastrzebski K, Chueh A, Verrills N, et al. PR55?-containing protein phosphatase 2A complexes promote cancer cell migration and invasion through regulation of AP-1 transcriptional activity. Oncogene. 2015;34:1333-9 pubmed 出版商

Kakiuchi K, Tsuda A, Goto Y, Shimada T, Taniguchi K, Takagishi K, et al. Cell-surface DEAD-box polypeptide 4-immunoreactive cells and gonocytes are two distinct populations in postnatal porcine testes. Biol Reprod. 2014;90:82 pubmed 出版商

Uzer G, Pongkitwitoon S, Ian C, Thompson W, Rubin J, Chan M, et al. Gap junctional communication in osteocytes is amplified by low intensity vibrations in vitro. PLoS ONE. 2014;9:e90840 pubmed 出版商

Witsch T, Niess G, Sakkas E, Likhoshvay T, Becker S, Herold S, et al. Transglutaminase 2: a new player in bronchopulmonary dysplasia?. Eur Respir J. 2014;44:109-21 pubmed 出版商

Balboula A, Schindler K. Selective disruption of aurora C kinase reveals distinct functions from aurora B kinase during meiosis in mouse oocytes. PLoS Genet. 2014;10:e1004194 pubmed 出版商

Hwang W, Jiang J, Yang S, Huang T, Lan H, Teng H, et al. MicroRNA-146a directs the symmetric division of Snail-dominant colorectal cancer stem cells. Nat Cell Biol. 2014;16:268-80 pubmed 出版商

Yang B, Wagner J, Damaschke N, Yao T, Wuerzberger Davis S, Lee M, et al. A novel pathway links oxidative stress to loss of insulin growth factor-2 (IGF2) imprinting through NF-?B activation. PLoS ONE. 2014;9:e88052 pubmed 出版商

Liang Q, Dexheimer T, Zhang P, Rosenthal A, Villamil M, You C, et al. A selective USP1-UAF1 inhibitor links deubiquitination to DNA damage responses. Nat Chem Biol. 2014;10:298-304 pubmed 出版商

Nakajima W, Hicks M, Tanaka N, Krystal G, Harada H. Noxa determines localization and stability of MCL-1 and consequently ABT-737 sensitivity in small cell lung cancer. Cell Death Dis. 2014;5:e1052 pubmed 出版商

Pavet V, Shlyakhtina Y, He T, Ceschin D, Kohonen P, Perala M, et al. Plasminogen activator urokinase expression reveals TRAIL responsiveness and supports fractional survival of cancer cells. Cell Death Dis. 2014;5:e1043 pubmed 出版商

Vittori A, Breda C, Repici M, Orth M, Roos R, Outeiro T, et al. Copy-number variation of the neuronal glucose transporter gene SLC2A3 and age of onset in Huntington's disease. Hum Mol Genet. 2014;23:3129-37 pubmed 出版商

Arroyo A, Camoletto P, Morando L, Sassoè Pognetto M, Giustetto M, Van Veldhoven P, et al. Pharmacological reversion of sphingomyelin-induced dendritic spine anomalies in a Niemann Pick disease type A mouse model. EMBO Mol Med. 2014;6:398-413 pubmed 出版商

Vellaichamy E, Das S, Subramanian U, Maeda N, Pandey K. Genetically altered mutant mouse models of guanylyl cyclase/natriuretic peptide receptor-A exhibit the cardiac expression of proinflammatory mediators in a gene-dose-dependent manner. Endocrinology. 2014;155:1045-56 pubmed 出版商

Klinger M, Wang W, Kuhns S, Bärenz F, Dräger Meurer S, Pereira G, et al. The novel centriolar satellite protein SSX2IP targets Cep290 to the ciliary transition zone. Mol Biol Cell. 2014;25:495-507 pubmed 出版商

Shrivastava V, Marmor H, Chernyak S, Goldstein M, Feliciano M, Vigodner M. Cigarette smoke affects posttranslational modifications and inhibits capacitation-induced changes in human sperm proteins. Reprod Toxicol. 2014;43:125-9 pubmed 出版商

