这是一篇来自已证抗体库的有关人类 huntingtin的综述,是根据21篇发表使用所有方法的文章归纳的。这综述旨在帮助来邦网的访客找到最适合huntingtin 抗体。
huntingtin 同义词: HD; IT15; LOMARS

艾博抗(上海)贸易有限公司
domestic rabbit 单克隆(EPR5526)
  • 免疫组化; 人类; 图 1d
  • 免疫印迹; 人类; 1:1000; 图 2a
艾博抗(上海)贸易有限公司 huntingtin抗体(Abcam, ab109115)被用于被用于免疫组化在人类样本上 (图 1d) 和 被用于免疫印迹在人类样本上浓度为1:1000 (图 2a). Front Genet (2021) ncbi
domestic rabbit 单克隆(EPR5526)
  • 免疫印迹; 小鼠; 1:1000; 图 1c
艾博抗(上海)贸易有限公司 huntingtin抗体(Abcam, AB109115)被用于被用于免疫印迹在小鼠样本上浓度为1:1000 (图 1c). Neuropathol Appl Neurobiol (2021) ncbi
domestic rabbit 单克隆(EPR5526)
  • 免疫印迹; 小鼠; 1:5000; 图 5b
艾博抗(上海)贸易有限公司 huntingtin抗体(Abcam, ab109115)被用于被用于免疫印迹在小鼠样本上浓度为1:5000 (图 5b). PLoS Genet (2017) ncbi
domestic rabbit 单克隆(EPR5526)
  • 免疫印迹; 小鼠; 1:3000; 图 3c
艾博抗(上海)贸易有限公司 huntingtin抗体(Abcam, EPR5526)被用于被用于免疫印迹在小鼠样本上浓度为1:3000 (图 3c). J Huntingtons Dis (2016) ncbi
domestic rabbit 单克隆(EPR5526)
  • 免疫印迹; 小鼠; 1:3000; 图 6a
艾博抗(上海)贸易有限公司 huntingtin抗体(Abcam, EPR5526)被用于被用于免疫印迹在小鼠样本上浓度为1:3000 (图 6a). J Huntingtons Dis (2016) ncbi
domestic rabbit 单克隆(EPR5526)
  • 免疫印迹基因敲除验证; 小鼠; 图 3c
艾博抗(上海)贸易有限公司 huntingtin抗体(Abcam, EPR5526)被用于被用于免疫印迹基因敲除验证在小鼠样本上 (图 3c). Proc Natl Acad Sci U S A (2016) ncbi
domestic rabbit 单克隆(EP867Y)
  • 流式细胞仪; 小鼠; 图 s1
艾博抗(上海)贸易有限公司 huntingtin抗体(Abcam, EP867Y)被用于被用于流式细胞仪在小鼠样本上 (图 s1). Sci Rep (2015) ncbi
圣克鲁斯生物技术
小鼠 单克隆(3E10)
  • 免疫组化-自由浮动切片; 小鼠; 1:500; 图 6a
  • 免疫细胞化学; 小鼠; 图 6m
圣克鲁斯生物技术 huntingtin抗体(Santa Cruz, sc-47757)被用于被用于免疫组化-自由浮动切片在小鼠样本上浓度为1:500 (图 6a) 和 被用于免疫细胞化学在小鼠样本上 (图 6m). Nat Neurosci (2019) ncbi
赛信通(上海)生物试剂有限公司
domestic rabbit 单克隆(D7F7)
  • 免疫印迹; 小鼠; 图 4a
赛信通(上海)生物试剂有限公司 huntingtin抗体(Cell Signaling, 5656)被用于被用于免疫印迹在小鼠样本上 (图 4a). elife (2020) ncbi
domestic rabbit 单克隆(D7F7)
  • 免疫印迹; 小鼠; 1:1000; 图 ev1c
赛信通(上海)生物试剂有限公司 huntingtin抗体(Cell signaling, D7F7)被用于被用于免疫印迹在小鼠样本上浓度为1:1000 (图 ev1c). EMBO Mol Med (2020) ncbi
domestic rabbit 单克隆(D7F7)
  • 免疫印迹; 人类; 1:1000; 图 1b
赛信通(上海)生物试剂有限公司 huntingtin抗体(Cell Signaling, D7F7)被用于被用于免疫印迹在人类样本上浓度为1:1000 (图 1b). PLoS ONE (2016) ncbi
Developmental Studies Hybridoma Bank
小鼠 单克隆(MW8)
  • 免疫组化; 小鼠; 1:10; 图 5
Developmental Studies Hybridoma Bank huntingtin抗体(DSHB, MW8)被用于被用于免疫组化在小鼠样本上浓度为1:10 (图 5). Int J Mol Sci (2021) ncbi
小鼠 单克隆(MW7)
  • 免疫组化; 小鼠; 1:1000; 图 7a
Developmental Studies Hybridoma Bank huntingtin抗体(DSHB, MW7)被用于被用于免疫组化在小鼠样本上浓度为1:1000 (图 7a). Nat Commun (2020) ncbi
小鼠 单克隆(MW8)
  • 免疫细胞化学; 人类; 1:100; 图 4i
Developmental Studies Hybridoma Bank huntingtin抗体(DSHB, MW8)被用于被用于免疫细胞化学在人类样本上浓度为1:100 (图 4i). Nat Neurosci (2018) ncbi
小鼠 单克隆(MW8)
  • 免疫组化; 小鼠; 1:750; 图 4a
Developmental Studies Hybridoma Bank huntingtin抗体(DSHB, MW8)被用于被用于免疫组化在小鼠样本上浓度为1:750 (图 4a). Sci Rep (2017) ncbi
