这是一篇有关核纤层蛋白A/C (lamin A/C) 的综述，是根据4篇发表使用实验的文章归纳的。这综述旨在帮助来邦网的访客找到最适合核纤层蛋白A/C siRNA。
核纤层蛋白A/C 同义词: CDCD1; CDDC; CMD1A; CMT2B1; EMD2; FPL; FPLD; FPLD2; HGPS; IDC; LDP1; LFP; LGMD1B; LMN1; LMNC; LMNL1; PRO1; 70 kDa lamin; lamin; lamin A/C-like 1; prelamin-A/C; renal carcinoma antigen NY-REN-32

Thermo Scientific
  • 为了阐明肿瘤细胞需要LPA/S1P受体和三磷酸酶的协同调节来移动，另外在肿瘤前进入侵胶原基质时还需要MT1-MMP蛋白，采用了Dharmacon公司的作用于核纤层蛋白A/C基因的siRNA。ncbi
  • 为了研究β3 integrin介导的vimentin中间纤维细胞表面募集的功能，使用了Dharmacon公司的lamin A/C siRNA作为对照siRNA。ncbi
  • Dharmacon human LMNA (NM_170707) siRNAs 被用于RNA干扰来研究FSHD的分子机理ncbi
  • 为了研究PKCe介导的MARCKS磷酸化在生长锥转向调节中的功能，使用了Dharmacon公司的lamin A/C siRNA作为对照siRNA来抑制DRG神经元中lamin A/C的表达。ncbi
文章列表
  1. Ramona Bhattacharya et al. (2009). "Recruitment of vimentin to the cell surface by beta3 integrin and plectin mediates adhesion strength".PMID 19366731
  2. Alexandre Ottaviani et al. (2009). "The D4Z4 macrosatellite repeat acts as a CTCF and A-type lamins-dependent insulator in facio-scapulo-humeral dystrophy".PMID 19247430
  3. Kevin E Fisher et al. (2006). "Tumor cell invasion of collagen matrices requires coordinate lipid agonist-induced G-protein and membrane-type matrix metalloproteinase-1-dependent signaling".PMID 17156449
  4. Jesse C Gatlin et al. (2006). "Myristoylated, alanine-rich C-kinase substrate phosphorylation regulates growth cone adhesion and pathfinding".PMID 16987960