Sanchez Roman I, Gomez A, Naudi A, Jove M, Gomez J, Lopez Torres M, et al. Independent and additive effects of atenolol and methionine restriction on lowering rat heart mitochondria oxidative stress. J Bioenerg Biomembr. 2014;46:159-72 pubmed 出版商

Del Nagro C, Choi J, Xiao Y, Rangell L, Mohan S, Pandita A, et al. Chk1 inhibition in p53-deficient cell lines drives rapid chromosome fragmentation followed by caspase-independent cell death. Cell Cycle. 2014;13:303-14 pubmed 出版商

Loiselle J, Sutherland L. Differential downregulation of Rbm5 and Rbm10 during skeletal and cardiac differentiation. In Vitro Cell Dev Biol Anim. 2014;50:331-9 pubmed 出版商

Wilson V. Growth and differentiation of HaCaT keratinocytes. Methods Mol Biol. 2014;1195:33-41 pubmed 出版商

Chen Z, Morris D, Jiang L, Liu Y, Rui L. SH2B1 in ?-cells regulates glucose metabolism by promoting ?-cell survival and islet expansion. Diabetes. 2014;63:585-95 pubmed 出版商

Almenar Queralt A, Kim S, Benner C, Herrera C, Kang D, Garcia Bassets I, et al. Presenilins regulate neurotrypsin gene expression and neurotrypsin-dependent agrin cleavage via cyclic AMP response element-binding protein (CREB) modulation. J Biol Chem. 2013;288:35222-36 pubmed 出版商

Lee J, Park J, Kwon O, Kim H, Fornace A, Cha H. Off-target response of a Wip1 chemical inhibitor in skin keratinocytes. J Dermatol Sci. 2014;73:125-34 pubmed 出版商

DeGennaro C, Alver B, Marguerat S, Stepanova E, Davis C, Bähler J, et al. Spt6 regulates intragenic and antisense transcription, nucleosome positioning, and histone modifications genome-wide in fission yeast. Mol Cell Biol. 2013;33:4779-92 pubmed 出版商

Egbert M, Ruetze M, Sattler M, Wenck H, Gallinat S, Lucius R, et al. The matricellular protein periostin contributes to proper collagen function and is downregulated during skin aging. J Dermatol Sci. 2014;73:40-8 pubmed 出版商

Drivas T, Holzbaur E, Bennett J. Disruption of CEP290 microtubule/membrane-binding domains causes retinal degeneration. J Clin Invest. 2013;123:4525-39 pubmed 出版商

Jo S, Kim M, Park J, Kim T, Ahn Y. Txnip contributes to impaired glucose tolerance by upregulating the expression of genes involved in hepatic gluconeogenesis in mice. Diabetologia. 2013;56:2723-32 pubmed 出版商

Barbeau D, La K, Kim D, Kerpedjieva S, Shurin G, Tamama K. Early growth response-2 signaling mediates immunomodulatory effects of human multipotential stromal cells. Stem Cells Dev. 2014;23:155-66 pubmed 出版商

Chen Z, Chen J, Gu Y, Hu C, Li J, Lin S, et al. Aberrantly activated AREG-EGFR signaling is required for the growth and survival of CRTC1-MAML2 fusion-positive mucoepidermoid carcinoma cells. Oncogene. 2014;33:3869-77 pubmed 出版商

Shats I, Gatza M, Liu B, Angus S, You L, Nevins J. FOXO transcription factors control E2F1 transcriptional specificity and apoptotic function. Cancer Res. 2013;73:6056-67 pubmed 出版商

Schreiner A, Durry S, Aida T, Stock M, Ruther U, Tanaka K, et al. Laminar and subcellular heterogeneity of GLAST and GLT-1 immunoreactivity in the developing postnatal mouse hippocampus. J Comp Neurol. 2014;522:204-24 pubmed 出版商

Mach J, Huizer Pajkos A, Cogger V, McKenzie C, Le Couteur D, Jones B, et al. The effect of aging on acetaminophen pharmacokinetics, toxicity and Nrf2 in Fischer 344 rats. J Gerontol A Biol Sci Med Sci. 2014;69:387-97 pubmed 出版商

O Dell L, Natividad L, Pipkin J, Roman F, Torres I, Jurado J, et al. Enhanced nicotine self-administration and suppressed dopaminergic systems in a rat model of diabetes. Addict Biol. 2014;19:1006-19 pubmed 出版商