小鼠 单克隆(MW1)
  • 免疫印迹; 人类; 1:500
Developmental Studies Hybridoma Bank huntingtin抗体(Developmental Studies Hybridoma Bank, MW1)被用于被用于免疫印迹在人类样本上浓度为1:500. PLoS ONE (2014) ncbi
小鼠 单克隆(MW7)
  • 免疫组化; 人类; 1:100
Developmental Studies Hybridoma Bank huntingtin抗体(Developmental Studies Hybridoma Bank, MW7)被用于被用于免疫组化在人类样本上浓度为1:100. Ann Neurol (2014) ncbi
西格玛奥德里奇
小鼠 单克隆(3B5H10)
  • 免疫印迹; 小鼠; 1:1000; 图 7c
西格玛奥德里奇 huntingtin抗体(Sigma-Aldrich, 3B5H10)被用于被用于免疫印迹在小鼠样本上浓度为1:1000 (图 7c). Sci Rep (2018) ncbi
小鼠 单克隆(3B5H10)
  • 免疫印迹; 小鼠; 图 5c
西格玛奥德里奇 huntingtin抗体(Sigma, P1874)被用于被用于免疫印迹在小鼠样本上 (图 5c). J Huntingtons Dis (2016) ncbi
小鼠 单克隆(3B5H10)
  • 免疫印迹; 小鼠; 1:1000; 图 1
西格玛奥德里奇 huntingtin抗体(Sigma, P1874)被用于被用于免疫印迹在小鼠样本上浓度为1:1000 (图 1). elife (2015) ncbi
小鼠 单克隆(3B5H10)
  • 免疫沉淀; 小鼠
西格玛奥德里奇 huntingtin抗体(Sigma, 3B5H10)被用于被用于免疫沉淀在小鼠样本上. Proc Natl Acad Sci U S A (2013) ncbi
文章列表
  1. Back M, Kurzawa J, Ruggieri S, von Engelhardt J. C57BL/6 Background Attenuates mHTT Toxicity in the Striatum of YAC128 Mice. Int J Mol Sci. 2021;22: pubmed 出版商
  2. Zhang H, Chen N, Deng Z, Mai Y, Deng L, Chen G, et al. Suppression of ANT2 by miR-137 Inhibits Prostate Tumorigenesis. Front Genet. 2021;12:687236 pubmed 出版商
  3. Cheong R, Baldo B, Sajjad M, Kirik D, Peters xe9 n x. Effects of mutant huntingtin inactivation on Huntington disease-related behaviours in the BACHD mouse model. Neuropathol Appl Neurobiol. 2021;47:564-578 pubmed 出版商
  4. Bruyère J, Abada Y, Vitet H, Fontaine G, Deloulme J, Ces A, et al. Presynaptic APP levels and synaptic homeostasis are regulated by Akt phosphorylation of huntingtin. elife. 2020;9: pubmed 出版商
  5. Wu Z, Parry M, Hou X, Liu M, Wang H, Cain R, et al. Gene therapy conversion of striatal astrocytes into GABAergic neurons in mouse models of Huntington's disease. Nat Commun. 2020;11:1105 pubmed 出版商
  6. Ehinger Y, Bruyère J, Panayotis N, Abada Y, Borloz E, Matagne V, et al. Huntingtin phosphorylation governs BDNF homeostasis and improves the phenotype of Mecp2 knockout mice. EMBO Mol Med. 2020;12:e10889 pubmed 出版商
  7. Shen M, Wang F, Li M, Sah N, Stockton M, Tidei J, et al. Reduced mitochondrial fusion and Huntingtin levels contribute to impaired dendritic maturation and behavioral deficits in Fmr1-mutant mice. Nat Neurosci. 2019;22:386-400 pubmed 出版商
  8. Victor M, Richner M, Olsen H, Lee S, Monteys A, Ma C, et al. Striatal neurons directly converted from Huntington's disease patient fibroblasts recapitulate age-associated disease phenotypes. Nat Neurosci. 2018;21:341-352 pubmed 出版商
  9. Juenemann K, Jansen A, van Riel L, Merkx R, Mulder M, An H, et al. Dynamic recruitment of ubiquitin to mutant huntingtin inclusion bodies. Sci Rep. 2018;8:1405 pubmed 出版商