Ma T, Galimberti F, Erkmen C, Memoli V, Chinyengetere F, SEMPERE L, et al. Comparing histone deacetylase inhibitor responses in genetically engineered mouse lung cancer models and a window of opportunity trial in patients with lung cancer. Mol Cancer Ther. 2013;12:1545-55 pubmed 出版商

Dai C, Sun F, Zhu C, Hu X. Tumor environmental factors glucose deprivation and lactic acidosis induce mitotic chromosomal instability--an implication in aneuploid human tumors. PLoS ONE. 2013;8:e63054 pubmed 出版商

Svensson K, Christianson H, Wittrup A, Bourseau Guilmain E, Lindqvist E, Svensson L, et al. Exosome uptake depends on ERK1/2-heat shock protein 27 signaling and lipid Raft-mediated endocytosis negatively regulated by caveolin-1. J Biol Chem. 2013;288:17713-24 pubmed 出版商

Licandro G, Ling Khor H, Beretta O, Lai J, Derks H, Laudisi F, et al. The NLRP3 inflammasome affects DNA damage responses after oxidative and genotoxic stress in dendritic cells. Eur J Immunol. 2013;43:2126-37 pubmed 出版商

Gal J, Chen J, Barnett K, Yang L, Brumley E, Zhu H. HDAC6 regulates mutant SOD1 aggregation through two SMIR motifs and tubulin acetylation. J Biol Chem. 2013;288:15035-45 pubmed 出版商

Gómez Herreros F, Romero Granados R, Zeng Z, Alvarez Quilón A, Quintero C, Ju L, et al. TDP2-dependent non-homologous end-joining protects against topoisomerase II-induced DNA breaks and genome instability in cells and in vivo. PLoS Genet. 2013;9:e1003226 pubmed 出版商

Pe er T, Lahmi R, Sharaby Y, Chorni E, Noach M, Vecsler M, et al. Gas2l3, a novel constriction site-associated protein whose regulation is mediated by the APC/C Cdh1 complex. PLoS ONE. 2013;8:e57532 pubmed 出版商

Brennan G, Jimenez Mateos E, McKiernan R, Engel T, Tzivion G, Henshall D. Transgenic overexpression of 14-3-3 zeta protects hippocampus against endoplasmic reticulum stress and status epilepticus in vivo. PLoS ONE. 2013;8:e54491 pubmed 出版商

Sirohi K, Chalasani M, Sudhakar C, Kumari A, Radha V, Swarup G. M98K-OPTN induces transferrin receptor degradation and RAB12-mediated autophagic death in retinal ganglion cells. Autophagy. 2013;9:510-27 pubmed 出版商

Lei K, Chen L, Georgiou E, Sooranna S, Khanjani S, Brosens J, et al. Progesterone acts via the nuclear glucocorticoid receptor to suppress IL-1?-induced COX-2 expression in human term myometrial cells. PLoS ONE. 2012;7:e50167 pubmed 出版商

Jarboui M, Bidoia C, Woods E, Roe B, Wynne K, Elia G, et al. Nucleolar protein trafficking in response to HIV-1 Tat: rewiring the nucleolus. PLoS ONE. 2012;7:e48702 pubmed 出版商

Blakemore L, Boes C, Cordell R, Manson M. Curcumin-induced mitotic arrest is characterized by spindle abnormalities, defects in chromosomal congression and DNA damage. Carcinogenesis. 2013;34:351-60 pubmed 出版商

Sasaki M, Miyakoshi M, Sato Y, Nakanuma Y. A possible involvement of p62/sequestosome-1 in the process of biliary epithelial autophagy and senescence in primary biliary cirrhosis. Liver Int. 2012;32:487-99 pubmed 出版商

Ferro M, Giuberti G, Zappavigna S, Perdonà S, Facchini G, Sperlongano P, et al. Chondroitin sulphate enhances the antitumor activity of gemcitabine and mitomycin-C in bladder cancer cells with different mechanisms. Oncol Rep. 2012;27:409-15 pubmed 出版商

An C, Dong Y, Hagiwara N. Genome-wide mapping of Sox6 binding sites in skeletal muscle reveals both direct and indirect regulation of muscle terminal differentiation by Sox6. BMC Dev Biol. 2011;11:59 pubmed 出版商

Hsu F, Yang M, Lin E, Tseng C, Lin H. The significance of Her2 on androgen receptor protein stability in the transition of androgen requirement in prostate cancer cells. Am J Physiol Endocrinol Metab. 2011;300:E902-8 pubmed 出版商

Stoepker C, Hain K, Schuster B, Hilhorst Hofstee Y, Rooimans M, Steltenpool J, et al. SLX4, a coordinator of structure-specific endonucleases, is mutated in a new Fanconi anemia subtype. Nat Genet. 2011;43:138-41 pubmed 出版商

Tong J, Furukawa Y, Sherwin A, Hornykiewicz O, Kish S. Heterogeneous intrastriatal pattern of proteins regulating axon growth in normal adult human brain. Neurobiol Dis. 2011;41:458-68 pubmed 出版商

Tai C, Shen S, Lee W, Liao C, Deng W, Chiou H, et al. Increased cellular apoptosis susceptibility (CSE1L/CAS) protein expression promotes protrusion extension and enhances migration of MCF-7 breast cancer cells. Exp Cell Res. 2010;316:2969-81 pubmed 出版商

Liao C, Luo S, Tsai C, Tsao T, Chen S, Jiang M. CAS Enhances Chemotherapeutic Drug-Induced p53 Accumulation and Apoptosis: Use of CAS for High-Sensitivity Anticancer Drug Screening. Toxicol Mech Methods. 2008;18:771-6 pubmed 出版商

Rossi M, Carbone M, Mostocotto C, Mancone C, Tripodi M, Maione R, et al. Mitochondrial localization of PARP-1 requires interaction with mitofilin and is involved in the maintenance of mitochondrial DNA integrity. J Biol Chem. 2009;284:31616-24 pubmed 出版商

Sasaki M, Yamaguchi J, Ikeda H, Itatsu K, Nakanuma Y. Polycomb group protein Bmi1 is overexpressed and essential in anchorage-independent colony formation, cell proliferation and repression of cellular senescence in cholangiocarcinoma: tissue and culture studies. Hum Pathol. 2009;40:1723-30 pubmed 出版商

Miyajima N, Maruyama S, Nonomura K, Hatakeyama S. TRIM36 interacts with the kinetochore protein CENP-H and delays cell cycle progression. Biochem Biophys Res Commun. 2009;381:383-7 pubmed 出版商

Tsao T, Tsai C, Tung J, Chen S, Yue C, Liao C, et al. Function of CSE1L/CAS in the secretion of HT-29 human colorectal cells and its expression in human colon. Mol Cell Biochem. 2009;327:163-70 pubmed 出版商

Kano S, Miyajima N, Fukuda S, Hatakeyama S. Tripartite motif protein 32 facilitates cell growth and migration via degradation of Abl-interactor 2. Cancer Res. 2008;68:5572-80 pubmed 出版商

Tripathi R, McTigue D. Chronically increased ciliary neurotrophic factor and fibroblast growth factor-2 expression after spinal contusion in rats. J Comp Neurol. 2008;510:129-44 pubmed 出版商

Sasaki M, Ikeda H, Itatsu K, Yamaguchi J, Sawada S, Minato H, et al. The overexpression of polycomb group proteins Bmi1 and EZH2 is associated with the progression and aggressive biological behavior of hepatocellular carcinoma. Lab Invest. 2008;88:873-82 pubmed 出版商

Abdulghani J, Gu L, Dagvadorj A, Lutz J, Leiby B, Bonuccelli G, et al. Stat3 promotes metastatic progression of prostate cancer. Am J Pathol. 2008;172:1717-28 pubmed 出版商

Omura T, Kaneko M, Onoguchi M, Koizumi S, Itami M, Ueyama M, et al. Novel functions of ubiquitin ligase HRD1 with transmembrane and proline-rich domains. J Pharmacol Sci. 2008;106:512-9 pubmed

Sumioka A, Saito Y, Sakuma M, Araki Y, Yamamoto T, Suzuki T. The X11L/X11beta/MINT2 and X11L2/X11gamma/MINT3 scaffold proteins shuttle between the nucleus and cytoplasm. Exp Cell Res. 2008;314:1155-62 pubmed 出版商