  10. Bragg R, Coffey S, Weston R, Ament S, Cantle J, Minnig S, et al. Motivational, proteostatic and transcriptional deficits precede synapse loss, gliosis and neurodegeneration in the B6.HttQ111/+ model of Huntington's disease. Sci Rep. 2017;7:41570 pubmed 出版商
  11. Nakasuji T, Ogonuki N, Chiba T, Kato T, Shiozawa K, Yamatoya K, et al. Complementary Critical Functions of Zfy1 and Zfy2 in Mouse Spermatogenesis and Reproduction. PLoS Genet. 2017;13:e1006578 pubmed 出版商
  12. Vodicka P, Chase K, Iuliano M, Tousley A, Valentine D, Sapp E, et al. Autophagy Activation by Transcription Factor EB (TFEB) in Striatum of HDQ175/Q7 Mice. J Huntingtons Dis. 2016;5:249-260 pubmed
  13. Vodicka P, Chase K, Iuliano M, Valentine D, Sapp E, Lu B, et al. Effects of Exogenous NUB1 Expression in the Striatum of HDQ175/Q7 Mice. J Huntingtons Dis. 2016;5:163-74 pubmed 出版商
  14. Wang G, Liu X, Gaertig M, Li S, Li X. Ablation of huntingtin in adult neurons is nondeleterious but its depletion in young mice causes acute pancreatitis. Proc Natl Acad Sci U S A. 2016;113:3359-64 pubmed 出版商
  15. Culver B, DeClercq J, Dolgalev I, Yu M, Ma B, Heguy A, et al. Huntington's Disease Protein Huntingtin Associates with its own mRNA. J Huntingtons Dis. 2016;5:39-51 pubmed 出版商
  16. Lopes C, Aubert S, Bourgois Rocha F, Barnat M, Rego A, Déglon N, et al. Dominant-Negative Effects of Adult-Onset Huntingtin Mutations Alter the Division of Human Embryonic Stem Cells-Derived Neural Cells. PLoS ONE. 2016;11:e0148680 pubmed 出版商
  17. Southwell A, Smith S, Davis T, Caron N, Villanueva E, Xie Y, et al. Ultrasensitive measurement of huntingtin protein in cerebrospinal fluid demonstrates increase with Huntington disease stage and decrease following brain huntingtin suppression. Sci Rep. 2015;5:12166 pubmed 出版商
  18. Yao Y, Cui X, Al Ramahi I, Sun X, Li B, Hou J, et al. A striatal-enriched intronic GPCR modulates huntingtin levels and toxicity. elife. 2015;4: pubmed 出版商
  19. Macdonald D, Tessari M, Boogaard I, Smith M, Pulli K, Szynol A, et al. Quantification assays for total and polyglutamine-expanded huntingtin proteins. PLoS ONE. 2014;9:e96854 pubmed 出版商
  20. Cicchetti F, Lacroix S, Cisbani G, Vallières N, Saint Pierre M, St Amour I, et al. Mutant huntingtin is present in neuronal grafts in Huntington disease patients. Ann Neurol. 2014;76:31-42 pubmed 出版商
  21. Sathasivam K, Neueder A, Gipson T, Landles C, Benjamin A, Bondulich M, et al. Aberrant splicing of HTT generates the pathogenic exon 1 protein in Huntington disease. Proc Natl Acad Sci U S A. 2013;110:2366-70 pubmed 出版商