Kaneko M, Yasui S, Niinuma Y, Arai K, Omura T, Okuma Y, et al. A different pathway in the endoplasmic reticulum stress-induced expression of human HRD1 and SEL1 genes. FEBS Lett. 2007;581:5355-60 pubmed

Tong J, Hornykiewicz O, Furukawa Y, Kish S. Marked dissociation between high noradrenaline versus low noradrenaline transporter levels in human nucleus accumbens. J Neurochem. 2007;102:1691-1702 pubmed 出版商

Li P, Waters R, Redfern S, Zhang M, Mao L, Annex B, et al. Oxidative phenotype protects myofibers from pathological insults induced by chronic heart failure in mice. Am J Pathol. 2007;170:599-608 pubmed

Nakaya T, Suzuki T. Role of APP phosphorylation in FE65-dependent gene transactivation mediated by AICD. Genes Cells. 2006;11:633-45 pubmed

Bengoechea Alonso M, Punga T, Ericsson J. Hyperphosphorylation regulates the activity of SREBP1 during mitosis. Proc Natl Acad Sci U S A. 2005;102:11681-6 pubmed

Akimoto T, Pohnert S, Li P, Zhang M, Gumbs C, Rosenberg P, et al. Exercise stimulates Pgc-1alpha transcription in skeletal muscle through activation of the p38 MAPK pathway. J Biol Chem. 2005;280:19587-93 pubmed

Trushina E, Dyer R, Badger J, Ure D, Eide L, Tran D, et al. Mutant huntingtin impairs axonal trafficking in mammalian neurons in vivo and in vitro. Mol Cell Biol. 2004;24:8195-209 pubmed

Tsunematsu R, Nakayama K, Oike Y, Nishiyama M, Ishida N, Hatakeyama S, et al. Mouse Fbw7/Sel-10/Cdc4 is required for notch degradation during vascular development. J Biol Chem. 2004;279:9417-23 pubmed

Ruddy M, Wong G, Liu X, Yamamoto H, Kasayama S, Kirkwood K, et al. Functional cooperation between interleukin-17 and tumor necrosis factor-alpha is mediated by CCAAT/enhancer-binding protein family members. J Biol Chem. 2004;279:2559-67 pubmed

Laurent V, Jaubert Miazza L, Desjardins R, Day R, Lindberg I. Biosynthesis of proopiomelanocortin-derived peptides in prohormone convertase 2 and 7B2 null mice. Endocrinology. 2004;145:519-28 pubmed

Cheng S, Shao J, Charlton Kachigian N, Loewy A, Towler D. MSX2 promotes osteogenesis and suppresses adipogenic differentiation of multipotent mesenchymal progenitors. J Biol Chem. 2003;278:45969-77 pubmed

Kudo Y, Kitajjma S, Sato S, Miyauchi M, Ogawa I, Takata T. Establishment of an oral squamous cell carcinoma cell line with high invasive and p27 degradation activities from a lymph node metastasis. Oral Oncol. 2003;39:515-20 pubmed

Lessman C, Kim H. Soluble tubulin complexes in oocytes of the common leopard frog, Rana pipiens, contain gamma-tubulin. Mol Reprod Dev. 2001;60:128-36 pubmed

Iijima K, Ando K, Takeda S, Satoh Y, Seki T, Itohara S, et al. Neuron-specific phosphorylation of Alzheimer's beta-amyloid precursor protein by cyclin-dependent kinase 5. J Neurochem. 2000;75:1085-91 pubmed

Fava F, Raynaud Messina B, Leung Tack J, Mazzolini L, Li M, Guillemot J, et al. Human 76p: A new member of the gamma-tubulin-associated protein family. J Cell Biol. 1999;147:857-68 pubmed

Ando K, Oishi M, Takeda S, Iijima K, Isohara T, Nairn A, et al. Role of phosphorylation of Alzheimer's amyloid precursor protein during neuronal differentiation. J Neurosci. 1999;19:4421-7 pubmed

Roos U, De Brabander M, De Mey J. Indirect immunofluorescence of microtubules in Dictyostelium discoideum. A study with polyclonal and monoclonal antibodies to tubulins. Exp Cell Res. 1984;151:183-93 pubmed